473 research outputs found

    The functions of examples in the case category description : in the Spanish grammars of the Golden age

    Get PDF
    The article analyzes examples as an integral part of a grammar. The functions of examples in the case category description in the Spanish grammars of the Golden Age are under consideration. It is pointed out that the functions of the examples in the case category description differed greatly from those in the description of other grammatical categoriesyesBelgorod State Universit

    The case category term system in the Spanish grammars of the Golden age

    Get PDF
    The research of linguistic terminology formation peculiarities within the framework of different linguistic traditions gives a rich material for the surveyyesBelgorod State Universit

    Synanthropic flora of Kuzbass

    Get PDF
    The article presents the materials of studies of the adventive flora of the Kemerovo region. For the territory of the Kemerovo region, we identified 244 alien species belonging to 162 genera and 50 families. As a result of the increasing process of invasion of new species into the territory of the region, the need for constant monitoring of alien species for the degree of their naturalization, especially in natural cenoses, is urgent. The problem of synanthropic plant species is becoming increasingly important not only for economically developed territories, but also for the relatively preserved mountain regions of Kuzbass. As a result of the studies, it was found that the synanthropic fraction of the Kuzbass flora, consisting of adventive and apophyte species, accounts for about 18% of the total composition of the flora of vascular plants in the Kemerovo region (60 apophyte species, 244 – advent ones). The revealed heterogeneity in the chorological, ecological and biological terms of the species of the adventive fraction makes it possible to find suitable conditions in various types of ecotopes on the territory of the Kemerovo region. This type of work can serve as a basis for developing a strategy for the preservation of natural phytosystems of Kuzbas

    Effect of triazavirine on the outcome of a lethal influenza infection and secondary bacterial pneumonia following influenza in mice

    Get PDF
    Pneumonia often occurs as secondary infection post influenza disease and accounts for a large proportion of the morbidity and mortality associated with seasonal and pandemic influenza outbreaks. The antiviral drug triazavirine is licensed in Russia for the treatment and prophylaxis of acute respiratory infections, including influenza A and B viruses. In the present study, we investigated the efficacy of triazavirine in a mouse model of secondary Staphylococcus aureus pneumonia following A/California/04/2009 (H1N1)pdm09 influenza virus infection. We also performed a study of the efficacy of triazavirine against the A/California/04/2009 (H1N1)pdm09 lethal influenza infection in mice. In this model, triazavirine at the dose of 25 mg/kg/day significantly enhanced the survival of animals (60% compared to 20%) and the mean survival time to death, prevented weight loss, and reduced viral titer in the lungs of mice infected with influenza virus. At doses of 50 and 100 mg/kg/day, triazavirine was highly effective in the treatment of the secondary bacterial pneumonia following influenza infection in mice. At these doses, triazavirine protected 67-75% of animals against death, increased the mean survival time to death by twofold, and reduced the virus titer by 2.2-3.0 log10TCID50/ml compared to the mice in the control group. These findings suggest the possible benefit of triazavirine treatment in reducing post influenza pneumonia incidence in humans.Pneumonia often occurs as secondary infection post influenza disease and accounts for a large proportion of the morbidity and mortality associated with seasonal and pandemic influenza outbreaks. The antiviral drug triazavirine is licensed in Russia for the treatment and prophylaxis of acute respiratory infections, including influenza A and B viruses. In the present study, we investigated the efficacy of triazavirine in a mouse model of secondary Staphylococcus aureus pneumonia following A/California/04/2009 (H1N1)pdm09 influenza virus infection. We also performed a study of the efficacy of triazavirine against the A/California/04/2009 (H1N1)pdm09 lethal influenza infection in mice. In this model, triazavirine at the dose of 25 mg/kg/day significantly enhanced the survival of animals (60% compared to 20%) and the mean survival time to death, prevented weight loss, and reduced viral titer in the lungs of mice infected with influenza virus. At doses of 50 and 100 mg/kg/day, triazavirine was highly effective in the treatment of the secondary bacterial pneumonia following influenza infection in mice. At these doses, triazavirine protected 67-75% of animals against death, increased the mean survival time to death by twofold, and reduced the virus titer by 2.2-3.0 log10TCID50/ml compared to the mice in the control group. These findings suggest the possible benefit of triazavirine treatment in reducing post influenza pneumonia incidence in humans

    Past distribution of Tilia-feeding Phyllonorycter micromoth (Lepidoptera: Gracillariidae) in the Russian Far East based on survey of historical herbarium

    Get PDF
    Distribution data of Tilia-feeding Phyllonorycter in the Russian Far East have been retrieved from a century-old Tilia herbarium stored in Vladivostok. Overall, 280 typical mines of Phyllonorycter, some with larvae and pupae, were found on 61 out of 799 herbarized specimens of Tilia spp. collected in Khabarovskii krai and Primorskii krai. For the first time, the presence of Tilia-feeding Phyllonorycter has been documented in Amurskaya oblast and Jewish Autonomous oblast. High densities of the leafminer have been recorded on Tilia amurensis sampled in Khabarovskii krai and Primorskii krai between 1937 and 2005 suggesting a population dynamics with recurrent outbreaks. Our results confirm the importance of historical herbarium collections in studying trophic interactions and invasion ecology of folivore organisms

    Variation of the Epiphytic Lichen Diversity in a Gradient of Atmospheric Pollution: Do Taxonomic, Genetic, and Functional Distances between Species Add any Information? GENERAL BIOLOGY

    Get PDF
    22 Studying the influence of reduced biological diver sity on functioning and stability of ecosystems is one of the priorities of modern ecology If the distances between species are important for biodiversity assessment, then strong perturbations that disturb ecosystem equilibrium should lead to signifi cant differences between the indices of diversity and disparity. In this study, we aimed to test this hypothesis using the epiphytic lichen communities, which are extremely sensitive to atmospheric pollution of the biotic component

    Isolation and characterization of a subtilisin-like proteinase of Bacillus intermedius secreted by the Bacillus subtilis recombinant strain AJ73 at different growth stages

    Get PDF
    Two subtilisin-like serine proteinases of Bacillus intermedius secreted by the Bacillus subtilis recombinant strain AJ73 (pCS9) on the 28th and 48th h of culture growth (early and late proteinase, respectively) have been isolated by ion-exchange chromatography on CM-cellulose and by FPLC. Molecular weights of both proteinases were determined. The N-terminal sequences of the recombinant protein and mature proteinases of the original strain were compared. Kinetic parameters and substrate specificities of the early and late proteinase were analyzed. Physicochemical properties of the enzymes were studied. © Nauka/Interperiodica 2007

    Research Culture of Russian University Students

    Get PDF
    The article is devoted to the summarizing results of the sociological study of the re- search culture of students (February-April 2023, n=3,032 people). The aim of the article was to iden- tify its features and contradictions in the conditions of modern Russian universities. The productivity of the theoretical and methodological framework for studying this problem, developed on the basis of L.N. Kogan’s approach, is argued. The article proposes to consider the research culture as a way of developing the essential forces of students and to identify its structural elements such as cognitive, axiological and praxeological. In accordance with the theoretical and methodological approach, the characteristic of the research culture of students is given. The results of the survey allowed us to conclude that the majority of students have an interest in science and scientific knowledge as values, and at the same time – about the formation of a critical assessment of the risks that research produces among students who are active in scientific terms. The problem areas of students’ research competencies that prevent the “seamless” integration of student and “adult” science, including meth- odological and organizational ones, have been identified. Such problematic features of the praxe- ological block of students’ research culture as their low involvement in publication practices and tol- erance to unethical research practices are shown. The significant influence of teachers and scientific mentors performing activating and socializing functions on the formation of the research culture of students is substantiated. The practical significance of the research lies in a comprehensive under- standing of the state of the research culture of students of Russian universities, identifying factors that influence (positively or negatively) its formation and development. On this basis, it is possible to develop scientifically based programs for the academic development of students, especially in terms of its scientific track

    Интегральные соотношения для аналитических решений обобщенного уравнения нестационарной теплопроводности

    Get PDF
    The integral correlations for analytical solutions to the generalized equation of transient heat conduction simultaneously in the Cartesian coordinate grid, cylindrical and spherical coordinate systems for the limited fields of the canonical type were constructed. The theory of integral transformations and the method of Green's functions were developed.Построены интегральные соотношения для аналитических решений обобщенного уравнения нестационарной теплопроводности в декартовой, цилиндрической и сферической системе координат для ограниченных областей канонического типа. Развита теория интегральных преобразований и метод функций Грина
    corecore