2,779 research outputs found

    Warps and correlations with intrinsic parameters of galaxies in the visible and radio

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    From a comparison of the different parameters of warped galaxies in the radio, and especially in the visible, we find that: a) No large galaxy (large mass or radius) has been found to have high amplitude in the warp, and there is no correlation of size/mass with the degree of asymmetry of the warp. b) The disc density and the ratio of dark to luminous mass show an opposing trend: smaller values give more asymmetric warps in the inner radii (optical warps) but show no correlation with the amplitude of the warp; however, in the external radii neither is there any correlation with the asymmetry. c) A third anticorrelation arises from a comparison of the amplitude and degree of asymmetry in the warped galaxies. Hence, it seems that very massive dark matter haloes have nothing to do with the formation of warps but only with the degree of symmetry in the inner radii, and are unrelated to the warp shape for the outermost radii. Denser discs show up the same dependence.Comment: 13 pages, 2 figures, accepted to be published in A&

    Development and Maintenance of the Brain’s Immune Toolkit: Microglia and Non-Parenchymal Brain Macrophages

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    Microglia and non-parenchymal macrophages located in the perivascular space, the meninges and the choroid plexus are independent immune populations that play vital roles in brain development, homeostasis, and tissue healing. Resident macrophages account for a significant proportion of cells in the brain and their density remains stable throughout the lifespan thanks to constant turnover. Microglia develop from yolk sac progenitors, later evolving through intermediate progenitors in a fine-tuned process in which intrinsic factors and external stimuli combine to progressively sculpt their cell type-specific transcriptional profiles. Recent evidence demonstrates that non-parenchymal macrophages are also generated during early embryonic development. In recent years, the development of powerful fate mapping approaches combined with novel genomic and transcriptomic methodologies have greatly expanded our understanding of how brain macrophages develop and acquire specialized functions, and how cell population dynamics are regulated. Here, we review the transcription factors, epigenetic remodeling, and signaling pathways orchestrating the embryonic development of microglia and non-parenchymal macrophages. Next, we describe the dynamics of the macrophage populations of the brain and discuss the role of progenitor cells, to gain a better understanding of their functions in the healthy and diseased brain. (c) 2017 Wiley Periodicals, Inc. Develop Neurobiol 78: 561-579, 2018Spanish Ministry of Economy and Competitiveness (MINECO) with European Regional Development Fund (ERDF) funds; contract grant numbers: BFU201566689, RYC-2013-12817. BBVA Foundation and a Basque Government; contract grant number: PI_2016_1_0011. "Ramon y Cajal" and European Social Fund (ESF) and national resources (MINEICO-AEI); contract grant number: RYC-2015-18056. MINECO co-financed by the European Regional Development Fund (ERDF); contract grant number: SAF2014-60233-JIN. Instituto de Neurociencias is a "Centre of Excellence Severo Ochoa"; contract grant number: SEV-2013-0317. Medical Research Council, Alzheimer's Research UK and The Leverhulme Trust

    Craniometric variation among Brazilian and Scottish populations: a physical anthropology approach

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    The present investigation intended to compare the craniometric variations of two samples of different nationalities (Brazilian and Scottish). Materials and methods: The Brazilian sample consisted of 100 modern complete skulls, including 53 female skulls and 47 male skulls, and the Scottish sample consisted of 100 historical skulls (61 males, 39 females) and 36 mandibles (24 males, 12 females). The cranial measurement protocol was composed of 40 measurements, 11 bilateral and 29 unilateral, and the measurement protocol of the mandible was composed of 15 measurements, with six that were bilateral and nine that were unique. The comparative analysis of the metric variability between the two samples was performed using the means and medians analysis, the t-test, the Wilcoxon test, and the coefficient of variance, with a significance level of 5%. Results: The results showed that, among the 72 analysed variables, 44 measurements (61.11%) presented statistical differences between the samples. The Scottish skull tends to have a cranial length (GOL diff=5.53), breadth (XCB diff=3.78) and height (NPH diff=5.33) greater than the Brazilian skulls, and the Scottish mandibles tend to show a higher mandibular ramus height (MRH diff=9.25), a higher mandibular body height (HMB diff=6.37) and a larger bigonial breadth (BGB diff=5.29) than the Brazilians. The discriminant analysis of the 51 cranial measurements and 21 mandibular measurements showed a variation of the percentage of accuracy between 46.3- 83.8%. Conclusion: The metric analysis demonstrated that there is variability between the two samples studied (61.11%), but a concrete cause cannot be determined considering the multifactorial aspects of the variations of form and size

    Quasinormal modes from potentials surrounding the charged dilaton black hole

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    We clarify the purely imaginary quasinormal frequencies of a massless scalar perturbation on the 3D charged-dilaton black holes. This case is quite interesting because the potential-step appears outside the event horizon similar to the case of the electromagnetic perturbations on the large Schwarzschild-AdS black holes. It turns out that the potential-step type provides the purely imaginary quasinormal frequencies, while the potential-barrier type gives the complex quasinormal modes.Comment: 19 pages, 8 figure

    The Large Aperture GRB Observatory

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    The Large Aperture GRB Observatory (LAGO) is aiming at the detection of the high energy (around 100 GeV) component of Gamma Ray Bursts, using the single particle technique in arrays of Water Cherenkov Detectors (WCD) in high mountain sites (Chacaltaya, Bolivia, 5300 m a.s.l., Pico Espejo, Venezuela, 4750 m a.s.l., Sierra Negra, Mexico, 4650 m a.s.l). WCD at high altitude offer a unique possibility of detecting low gamma fluxes in the 10 GeV - 1 TeV range. The status of the Observatory and data collected from 2007 to date will be presented.Comment: 4 pages, proceeding of 31st ICRC 200

    Water Cherenkov Detectors response to a Gamma Ray Burst in the Large Aperture GRB Observatory

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    In order to characterise the behaviour of Water Cherenkov Detectors (WCD) under a sudden increase of 1 GeV - 1 TeV background photons from a Gamma Ray Burst (GRB), simulations were conducted and compared to data acquired by the WCD of the Large Aperture GRB Observatory (LAGO). The LAGO operates arrays of WCD at high altitude to detect GRBs using the single particle technique. The LAGO sensitivity to GRBs is derived from the reported simulations of the gamma initiated particle showers in the atmosphere and the WCD response to secondaries.Comment: 5 pages, proceeding of the 31st ICRC 200

    Rare t-quark decays tclj+lkt \to c l_j^{+} l_k^{-}, tcνj~νkt \to c \tilde{\nu_j} \nu_k in the minimal four color symmetry model

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    The rare t-quark decays tclj+lkt \to c l_j^{+} l_k^{-}, tcνj~νkt \to c \tilde{\nu_j} \nu_k via the scalar leptoquark doublets are investigated in the minimal four color symmetry model with the Higgs mechanism of the quark-lepton mass splitting. The partial widths of these decays are calculated and the total width of the charged lepton mode Γ(tcl+l)=j,kΓ(tclj+lk) \Gamma(t \to c {l^{+}}' l^{-})= \sum_{j,k} \Gamma(t \to c l_{j}^{+} l_{k}^{-}) and the total width of the neutrino mode Γ(tcν~ν)=j,kΓ(tcνj~νk) \Gamma(t \to c \tilde{\nu}' \nu)= \sum_{j,k} \Gamma(t \to c \tilde{\nu_{j}} \nu_{k}) are found. The corresponding branching ratios are shown to be Br(tcl+l)(3.50.4)105, Br(t \to c {l^{+}}' l^{-}) \approx (3.5 - 0.4) 10^{-5}, Br(tcν~ν)(7.10.8)105 Br(t \to c {\tilde{\nu}}' \nu) \approx (7.1 - 0.8) 10^{-5} for the scalar leptoquark masses mS=180250GeV m_{S}= 180 - 250 GeV and for the appropriate values (sinβ0.2) (\sin{\beta} \approx 0.2) of the mixing angle of the model. The search for such decays at LHC may be of interest.Comment: 18 pages, 2 figures, 1 table, to be published in Modern Physics Letters A; corrected typo

    Probing Topcolor-Assisted Technicolor from Top-Charm Associated Production at LHC

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    We propose to probe the topcolor-assisted technicolor (TC2) model from the top-charm associated productions at the LHC, which are highly suppressed in the Standard Model. Due to the flavor-changing couplings of the top quark with the scalars (top-pions and top-Higgs) in TC2 model, the top-charm associated productions can occur via both the s-channel and t-channel parton processes by exchanging a scalar field at the LHC. We examined these processes through Monte Carlo simulation and found that they can reach the observable level at the LHC in quite a large part of the parameter space of the TC2 model.Comment: Version to appear in PRD (Rapid Communication
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