The behaviour of a single catalyst pellet for the selective hydrogenation of ethyne in ethene

The steady-state and dynamic behaviour of a single Pd---Al2O3 catalyst particle is studied for the selective hydrogenation of ethyne in the presence of ethene, without addition of carbon monoxide. The particle-to-gas heat transfer in the reactor is characterized. During selective hydrogenation, not only the ignition and the extinction phenomena but also oscillatory behaviour is observed. The nature of the single and multipeak oscillations is discussed. With a dynamic model, based on relatively simple kinetic equations and an additional slow mechanism, e.g. the formation of ethylidyne on the catalyst surface, the qualitative features of this system can be described

The Impact of Deuterated CMOS processing on Gate Oxide Reliability

In recent literature, a controversy has arisen over the question whether deuterium improves the stability of the MOS gate dielectric. In particular, the influence of deuterium incorporation on the bulk oxide quality is not clear. In this letter, deuterium or hydrogen is introduced during either the gate oxidation, postoxidation anneal, and/or the postmetal anneal (PMA). The oxide bulk degradation was evaluated using charge-to-breakdown and stress-induced leakage current; and the oxide interface degradation using hot-carrier degradation and low-frequency noise. The obtained results show that the oxide bulk does not benefit from the presence of deuterium, regardless of the stage of deuterium introduction, or the gate oxide thickness. The oxide interface is more stable only when deuterium is introduced in the PMA

Industrial Melanism in the Peppered Moth Is Not Associated with Genetic Variation in Canonical Melanisation Gene Candidates

Industrial melanism in the peppered moth (Biston betularia) is an iconic case study of ecological genetics but the molecular identity of the gene determining the difference between the typical and melanic (carbonaria) morphs is entirely unknown. We applied the candidate gene approach to look for associations between genetic polymorphisms within sixteen a priori melanisation gene candidates and the carbonaria morph. The genes were isolated and sequence characterised in B. betularia using degenerate PCR and from whole-transcriptome sequence. The list of candidates contains all the genes previously implicated in melanisation pattern differences in other insects, including aaNAT, DOPA-decarboxylase, ebony, tan, tyrosine hydroxylase, yellow and yellow2 (yellow-fa). Co-segregation of candidate gene alleles and carbonaria morph was tested in 73 offspring of a carbonaria male-typical female backcross. Surprisingly, none of the sixteen candidate genes was in close linkage with the locus controlling the carbonaria-typical polymorphism. Our study demonstrates that the ‘carbonaria gene’ is not a structural variant of a canonical melanisation pathway gene, neither is it a cis-regulatory element of these enzyme-coding genes. The implication is either that we have failed to characterize an unknown enzyme-coding gene in the melanisation pathway, or more likely, that the ‘carbonaria gene’ is a higher level trans-acting factor which regulates the spatial expression of one or more of the melanisation candidates in this study to alter the pattern of melanin production

Forest Restoration: Do Site Selection and Restoration Practices Follow Ecological Criteria? A Case Study in Sweden

The speed with which restoration will, or can, be accomplished depends on the initial state and location of the sites. However, many factors can undermine the process of choosing sites that are deemed the best ecological choice for restoration. Little attention has been paid to whether site selection follows ecological criteria and how this may affect restoration success. We used habitat inventory data to investigate whether ecological criteria for site selection and restoration have been followed, focusing on restoration for the white-backed woodpecker (Dendrocopos leucotos B.) in Sweden. In our study region, which is situated in an intensively managed forest landscape with dense and young stands dominated by two coniferous species, purely ecological criteria would entail that sites that are targeted for restoration would (1) initially be composed of older and more deciduous trees than the surrounding landscape, and (2) be at a scale relevant for the species. Furthermore, restoration should lead to sites becoming less dense and less dominated by coniferous trees after restoration, which we investigated as an assessment of restoration progress. To contextualize the results, we interviewed people involved in the restoration efforts on site. We show that although the first criterion for ecological site selection was largely met, the second was not. More research is needed to assess the motivations of actors taking part in restoration efforts, as well as how they interlink with public efforts. This would allow us to identify possible synergies that can benefit restoration efforts

Open source software for semi-automated histomorphometry of bone resorption and formation parameters

Micro-CT analysis has become the standard method for assessing bone volume and architecture in small animals. However, micro-CT does not allow the assessment of bone turnover parameters such as bone formation rate and osteoclast (OC) number and surface. For these crucial variables histomorphometric analysis is still an essential technique. Histomorphometry however, is time consuming and, especially in mouse bones, OCs can be difficult to detect. The main purpose of this study was to develop and validate a relatively easy and rapid method to measure static and dynamic bone histomorphometry parameters. Here we present the adaptation of established staining protocols and three novel open source image analysis packages: TrapHisto, OsteoidHisto and CalceinHisto that allow rapid, semi-automated analysis of histomorphometric bone resorption, osteoid, and calcein double labelling parameters respectively. These three programs are based on ImageJ, but use a relatively simple user interface that hides the underlying complexity of the image analysis

Random fields on model sets with localized dependency and their diffraction

For a random field on a general discrete set, we introduce a condition that the range of the correlation from each site is within a predefined compact set D. For such a random field omega defined on the model set Lambda that satisfies a natural geometric condition, we develop a method to calculate the diffraction measure of the random field. The method partitions the random field into a finite number of random fields, each being independent and admitting the law of large numbers. The diffraction measure of omega consists almost surely of a pure-point component and an absolutely continuous component. The former is the diffraction measure of the expectation E[omega], while the inverse Fourier transform of the absolutely continuous component of omega turns out to be a weighted Dirac comb which satisfies a simple formula. Moreover, the pure-point component will be understood quantitatively in a simple exact formula if the weights are continuous over the internal space of Lambda Then we provide a sufficient condition that the diffraction measure of a random field on a model set is still pure-point.Comment: 21 page

The impact of vascular burden on late-life depression.

Small vessel pathology and microvascular lesions are no longer considered as minor players in the fields of cognitive impairment and mood regulation. Although frequently found in cognitively intact elders, both neuroimaging and neuropathological data revealed the negative impact on cognitive performances of their presence within neocortical association areas, thalamus and basal ganglia. Unlike cognition, the relationship between these lesions and mood dysregulation is still a matter of intense debate. Early studies focusing on the role of macroinfarct location in the occurrence of post-stroke depression (PSD) led to conflicting data. Later on, the concept of vascular depression proposed a deleterious effect of subcortical lacunes and deep white matter demyelination on mood regulation in elders who experienced the first depressive episode. More recently, the chronic accumulation of lacunes in thalamus, basal ganglia and deep white matter has been considered as a strong correlate of PSD. We provide here a critical overview of neuroimaging and neuropathological sets of evidence regarding the affective repercussions of vascular burden in the aging brain and discuss their conceptual and methodological limitations. Based on these observations, we propose that the accumulation of small vascular and microvascular lesions constitutes a common neuropathological platform for both cognitive decline and depressive episodes in old age