1,636 research outputs found
Nuclear effects in atomic transitions
Atomic electrons are sensitive to the properties of the nucleus they are
bound to, such as nuclear mass, charge distribution, spin, magnetization
distribution, or even excited level scheme. These nuclear parameters are
reflected in the atomic transition energies. A very precise determination of
atomic spectra may thus reveal information about the nucleus, otherwise hardly
accessible via nuclear physics experiments. This work reviews theoretical and
experimental aspects of the nuclear effects that can be identified in atomic
structure data. An introduction to the theory of isotope shifts and hyperfine
splitting of atomic spectra is given, together with an overview of the typical
experimental techniques used in high-precision atomic spectroscopy. More exotic
effects at the borderline between atomic and nuclear physics, such as parity
violation in atomic transitions due to the weak interaction, or nuclear
polarization and nuclear excitation by electron capture, are also addressed.Comment: review article, 53 pages, 14 figure
Determination of the parameters of a Skyrme type effective interaction using the simulated annealing approach
We implement for the first time the simulated annealing method (SAM) to the
problem of searching for the global minimum in the hyper-surface of the
chi-square function which depends on the values of the parameters of a Skyrme
type effective nucleon-nucleon interaction. We undertake a realistic case of
fitting the values of the Skyrme parameters to an extensive set of experimental
data on the ground state properties of many nuclei ranging from normal to
exotic ones. The set of experimental data used in our fitting procedure
includes the radii for the valence and neutron orbits in
the O and Ca nuclei, respectively, and the breathing mode
energies for several nuclei, in addition to the typically used data on binding
energy, charge radii and spin-orbit splitting. We also include in the fit the
critical density and further constrain the values of the Skyrme
parameters by requiring that (i) the quantity ,
directly related to the slope of the symmetry energy , must be positive for
densities up to (ii) the enhancement factor , associated with
the isovector giant dipole resonance, should lie in the range of
and (iii) the Landau parameter is positive at . We
provide simple but consistent schemes to account for the center of mass
corrections to the binding energy and charge radii.Comment: 33 pages, 4 figures, Phys. Rev. C (in press
Optimization by Quantum Annealing: Lessons from hard 3-SAT cases
The Path Integral Monte Carlo simulated Quantum Annealing algorithm is
applied to the optimization of a large hard instance of the Random 3-SAT
Problem (N=10000). The dynamical behavior of the quantum and the classical
annealing are compared, showing important qualitative differences in the way of
exploring the complex energy landscape of the combinatorial optimization
problem. At variance with the results obtained for the Ising spin glass and for
the Traveling Salesman Problem, in the present case the linear-schedule Quantum
Annealing performance is definitely worse than Classical Annealing.
Nevertheless, a quantum cooling protocol based on field-cycling and able to
outperform standard classical simulated annealing over short time scales is
introduced.Comment: 10 pages, 6 figures, submitted to PR
Uphill and downhill walking in unilateral lower limb amputees
Objective: To study adjustment strategies in unilateral amputees in uphill and downhill walking. Design: observational cohort study. Subjects: Seven transfemoral, 12 transtibial unilateral amputees and 10 able-bodied subjects. Methods: In a motion analysis laboratory the subjects walked over a level surface and an uphill and downhill slope. Gait velocity and lower limb joint angles were measured. Results: In uphill walking hip and knee flexion at initial contact and hip flexion in swing were increased in the prosthetic limb of transtibial amputees. In downhill walking transtibial amputees showed more knee flexion on the prosthetic side in late stance and swing. Transfemoral amputees were not able to increase prosthetic knee flexion in uphill and downhill walking. An important adjustment strategy in both amputee Groups was a smaller hip extension in late stance in uphill and downhill walking, probably related with a shorter step length. In addition, amputees increased knee flexion in early stance in the non-affected limb in uphill walking to compensate for the shorter prosthetic limb length. In downhill walking fewer adjustments were necessary, since the shorter prosthetic limb already resulted in lowering of the body. Conclusion: Uphill and downhill walking can be trained in rehabilitation, which may improve safety and confidence of amputees. Prosthetic design should focus on better control of prosthetic knee flexion abilities without reducing stability. (c) 2007 Elsevier B.V. All fights reserved
The Current Status of Immune Checkpoint Inhibitors in Neuro-Oncology:A Systematic Review
The introduction of immune checkpoint inhibitors (ICI), as a novel treatment modality, has transformed the field of oncology with unprecedented successes. However, the efficacy of ICI for patients with glioblastoma or brain metastases (BMs) from any tumor type is under debate. Therefore, we systematically reviewed current literature on the use of ICI in patients with glioblastoma and BMs. Prospective and retrospective studies evaluating the efficacy and survival outcomes of ICI in patients with glioblastoma or BMs, and published between 2006 and November 2019, were considered. A total of 88 studies were identified (n = 8 in glioblastoma and n = 80 in BMs). In glioblastoma, median progression-free (PFS) and overall survival (OS) of all studies were 2.1 and 7.3 months, respectively. In patients with BMs, intracranial responses have been reported in studies with melanoma and non-small-cell lung cancer (NSCLC). The median intracranial and total PFS in these studies were 2.7 and 3.0 months, respectively. The median OS in all studies for patients with brain BMs was 8.0 months. To date, ICI demonstrate limited efficacy in patients with glioblastoma or BMs. Future research should focus on increasing the local and systemic immunological responses in these patients
Isotope shift in the dielectronic recombination of three-electron ^{A}Nd^{57+}
Isotope shifts in dielectronic recombination spectra were studied for Li-like
^{A}Nd^{57+} ions with A=142 and A=150. From the displacement of resonance
positions energy shifts \delta E^{142,150}(2s-2p_1/2)= 40.2(3)(6) meV
(stat)(sys)) and \delta E^{142,150}(2s-2p_3/2) = 42.3(12)(20) meV of 2s-2p_j
transitions were deduced. An evaluation of these values within a full QED
treatment yields a change in the mean-square charge radius of ^{142,150}\delta
= -1.36(1)(3) fm^2. The approach is conceptually new and combines the
advantage of a simple atomic structure with high sensitivity to nuclear size.Comment: 10 pages, 3 figures, accepted for publication in Physical Review
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Development of a defined compost system for the study of plant-microbe interactions
Plant growth promoting rhizobacteria can improve plant health by providing enhanced nutrition, disease suppression and abiotic stress resistance, and have potential to contribute to sustainable agriculture. We have developed a sphagnum peat-based compost platform for investigating plant-microbe interactions. The chemical, physical and biological status of the system can be manipulated to understand the relative importance of these factors for plant health, demonstrated using three case studies: 1. Nutrient depleted compost retained its structure, but plants grown in this medium were severely stunted in growth due to removal of essential soluble nutrients - particularly, nitrogen, phosphorus and potassium. Compost nutrient status was replenished with the addition of selected soluble nutrients, validated by plant biomass; 2. When comparing milled and unmilled compost, we found nutrient status to be more important than matrix structure for plant growth; 3. In compost deficient in soluble P, supplemented with an insoluble inorganic form of P (Ca3(PO4)2), application of a phosphate solubilising Pseudomonas strain to plant roots provides a significant growth boost when compared with a Pseudomonas strain incapable of solubilising Ca3(PO4)2. Our findings show that the compost system can be manipulated to impose biotic and abiotic stresses for testing how microbial inoculants influence plant growth
Design of a five-axis ultra-precision micro-milling machine—UltraMill. Part 1: Holistic design approach, design considerations and specifications
High-accuracy three-dimensional miniature components and microstructures are increasingly in demand in the sector of electro-optics, automotive, biotechnology, aerospace and information-technology industries. A rational approach to mechanical micro machining is to develop ultra-precision machines with small footprints. In part 1 of this two-part paper, the-state-of-the-art of ultra-precision machines with micro-machining capability is critically reviewed. The design considerations and specifications of a five-axis ultra-precision micro-milling machine—UltraMill—are discussed. Three prioritised design issues: motion accuracy, dynamic stiffness and thermal stability, formulate the holistic design approach for UltraMill. This approach has been applied to the development of key machine components and their integration so as to achieve high accuracy and nanometer surface finish
Improved limits on the weak, neutral, hadronic axial vector coupling constants from quasielastic scattering of polarized electrons.
In scattering polarized electrons (P1 = 44% by 9Be at an energy of 300 MeV at angles 115°⩽ϑ⩽145° a parity violating asymmetry of Acorr = (−3.5 ± 0.7 ± 0.2) × 10−6 was measured. After correction for finite electron polarization and background we deduce an experimental asymmetry of Acx = (−9.4 ± 1.8 ± 0.5) × 10−6. The quoted errors indicate the statistical and the systematic uncertainties, respectively. The asymmetry, which is dominated by the quasielastic cross section, is interpreted in terms of model-independent electron-nucleon coupling constants of the weak neutral current. The error limits in the sector of axial vector coupling constants have been improved by a factor of 3 over previous results. A model-dependent analysis for the Weinberg angle yields the result sin2θw = 0.221 ± 0.014 ± 0.004
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