The Yangian of sl(n|m) and the universal R-matrix

In this paper we study Yangians of sl(n|m) superalgebras. We derive the universal R-matrix and evaluate it on the fundamental representation obtaining the standard Yang R-matrix with unitary dressing factors. For m=0, we directly recover up to a CDD factor the well-known S-matrices for relativistic integrable models with su(N) symmetry. Hence, the universal R-matrix found provides an abstract plug-in formula, which leads to results obeying fundamental physical constraints: crossing symmetry, unitrarity and the Yang-Baxter equation. This implies that the Yangian double unifies all desired symmetries into one algebraic structure. In particular, our analysis is valid in the case of sl(n|n), where one has to extend the algebra by an additional generator leading to the algebra gl(n|n). We find two-parameter families of scalar factors in this case and provide a detailed study for gl(1|1).Comment: 24 pages, 2 figure

Interleukin-18: A Mediator of Inflammation and Angiogenesis in Rheumatoid Arthritis

Interleukin-18 (IL-18) is a highly regulated inflammatory cytokine that is elevated in synovial tissues and synovial fluids of patients with rheumatoid arthritis (RA) compared with patients with osteoarthritis (OA) and patients with other arthropathies. Within the RA joint, IL-18 can contribute to the inflammatory process by inducing leukocyte extravasation through upregulation of endothelial cell adhesion molecules, the release of chemokines from RA synovial fibroblasts, and directly as a monocytes, lymphocyte, and neutrophil chemoattractant. IL-18 can also help maintain and develop the inflammatory pannus by inducing endothelial cell migration and angiogenesis. IL-18 does this directly by binding and activating endothelial cells and indirectly by inducing RA synovial fibroblasts to produce angiogenic chemokines and vascular endothelial growth factor. IL-18 is present in RA synovial fluid in high levels, where it functions as an angiogenic mediator and leukocyte chemoattractant. IL-18 mediates all these inflammatory processes by binding to its receptor, IL-18 receptor, and initiating the activation of different signaling cascades leading to changes in target cells gene expression and behavior. IL-18 has been identified as a potential therapeutic target in the treatment of RA.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90485/1/jir-2E2011-2E0050.pd

Controlling trapping potentials and stray electric fields in a microfabricated ion trap through design and compensation

Recent advances in quantum information processing with trapped ions have demonstrated the need for new ion trap architectures capable of holding and manipulating chains of many (>10) ions. Here we present the design and detailed characterization of a new linear trap, microfabricated with scalable complementary metal-oxide-semiconductor (CMOS) techniques, that is well-suited to this challenge. Forty-four individually controlled DC electrodes provide the many degrees of freedom required to construct anharmonic potential wells, shuttle ions, merge and split ion chains, precisely tune secular mode frequencies, and adjust the orientation of trap axes. Microfabricated capacitors on DC electrodes suppress radio-frequency pickup and excess micromotion, while a top-level ground layer simplifies modeling of electric fields and protects trap structures underneath. A localized aperture in the substrate provides access to the trapping region from an oven below, permitting deterministic loading of particular isotopic/elemental sequences via species-selective photoionization. The shapes of the aperture and radio-frequency electrodes are optimized to minimize perturbation of the trapping pseudopotential. Laboratory experiments verify simulated potentials and characterize trapping lifetimes, stray electric fields, and ion heating rates, while measurement and cancellation of spatially-varying stray electric fields permits the formation of nearly-equally spaced ion chains.Comment: 17 pages (including references), 7 figure

Review of AdS/CFT Integrability: An Overview

This is the introductory chapter of a review collection on integrability in the context of the AdS/CFT correspondence. In the collection we present an overview of the achievements and the status of this subject as of the year 2010.Comment: 31 pages, v2: reference added, references to other chapters updated, v3: footnote 1 on location of references added, v4: minor changes, references added, accepted for publication in Lett. Math. Phys, v5: minor corrections, links to chapters updated, attached IntAdS.pdf with all chapters in one file, see http://arxiv.org/src/1012.3982/anc/IntAdS.pdf or http://www.phys.ethz.ch/~nbeisert/IntAdS.pd

Demonstration of integrated microscale optics in surface-electrode ion traps

In ion trap quantum information processing, efficient fluorescence collection is critical for fast, high-fidelity qubit detection and ion-photon entanglement. The expected size of future many-ion processors require scalable light collection systems. We report on the development and testing of a microfabricated surface-electrode ion trap with an integrated high numerical aperture (NA) micromirror for fluorescence collection. When coupled to a low NA lens, the optical system is inherently scalable to large arrays of mirrors in a single device. We demonstrate stable trapping and transport of 40Ca+ ions over a 0.63 NA micromirror and observe a factor of 1.9 enhancement in photon collection compared to the planar region of the trap.Comment: 15 pages, 8 figure