Visualization of dynamics using local dynamic modelling with self organizing maps

In this work, we describe a procedure to visualize nonlinear process dynamics using a self-organizing map based local model dynamical estimator. The proposed method exploits the topology preserving nature of the resulting estimator to extract visualizations (planes) of insightful dynamical features, that allow to explore nonlinear systems whose behavior changes with the operating point. Since the visualizations are obtained from a dynamical model of the process, measures on the goodness of this estimator (such as RMSE or AIC) are also applicable as a measure of the trustfulness of the visualizations. To illustrate the application of the proposed method, an experiment to analyze the dynamics of a nonlinear system on different operating points is include

Assessing the conservation value of waterbodies: the example of the Loire floodplain (France)

In recent decades, two of the main management tools used to stem biodiversity erosion have been biodiversity monitoring and the conservation of natural areas. However, socio-economic pressure means that it is not usually possible to preserve the entire landscape, and so the rational prioritisation of sites has become a crucial issue. In this context, and because floodplains are one of the most threatened ecosystems, we propose a statistical strategy for evaluating conservation value, and used it to prioritise 46 waterbodies in the Loire floodplain (France). We began by determining a synthetic conservation index of fish communities (Q) for each waterbody. This synthetic index includes a conservation status index, an origin index, a rarity index and a richness index. We divided the waterbodies into 6 clusters with distinct structures of the basic indices. One of these clusters, with high Q median value, indicated that 4 waterbodies are important for fish biodiversity conservation. Conversely, two clusters with low Q median values included 11 waterbodies where restoration is called for. The results picked out high connectivity levels and low abundance of aquatic vegetation as the two main environmental characteristics of waterbodies with high conservation value. In addition, assessing the biodiversity and conservation value of territories using our multi-index approach plus an a posteriori hierarchical classification methodology reveals two major interests: (i) a possible geographical extension and (ii) a multi-taxa adaptation

New single-ended objective measure for non-intrusive speech quality evaluation

peer-reviewedThis article proposes a new output-based method for non-intrusive assessment of speech quality of voice communication systems and evaluates its performance. The method requires access to the processed (degraded) speech only, and is based on measuring perception-motivated objective auditory distances between the voiced parts of the output speech to appropriately matching references extracted from a pre-formulated codebook. The codebook is formed by optimally clustering a large number of parametric speech vectors extracted from a database of clean speech records. The auditory distances are then mapped into objective Mean Opinion listening quality scores. An efficient data-mining tool known as the self-organizing map (SOM) achieves the required clustering and mapping/reference matching processes. In order to obtain a perception-based, speaker-independent parametric representation of the speech, three domain transformation techniques have been investigated. The first technique is based on a perceptual linear prediction (PLP) model, the second utilises a bark spectrum (BS) analysis and the third utilises mel-frequency cepstrum coefficients (MFCC). Reported evaluation results show that the proposed method provides high correlation with subjective listening quality scores, yielding accuracy similar to that of the ITU-T P.563 while maintaining a relatively low computational complexity. Results also demonstrate that the method outperforms the PESQ in a number of distortion conditions, such as those of speech degraded by channel impairments.acceptedpeer-reviewe

Comparative Coastal Risk Index (CCRI): A multidisciplinary risk index for Latin America and the Caribbean

As the world's population grows to a projected 11.2 billion by 2100, the number of people living in low-lying areas exposed to coastal hazards is projected to increase. Critical infrastructure and valuable assets continue to be placed in vulnerable areas, and in recent years, millions of people have been displaced by natural hazards. Impacts from coastal hazards depend on the number of people, value of assets, and presence of critical resources in harm's way. Risks related to natural hazards are determined by a complex interaction between physical hazards, the vulnerability of a society or social-ecological system and its exposure to such hazards. Moreover, these risks are amplified by challenging socioeconomic dynamics, including poorly planned urban development, income inequality, and poverty. This study employs a combination of machine learning clustering techniques (Self Organizing Maps and K-Means) and a spatial index, to assess coastal risks in Latin America and the Caribbean (LAC) on a comparative scale. The proposed method meets multiple objectives, including the identification of hotspots and key drivers of coastal risk, and the ability to process large-volume multidimensional and multivariate datasets, effectively reducing sixteen variables related to coastal hazards, geographic exposure, and socioeconomic vulnerability, into a single index. Our results demonstrate that in LAC, more than 500,000 people live in areas where coastal hazards, exposure (of people, assets and ecosystems) and poverty converge, creating the ideal conditions for a perfect storm. Hotspot locations of coastal risk, identified by the proposed Comparative Coastal Risk Index (CCRI), contain more than 300,00 people and include: El Oro, Ecuador; Sinaloa, Mexico; Usulutan, El Salvador; and Chiapas, Mexico. Our results provide important insights into potential adaptation alternatives that could reduce the impacts of future hazards. Effective adaptation options must not only focus on developing coastal defenses, but also on improving practices and policies related to urban development, agricultural land use, and conservation, as well as ameliorating socioeconomic conditions

Synthetic Mimic of Antimicrobial Peptide with Nonmembrane-Disrupting Antibacterial Properties

Proteolysis in dairy lactic acid bacteria has been studied in great detail by genetic, biochemical and ultrastructural methods. From these studies the picture emerges that the proteolytic systems of lactococci and lactobacilli are remarkably similar in their components and mode of action. The proteolytic system consists of an extracellularly located serine-proteinase, transport systems specific for di-tripeptides and oligopeptides (> 3 residues), and a multitude of intracellular peptidases. This review describes the properties and regulation of individual components as well as studies that have led to identification of their cellular localization. Targeted mutational techniques developed in recent years have made it possible to investigate the role of individual and combinations of enzymes in vivo. Based on these results as well as in vitro studies of the enzymes and transporters, a model for the proteolytic pathway is proposed. The main features are: (i) proteinases have a broad specificity and are capable of releasing a large number of different oligopeptides, of which a large fraction falls in the range of 4 to 8 amino acid residues; (ii) oligopeptide transport is the main route for nitrogen entry into the cell; (iii) all peptidases are located intracellularly and concerted action of peptidases is required for complete degradation of accumulated peptides.