Nyvltova et al. ICP-MS Data

ICP-MS analysis of proteins immunoprecipitated with beads conjugated with FLAG antibody (anti-DYDDDDDK beads, Sigma), from mitochondrial extracts of wild-type HEK293T (negative control) and COX11-KO+COX11-FLAG, COX11-KO+COX11C219D-FLAG, COX11-KO+PET91-FLAG, COX11-KO+PET91C30+41D-FLAG, PET191-KO+PET191-FLAG and PET191-KO+PET191C30+41D-FLAG. 16mg of isolated mitochondria was used for each sample, for each analysis. Three independent repetitions were performed.THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV

Entamoeba Encystation: New Targets to Prevent the Transmission of Amebiasis

mebiasis is caused by Entamoeba histolytica infection and can produce a broad range of clinical signs, from asymptomatic cases to patients with obvious symptoms. The current epidemiological and clinical statuses of amebiasis make it a serious public health problem worldwide. The Entamoeba life cycle consists of the trophozoite, the causative agent for amebiasis, and the cyst, the form responsible for transmission. These two stages are connected by “encystation” and “excystation.” Hence, developing novel strategies to control encystation and excystation will potentially lead to new measures to block the transmission of amebiasis by interrupting the life cycle of the causative agent. Here, we highlight studies investigating encystation using inhibitory chemicals and categorize them based on the molecules inhibited. We also present a perspective on new strategies to prevent the transmission of amebiasis