70 research outputs found
Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase
The influence of the Hall force on the vortex dynamics in type II superconductors
The effect of the Hall force on the pinning of vortices in type II
superconductors is considered. A field theoretic formulation of the pinning
problem allows a non-perturbative treatment of the influence of quenched
disorder. A self-consistent theory is constructed using the diagrammatic
functional method for the effective action, and an expression for the pinning
force for independent vortices as well as vortex lattices is obtained. We find
that the pinning force for a single vortex is suppressed by the Hall force at
low temperatures while it is increased at high temperatures. The effect of the
Hall force is more pronounced on a single vortex than on a vortex lattice. The
results of the self-consistent theory are shown to be in good agreement with
numerical simulations.Comment: 9 pages, 4 figures, published in Physical Review
Correction: Interactions of prototype foamy virus capsids with host cell polo-like kinases are important for efficient viral DNA integration.
[This corrects the article DOI: 10.1371/journal.ppat.1005860.]
Trapped Antihydrogen in Its Ground State
Antihydrogen atoms are confined in an Ioffe trap for 15 to 1000 seconds --
long enough to ensure that they reach their ground state. Though
reproducibility challenges remain in making large numbers of cold antiprotons
and positrons interact, 5 +/- 1 simultaneously-confined ground state atoms are
produced and observed on average, substantially more than previously reported.
Increases in the number of simultaneously trapped antithydrogen atoms are
critical if laser-cooling of trapped antihydrogen is to be demonstrated, and
spectroscopic studies at interesting levels of precision are to be carried out
The {\eta}'-carbon potential at low meson momenta
The production of mesons in coincidence with forward-going
protons has been studied in photon-induced reactions on C and on a
liquid hydrogen (LH) target for incoming photon energies of 1.3-2.6 GeV at
the electron accelerator ELSA. The mesons have been identified
via the decay
registered with the CBELSA/TAPS detector system. Coincident protons have been
identified in the MiniTAPS BaF array at polar angles of . Under these kinematic constraints the
mesons are produced with relatively low kinetic energy (
150 MeV) since the coincident protons take over most of the momentum of the
incident-photon beam. For the C-target this allows the determination of the
real part of the -carbon potential at low meson momenta by
comparing with collision model calculations of the kinetic energy
distribution and excitation function. Fitting the latter data for
mesons going backwards in the center-of-mass system yields a potential depth of
V = (44 16(stat)15(syst)) MeV, consistent with earlier
determinations of the potential depth in inclusive measurements for average
momenta of 1.1 GeV/. Within the experimental
uncertainties, there is no indication of a momentum dependence of the
-carbon potential. The LH data, taken as a reference to check
the data analysis and the model calculations, provide differential and integral
cross sections in good agreement with previous results for
photoproduction off the free proton.Comment: 9 pages, 13 figures. arXiv admin note: text overlap with
arXiv:1608.0607
Mode-locking in driven vortex lattices with transverse ac-drive and random pinning
We find mode-locking steps in simulated current-voltage characteristics of
driven vortex lattices with {\it random} pinning when an applied ac-current is
{\it perpendicular} to the dc-current. For low frequencies there is
mode-locking only above a non-zero threshold ac force amplitude, while for
large frequencies there is mode-locking for any small ac force. This is
consistent with the nature of {\it transverse} temporal order in the different
regimes in the absence of an applied ac-drive. For large frequencies the
magnitude of the fundamental mode-locked step depends linearly with the ac
force amplitude.Comment: 4 pages, 4 figures, .tar.gz fil
A semiconductor laser system for the production of antihydrogen
Laser-controlled charge exchange is a promising method for producing cold antihydrogen. Caesium atoms in Rydberg states collide with positrons and create positronium. These positronium atoms then interact with antiprotons, forming antihydrogen. Las er excitation of the caesium atoms is essential to increase the cross section of the charge-exchange collisions. This method was demonstrated in 2004 by the ATRAP collaboration by using an available copper vapour laser. For a second generation of charge-e xchange experiments we have designed a new semiconductor laser system that features several improvements compared to the copper vapour laser. We describe this new laser system and show the results from the excitation of caesium atoms to Rydberg states wit hin the strong magnetic fields in the ATRAP apparatus
Photoproduction of eta mesons from the neutron: cross sections and double polarization observable E
Photoproduction of mesons from neutrons} \abstract{Results from
measurements of the photoproduction of mesons from quasifree protons and
neutrons are summarized. The experiments were performed with the CBELSA/TAPS
detector at the electron accelerator ELSA in Bonn using the
decay. A liquid deuterium target was used for the
measurement of total cross sections and angular distributions. The results
confirm earlier measurements from Bonn and the MAMI facility in Mainz about the
existence of a narrow structure in the excitation function of . The current angular distributions show a forward-backward
asymmetry, which was previously not seen, but was predicted by model
calculations including an additional narrow state. Furthermore, data
obtained with a longitudinally polarized, deuterated butanol target and a
circularly polarized photon beam were analyzed to determine the double
polarization observable . Both data sets together were also used to extract
the helicity dependent cross sections and . The
narrow structure in the excitation function of
appears associated with the helicity-1/2 component of the reaction
Формирование имиджа компании как работодателя: аннотация к дипломной работе / Баглай Ольга Мирославовна; Факультет философии и социальных наук; Кафедра социальной коммуникации; научный руководитель: Купчинова Татьяна Владимировна
Unlike for other retroviruses, only a few host cell factors that aid the replication of foamy viruses (FVs) via interaction with viral structural components are known. Using a yeast-two-hybrid (Y2H) screen with prototype FV (PFV) Gag protein as bait we identified human polo-like kinase 2 (hPLK2), a member of cell cycle regulatory kinases, as a new interactor of PFV capsids. Further Y2H studies confirmed interaction of PFV Gag with several PLKs of both human and rat origin. A consensus Ser-Thr/Ser-Pro (S-T/S-P) motif in Gag, which is conserved among primate FVs and phosphorylated in PFV virions, was essential for recognition by PLKs. In the case of rat PLK2, functional kinase and polo-box domains were required for interaction with PFV Gag. Fluorescently-tagged PFV Gag, through its chromatin tethering function, selectively relocalized ectopically expressed eGFP-tagged PLK proteins to mitotic chromosomes in a Gag STP motif-dependent manner, confirming a specific and dominant nature of the Gag-PLK interaction in mammalian cells. The functional relevance of the Gag-PLK interaction was examined in the context of replication-competent FVs and single-round PFV vectors. Although STP motif mutated viruses displayed wild type (wt) particle release, RNA packaging and intra-particle reverse transcription, their replication capacity was decreased 3-fold in single-cycle infections, and up to 20-fold in spreading infections over an extended time period. Strikingly similar defects were observed when cells infected with single-round wt Gag PFV vectors were treated with a pan PLK inhibitor. Analysis of entry kinetics of the mutant viruses indicated a post-fusion defect resulting in delayed and reduced integration, which was accompanied with an enhanced preference to integrate into heterochromatin. We conclude that interaction between PFV Gag and cellular PLK proteins is important for early replication steps of PFV within host cells
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