Statements with Meaning of Conditionality as Means of Creating WAR Concept in K. Simonov’s Idiostyle

The article is devoted to the role of statements with the meaning of conditionality in the creation of the conceptual sphere of a literary work. The relevance of the study is determined by the attention of modern philological science to the essence of the individual author’s concept, as well as the growing interest of linguists in the text functions of language units. The material of the study was K. Simonov’s trilogy “The Living and the Dead,” in which syntactic constructions with conjunctions of conditionality group are the dominant linguistic means. It is hypothesized that conjunctions that provide links meaningful for the overall content of the text are actively involved in the construction of key artistic meanings. The components of the artistic concept of WAR, modeled on the basis of statements with conjunctions if and though , are presented. It is shown that constructions with relations of conditionality participate in the formation of conceptual and emotional components of the artistic concept of WAR. The study contributes to the expansion of ideas about the functions of functional parts of speech and helps to present the prospect of their further study in the textual aspect

On Actual Direction of Linguopoetics: Russian Conjunctions in Text Service (History of Issue)

The article is a review of scientific data on the study of text functions of Russian unions. The main stages of the linguists’ interest in the artistic potentials of Russian language coordinating and subordinating conjunctions as part of the syntactic constructions of literary works are described. The article emphasizes that the combined results of the research indicate the effectiveness of syndesis as one of the means of creating a functional, communicative and pragmatic essence of a literary text. It is stated that the study of conjunctive sentences in the text perspective is an actual and developing direction, but the general theory of text functions of Russian conjunctions has not yet fully developed. The author considers that it is expedient to reveal the methodological mechanism of interaction of deep private meanings of conjunctive utterances in the process of their participation in creation of the conceptual meaning of a literary work equal to the author’s intention. The present study promotes the expansion of ideas about the functions of functional parts of speech in the artistic narrative, and also outlines the prospects for the study of other Russian conjunctions in the textual aspect

Reforming the Russian police in the light of public opinion

The article is devoted to the analysis of police reform in the light of public opinion. The questions of optimization of police activity are considered. Статья посвящена анализу реформы полиции в свете общественного мнения. Рассмотрены вопросы оптимизации деятельности полиции

Specifics of geological composition, geochemistry and geochronology of rocks from the Kresty alkaline-ultrabasic massif (Maimecha-Kotui province, Polar Siberia)

In this work, we demonstrate new data that allows us to accurate geochronological ranges of formation of the Kresty alkaline-ultrabasic massif, which is considered to be a satellite of the Gulinian giant pluton. We also interpreted geological, geochemical and isotope-geochemical data obtained earlier for major varieties of this volcanic-plutonic association taking into account new geochronological results, as well as considered new aspects/information on matter source of alkaline-ultrabasic massifs from this province. One of the main aspects is interaction of Siberian super plume matter with hosting substrate of Siberian craton continental crust

Chronic Methamphetamine Administration Causes Differential Regulation of Transcription Factors in the Rat Midbrain

Methamphetamine (METH) is an addictive and neurotoxic psychostimulant widely abused in the USA and throughout the world. When administered in large doses, METH can cause depletion of striatal dopamine terminals, with preservation of midbrain dopaminergic neurons. Because alterations in the expression of transcription factors that regulate the development of dopaminergic neurons might be involved in protecting these neurons after toxic insults, we tested the possibility that their expression might be affected by toxic doses of METH in the adult brain. Male Sprague-Dawley rats pretreated with saline or increasing doses of METH were challenged with toxic doses of the drug and euthanized two weeks later. Animals that received toxic METH challenges showed decreases in dopamine levels and reductions in tyrosine hydroxylase protein concentration in the striatum. METH pretreatment protected against loss of striatal dopamine and tyrosine hydroxylase. In contrast, METH challenges caused decreases in dopamine transporters in both saline- and METH-pretreated animals. Interestingly, METH challenges elicited increases in dopamine transporter mRNA levels in the midbrain in the presence but not in the absence of METH pretreatment. Moreover, toxic METH doses caused decreases in the expression of the dopamine developmental factors, Shh, Lmx1b, and Nurr1, but not in the levels of Otx2 and Pitx3, in saline-pretreated rats. METH pretreatment followed by METH challenges also decreased Nurr1 but increased Otx2 and Pitx3 expression in the midbrain. These findings suggest that, in adult animals, toxic doses of METH can differentially influence the expression of transcription factors involved in the developmental regulation of dopamine neurons. The combined increases in Otx2 and Pitx3 expression after METH preconditioning might represent, in part, some of the mechanisms that served to protect against METH-induced striatal dopamine depletion observed after METH preconditioning

Clinical researches of a specialized sports nutrition product “Hemosport” for the regulation of hemoglobin levels in adolescent girls who are professionally involved in sports

The aim of the research was a clinical assessment of the effectiveness of the developed specialized sports nutrition product for regulating the level of hemoglobin in adolescent girls professionally involved in sports.Materials and methods: 23 girls — athletes of various sports specialization were researched during a training camp. The athletes were determined by the clinical parameters of blood, its general analysis and biochemical parameters, then the physical endurance and performance were assessed.Results: the developed product “Hemosport” demonstrated efficiency in most of the researched parameters in the main group compared with the control. The positive dynamics of most of the researched indicators revealed a general tendency to improve the state of vital organs and systems of the body of athletes of the main group, to increase their adaptive capabilities and vegetative balance.Conclusions: clinical studies of the specialized product “Hemosport” allow it to be recommended in the practice of sports nutrition for adolescent girls of 12–17 years old who are professionally involved in sports to compensate for iron deficiency nutritional deficiencies specific for this group of athletes, as well as to increase the efficiency and effectiveness of their training