Performance of imaging studies in patients with suspected appendicitis after stratification with adult appendicitis score

Background: Diagnostic scoring is used to stratify patients with suspected appendicitis into three groups: high, intermediate, and low probability of appendicitis. The stratification can be used for selective imaging to avoid the harms of radiation without compromising diagnostic accuracy. The aim was to study how stratification by Adult Appendicitis Score affects diagnostic performance of imaging studies. Methods: Analysis of 822 patients who underwent diagnostic imaging for suspected appendicitis was made. Adult Appendicitis Score was used to stratify patients into groups of high, intermediate, and low probability of appendicitis. Diagnostic performance of computed tomography (CT) and ultrasound (US) was compared between these patient groups. Results: After scoring, pre-test probability of appendicitis ranged from 9-16% in low probability group to 75-79% in high probability group in patients who underwent US or CT. Post-test probability of appendicitis after positive CT was 99, 91, and 75% in high probability, intermediate probability and low probability groups, respectively, p <0.001. After positive US the respective probabilities were 95, 91 and 42%, p <0.001. Conclusion: Diagnostic imaging has limited value in patients with low probability of appendicitis according to Adult Appendicitis Score.Peer reviewe

Advancing environmental sustainability through nature-based science tourism: The potential of universities

This review examines the potential of universities to advance environmental sustainability through nature-based science tourism, in which scientists are actively involved in co-creating nature-based tourism experiences. We first justify the review by presenting the current changes facing academia, namely the pressure to increase societal effectiveness, science democratization, and environmental sustainability. Then, we define science tourism and address the role of science and scientists in nature-based tourism. Finally, we evaluate the potential of nature-based science tourism to affect tourists’ environmental knowledge, attitudes and behavior. Based on previous literature, we suggest that universities and scientists, who have the knowledge about environmental sustainability, biodiversity crisis, and climate change, could have a more significant role in providing nature-based tourism experiences and shaping tourists’ attitudes and behavior regarding environmental sustainability. In line with recent discussions on science dissemination, this requires not only providing scientific knowledge to large audiences but also active scientific engagement and interaction with tourists

A new adult appendicitis score improves diagnostic accuracy of acute appendicitis - a prospective study

Peer reviewe

Quantitative proteomic analysis of bronchoalveolar lavage fluid in West Highland white terriers with canine idiopathic pulmonary fibrosis

Background Canine idiopathic pulmonary fibrosis (CIPF) is a chronic, progressive, interstitial fibrosing lung disease, manifesting as cough, exercise intolerance and ultimately, dyspnea and respiratory failure. It mainly affects West Highland white terriers (WHWTs), lacks curable treatment and has a poor prognosis. Aspiration of gastroesophageal refluxate may play a role in the development of CIPF. In the first part of this study, we completed label-free quantitative proteomic analysis of bronchoalveolar lavage fluid (BALF) from CIPF and healthy WHWTs. In the second part, we evaluated potential protein markers of reflux aspiration from canine gastric juice and vomitus and whether these were present in BALF from the two groups. Results Across all BALF samples, 417 proteins were identified, and of these, 265 proteins were identified by two or more unique tryptic peptides. Using the 265 high confidence assignments, the quantitative proteome profiles were very similar in the two cohorts, but they could be readily resolved by principal component analysis on the basis of differential protein expression. Of the proteins that were differentially abundant in the two groups, several (including inflammatory and fibrotic markers) were elevated in CIPF, and a smaller, more diverse group of proteins were diminished in CIPF. No protein markers indicative of reflux aspiration were identified. Conclusions Label-free proteomics allowed discrimination between CIPF and healthy WHWTs, consistent with fibrotic process but did not provide clear evidence for gastrointestinal aspiration. The measurement of proteins may provide a proteomics signature of CIPF that could be used to evaluate treatment options.Peer reviewe

Healthy and Unhealthy Food Consumption in Relation to Quality of Life among Finnish Female Municipal Employees: A Cross-Sectional Study

Aspects of good quality of life (QoL) have been found to motivate people to make lifestyle changes. There is also evidence that certain dietary patterns are associated with QoL. The aim of this work was to examine whether consumption frequencies of healthy and unhealthy food items are associated with QoL in female employees. A cross-sectional study was conducted among 631 Finnish female employees (mean age 49 years, SD = 10) from 10 municipal work units in 2015. Information about the participants was collected by physical examination, laboratory tests, self-administered questionnaires, including the Food Frequency Questionnaire (FFQ), and from medical history. QoL was assessed with the EUROHIS-Quality of Life 8-item index. A significant positive association was seen between consumption frequency of healthy foods and the EUROHIS-QOL mean score (p = 0.002). The association was small but comprehensive, also involving most dimensions of QoL. The consumption frequency of unhealthy foods was not associated with QoL. These findings are relevant when designing diet counselling, since QoL is an outcome that has been found to motivate people to change their health habits. Recommending abundant use of healthy foods could be a simple and convenient way of diet counselling at many health care appointments, where time consuming approaches are difficult to conduct

Advancing environmental sustainability through nature-based science tourism: The potential of universities

This review examines the potential of universities to advance environmental sustainability through nature-based science tourism, in which scientists are actively involved in co-creating nature-based tourism experiences. We first justify the review by presenting the current changes facing academia, namely the pressure to increase societal effectiveness, science democratization, and environmental sustainability. Then, we define science tourism and address the role of science and scientists in nature-based tourism. Finally, we evaluate the potential of nature-based science tourism to affect tourists’ environmental knowledge, atitudes and behavior. Based on previous literature, we suggest that universities and scientists, who have the knowledge about environmental sustainability, biodiversity crisis, and climate change, could have a more significant role in providing nature-based tourism experiences and shaping tourists’ attitudes and behavior regarding environmental sustainability. In line with recent discussions on science dissemination, this requires not only providing scientific knowledge to large audiences but also active scientific engagement and interaction with tourists.</div

More Active Mobility in Everyday Life: Finland Benefits from Reducing Car Use

The Ministry of Transport and Communications’ National Programme for the Promotion of Walking and Cycling aims to increase the combined modal share of walking and cycling from the current 30% to 35–38% by 2030. In order to achieve the target, the current measures are not enough. Without more decisive action, the health, economic, and environmental benefits of increasing walking and cycling will remain a dream. Cities have a long tradition of car-based transport and urban planning. This is reflected in the reduced physical activity and, consequently, the decline in public health and increasing health care costs. While the car-centric lifestyle still prevails, there are weak signals of a shift towards more active, healthy, and sustainable mobility patterns: carlessness is becoming more common in dense and large cities. In the Oulu region, the popularity of cycling is significant compared to other urban areas in Finland. In Helsinki, the conditions for reducing car use have increased. According to the recent national studies measuring school children’s physical activity, children in urban areas are more active than those in rural areas. Behaviour change takes time. To bring about and consolidate change, we need to better understand people’s daily lives as well as create long-term plans across different sectors and levels of government to support active travel. This policy brief is the first in its series from the Healthy Lifestyles to Boost Sustainable Growth (STYLE) project, combining interdisciplinary knowledge on trends in transport and physical activity. Interpreting them through infrastructure and service designs and changing lifestyles, we generate insight on novel business opportunities and intervention models that induce physical activity. This provides innovative pathways towards current national policy targets and promotion of the societal vision. The project is funded by the Strategic Research Council at the Academy of Finland. Read more: www.styletutkimus.fi/e

Conceptualizing nature-based science tourism: a case study of Seili Island, Finland

Nature-based tourism has been widely addressed, yet research on nature-based science tourism, founded on science, scientific knowledge, and/or engagement in scientific research, is still scarce. Drawing on tourist motivation, nature-based tourism, special interest tourism, and science tourism, a novel theoretical conceptualization of nature-based science tourism was developed. The framework identified three categories of science tourism with intensifying levels of tourists' interest in scientific knowledge and tourist engagement: tourism based on scientific knowledge, tourism with scientific adventure or volunteering, and scientific research tourism. In the empirical part, the framework was applied to Seili Island, Finland, and tourist motivation to nature-based science tourism was examined through a survey (n = 518). According to the results, tourists were interested in science and nature-based science tourism products, especially guided tours involving scientific interpretation, but also in intensive scientific excursions. Learning was a dominant motivation, but enjoying nature and escape and relaxation were also significant. When moving from guided tours to more intensive scientific excursions, motivations diversified; besides learning, other tourist motivations also need to be addressed in developing nature-based science tourism experiences. The study contributes to nature-based tourism and underresearched science tourism literature and provides practical implications for developing nature-based tourism