Chemical Association via Exact Thermodynamic Formulations

It can be fruitful to view two-component physical systems of attractive monomers, A and B, ``chemically'' in terms of a reaction A + B C, where C = AB is an associated pair or complex. We show how to construct free energies in the three-component or chemical picture which, under mass-action equilibration, exactly reproduce any given two-component or ``physical'' thermodynamics. Order-by-order matching conditions and closed-form chemical representations reveal the freedom available to modify the A-C, B-C, and C-C interactions and to adjust the association constant. The theory (in the simpler one-component, i.e., A = B, case) is illustrated by treating a van der Waals fluid.Comment: 15 double-spaced pages (RevTeX), including 1 eps figur

'O lugar escuro': o mal de alzheimer sob as óticas literária e jurídica

O I Encontro Internacional do MALOCA Grupo de Estudos Multidisciplinares em Urbanismos e Arquiteturas do Sul teve por objetivo apresentar os resultados do seu primeiro triênio (2014-2016) e debater os rumos das pesquisas do grupo para o triênio 2017-2019. Divulgamos agora os Anais Eletrônicos do I Encontro, que aconteceu em outubro de 2017 na Universidade Federal da Integração Latino-Americana (UNILA). Confiram no link: https://revistas.unila.edu.br/anaismaloca/index :)O artigo objetiva um exercício de reflexão sobre o processo de interdição de pessoas com o mal de Alzheimer propiciado por aproximações de duas perspectivas diferentes: a narrativa literária e o discurso jurídico. Para a primeira perspectiva utilizaremos a obra ―O Lugar Escuro‖, da escritora Heloisa Seixas, centrada no tema da doença de Alzheimer. O processo senil narrado é evidenciado em sua faceta dolorosa que aflige tanto o personagem - pela degradante perda da autonomia – quanto os familiares. O romance é caracterizado como autobiográfico, mantendo seu apelo ficcional. Para a segunda, analisaremos a jurisprudência para detalhar o processo de interdição de pessoas com o mal de Alzheimer e exploraremos os recursos do Judiciário que se utiliza de documentos extrajurídicos para fundamentar-se. Um exemplo é a emissão de laudos médicos como condição a ensejar a interdição das pessoas portadoras da doença, atestando-as incapazes pela perda da capacidade civil. A aproximação permitirá ver como a construção dessa doença nas duas perspectivas tem como eixo o significado da senilidade como ausência de autonomia e de capacidade no contexto brasileiro recente.The article aims at an exercise of reflection on the process of banning people with Alzheimer 's disease brought about by approaches from two different perspectives: literary narrative and legal discourse. For the first perspective we will use the work "The Dark Place", by the writer Heloisa Seixas, focused on the theme of Alzheimer's disease. The senile process narrated is evidenced in its painful facet that afflicts both the character - by the degrading loss of autonomy - and the relatives. The novel is characterized as autobiographical, retaining its fictional appeal. For the second, we will look at case law to detail the process of banning people with Alzheimer's disease, and we will explore the resources of the Judiciary that uses extrajudicial documents to substantiate. An example is the issuance of medical reports as a condition to induce the interdiction of people carrying the disease, attesting them incapable of loss of civilian capacity. The approach will allow us to see how the construction of this disease in both perspectives has as its axis the meaning of senility as absence of autonomy and capacity in the recent Brazilian contextGrupo de Estudos Multidisciplinar em Urbanismo e Arquitetura do Sul - MALOC

Slowing of axonal regeneration is correlated with increased axonal viscosity during aging

<p>Abstract</p> <p>Background</p> <p>As we age, the speed of axonal regeneration declines. At the biophysical level, why this occurs is not well understood.</p> <p>Results</p> <p>To investigate we first measured the rate of axonal elongation of sensory neurons cultured from neonatal and adult rats. We found that neonatal axons grew 40% faster than adult axons (11.5 µm/hour vs. 8.2 µm/hour). To determine how the mechanical properties of axons change during maturation, we used force calibrated towing needles to measure the viscosity (stiffness) and strength of substrate adhesion of neonatal and adult sensory axons. We found no significant difference in the strength of adhesions, but did find that adult axons were 3 times intrinsically stiffer than neonatal axons.</p> <p>Conclusions</p> <p>Taken together, our results suggest decreasing axonal stiffness may be part of an effective strategy to accelerate the regeneration of axons in the adult peripheral nervous system.</p

Ion detection in the photoionization of a Rb Bose-Einstein condensate

Two-photon ionization of Rubidium atoms in a magneto-optical trap and a Bose-Einstein condensate (BEC) is experimentally investigated. Using 100 ns laser pulses, we detect single ions photoionized from the condenstate with a 35(10)% efficiency. The measurements are performed using a quartz cell with external electrodes, allowing large optical access for BECs and optical lattices.Comment: 14 pages, 7 figure

Severe Acute Hepatocellular Injury Attributed to OxyELITE Pro: A Case Series

Herbal and dietary supplement (HDS) hepatotoxicity is increasingly being reported in the United States. This case series describes the presenting clinical features and outcomes of 7 patients with liver injury attributed to OxyELITE Pro enrolled in the Drug Induced Liver Injury Network (DILIN) study

Using a Frontline Staff Intervention to Improve Cervical Cancer Screening in a Large Academic Internal Medicine Clinic

BACKGROUND: Cervical cancer is the third most common malignancy affecting women. Screening with Papanicolaou (Pap) tests effectively identifies precancerous lesions and early-stage cervical cancer. While the nationwide rate of cervical cancer screening (CCS) is 84%, our urban general internal medicine (GIM) clinic population had a CCS rate of 70% in 2016. OBJECTIVE: To improve our clinic\u27s CCS rate to match or exceed the national average within 18 months by identifying barriers and testing solutions. DESIGN: A quality improvement project led by a multidisciplinary group of healthcare providers. PARTICIPANTS: Our GIM clinic includes 16 attending physicians, 116 resident physicians, and 20 medical assistants (MAs) with an insured and underserved patient population. INTERVENTION: Phase 1 lasted 9 months and implemented CCS patient outreach, patient financial incentives, and clinic staff education. Phase 2 lasted 9 months and involved a workflow change in which MAs identified candidates for CCS during patient check-in. Feedback spanned the entire study period. MAIN MEASURES: Our primary outcome was the number of Pap tests completed per month during the 2 study phases. Our secondary outcome was the clinic population\u27s CCS rate for all eligible clinic patients. KEY RESULTS: After interventions, the average number of monthly Pap tests increased from 35 to 56 in phase 1 and to 75 in phase 2. Of 385 patients contacted in phase 1, 283 scheduled a Pap test and 115 (41%) completed it. Compared to baseline, both interventions improved cervical cancer screening (phase 1 relative risk, 1.86; 95% CI, 1.64-2.10; P \u3c 0.001; phase 2 relative risk, 2.70; 95% CI, 2.40-3.02; P \u3c 0.001). Our clinic\u27s CCS rate improved from 70% to 75% after the 18-month intervention. CONCLUSIONS: The rate of CCS increased by 5% after a systematic 2-phase organizational intervention that empowered MAs to remind, identify, and prepare candidates during check-in for CCS