Cryopyrin-associated periodic fever syndrome manifesting as Tolosa-Hunt syndrome

Background Tolosa-Hunt syndrome (THS) is characterized by unilateral orbital pain, ipsilateral oculomotor paresis and a prompt response to treatment with corticosteroids. Several reports have demonstrated that the clinical features of THS are not specific to one causal aetiology and can lead to misdiagnosis. Case report We report the case of a patient diagnosed with THS after an episode of unilateral orbital pain and diplopia with demonstration of granulomatous inflammation of both cavernous sinus on cerebral magnetic resonance imaging and an immediate response to treatment with corticosteroids. Progression of the disease over the following years, accompanied by increasing signs of inflammation on cerebral magnetic resonance imaging and cerebrospinal fluid pleocytosis, led to further diagnostic tests. Genetic analyses revealed a heterozygote low-penetrance mutation (Q703K) of the cryopyrin/NLRP3 gene compatible with a cryopyrin-associated periodic fever syndrome. Discussion This case report demonstrates that THS can be a central nervous system manifestation of cryopyrin-associated periodic fever syndrome, which therefore represents a differential diagnosis of THS, even in elderly patients

Medium effects on phi decays to dilepton and kaon-antikaon pairs in relativistic heavy ion reactions

We consider the role of rescattering of secondary kaons on the dilepton branching ratio of the phi meson. In-medium mass modifications and broadening of kaons and phi mesons are taken into account. We find in the framework of a Bjorken scenario for the time evolution of the expanding fireball that the phi yield from dimuons is moderately or at least only slightly enhanced compared to that from kaon-antikaon pairs. The relation to experimental yields measured by the NA49, NA50 and CERES Collaborations at CERN SPS and the PHENIX Collaboration at RHIC is discussed.Comment: 6 pages with 2 figures, accepted for publication in Eur. Phys. J.

Isobaric and Isochoric Heat Capacities of Imidazolium-Based and Pyrrolidinium-Based Ionic Liquids as Function of Temperature: Modeling of Isobaric Heat Capacity

International audienceThe isobaric and isochoric heat capacities of seven 1-alkyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imides, two 1-alkyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imides, and two bis(1-alkyl-3-methylimidazolium) tetrathiocyanatocobaltates were determined at atmospheric pressure in the temperature range from 293.15 to 323.15 K. The isobaric heat capacities were determined by means of differential scanning calorimetry, whereas isochoric heat capacities were determined along with isothermal compressibilities indirectly by means of the acoustic method from the speed of sound and density measurements. Based on the experimental data, as expected, the isobaric heat capacity increases linearly with increasing alkyl chain length in the cation of 1-alkyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imides and no odd and even carbon number effect is observed. After critical comparison of the obtained data with the available literature data, the most reliable values are recommended. It has been also shown that, although the COSMOthermX calculations underestimated the isobaric heat capacity values whatever the temperature and the ionic liquid structure, the approach used during this work may be applied to estimate physical properties of non-single-charged ions as well. Additionally, based on the speeds of sound the thermal conductivities were calculated using a modified Bridgman relation

Analisis Integrasi Padi Ikan Dalam Perspektif Agro Ekonomi

This study aimed to obtain information integration rice fish viewed from the perspective of agroeconomics. This study is motivated by the growth rate of rice production which likely to decline, decline in soil fertility due to continuous intensification. The method used was a survey method by taking the case of rice - fish farming in Solokan Jeruk District Bandung Regency West Java Province. Purposive sampling is used in this research. The expected benefit is to increase rice production, fish seed supply, income and welfare of farmers and the development of efficient utilization of paddy fields. The results showed the integration of fish rice as seen as agro-economic was positively gave the benefit for both farmers and for agricultural land itself. Keywords: rice, agro-econom

Effects of training and motivation on auditory P300 brain–computer interface performance

Objectives Brain–computer interface (BCI) technology aims at helping end-users with severe motor paralysis to communicate with their environment without using the natural output pathways of the brain. For end-users in complete paralysis, loss of gaze control may necessitate non-visual BCI systems. The present study investigated the effect of training on performance with an auditory P300 multi-class speller paradigm. For half of the participants, spatial cues were added to the auditory stimuli to see whether performance can be further optimized. The influence of motivation, mood and workload on performance and P300 component was also examined. Methods In five sessions, 16 healthy participants were instructed to spell several words by attending to animal sounds representing the rows and columns of a 5 × 5 letter matrix. Results 81% of the participants achieved an average online accuracy of ≥70%. From the first to the fifth session information transfer rates increased from 3.72 bits/min to 5.63 bits/min. Motivation significantly influenced P300 amplitude and online ITR. No significant facilitative effect of spatial cues on performance was observed. Conclusions Training improves performance in an auditory BCI paradigm. Motivation influences performance and P300 amplitude. Significance The described auditory BCI system may help end-users to communicate independently of gaze control with their environment

Investigation of Coolant Mixing in Reactor VVER-1000

We present an experimental investigation of coolant mixing in downcomer and lower plenum of VVER-1000 here. The arrangement of the problem, the methodology and results are discussed. Three groups of experiments simulating coolant mixing were executed: in conditions of RCP start-up, during natural circulation recovery in the course of SB LOCA and in conditions of stable operation of different amount of RCPs. Results of experiments are used for validation of numerical codes