5,318 research outputs found
The origin of stereotypes about Russia in France
Image of Russia that exists in France is studied on the basis of classical literature. Severe climate (cold winter) is regarded as a constant.Рассматривается аннотация представлений о России во Франции, преимущественно на материале классической литературы. В качестве константы указываются суровые климатические условия (холодная зима)
Harmonic maps and twistorial structures
We introduce the notion of Riemannian twistorial structure and we show that
it provides new natural constructions of harmonic maps.Comment: 15 page
Reef response to sea-level and environmental changes during the last deglaciation: Integrated Ocean Drilling Program Expedition 310, Tahiti Sea Level
The last deglaciation is characterized by a rapid sea-level rise and coeval abrupt environmental changes. The Barbados coral reef record suggests that this period has been punctuated by two brief intervals of accelerated melting (meltwater pulses, MWP), occurring at 14.08-13.61 ka and 11.4-11.1 ka (calendar years before present), that are superimposed on a smooth and continuous rise of sea level. Although their timing, magnitude, and even existence have been debated, those catastrophic sea-level rises are thought to have induced distinct reef drowning events. The reef response to sea-level and environmental changes during the last deglacial sea-level rise at Tahiti is reconstructed based on a chronological, sedimentological, and paleobiological study of cores drilled through the relict reef features on the modern forereef slopes during the Integrated Ocean Drilling Program Expedition 310, complemented by results on previous cores drilled through the Papeete reef. Reefs accreted continuously between 16 and 10 ka, mostly through aggradational processes, at growth rates averaging 10 mm yr-1. No cessation of reef growth, even temporary, has been evidenced during this period at Tahiti. Changes in the composition of coralgal assemblages coincide with abrupt variations in reef growth rates and characterize the response of the upward-growing reef pile to nonmonotonous sea-level rise and coeval environmental changes. The sea-level jump during MWP 1A, 16 ± 2 m of magnitude in ~350 yr, induced the retrogradation of shallow-water coral assemblages, gradual deepening, and incipient reef drowning. The Tahiti reef record does not support the occurrence of an abrupt reef drowning event coinciding with a sea-level pulse of ~15 m, and implies an apparent rise of 40 mm yr-1 during the time interval corresponding to MWP 1B at Barbados. © 2012 Geological Society of America
Implications of CP violating 2HDM in B physics
The charged fermion mass matrices are invariant under symmetry
linked to the fermion number transformation. Under the condition that the
definition of this symmetry in arbitrary weak basis does not depend upon Higgs
parameters such as ratio of vacuum expectation values, a class of two Higgs
doublet models (2HDM) can be identified in which tree level flavor changing
neutral currents normally present in 2HDM are absent. However unlike the type I
or type II Higgs doublet models, the charged Higgs couplings in these models
contain additional flavor dependent CP violating phases. These phases can
account for the recent hints of the beyond standard model CP violation in the
and mixing. In particular, there is a range of parameters in which
new phases do not contribute to the meson CP violation but give identical
new physics phases in the and meson mixing.Comment: 7 pages, 1 figure, Talk given by Bhavik P. Kodrani at 16th
International Symposium on Particles, Strings and Cosmology, July 19th -
23rd, 2010, Valencia, Spai
Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1
The Epstein-Barr virus (EBV) nuclear antigen 3 family of protein is critical for the EBV-induced primary B-cell growth transformation process. Using a yeast two-hybrid screen we identified 22 novel cellular partners of the EBNA3s. Most importantly, among the newly identified partners, five are known to play direct and important roles in transcriptional regulation. Of these, the Myc-interacting zinc finger protein-1 (MIZ-1) is a transcription factor initially characterized as a binding partner of MYC. MIZ-1 activates the transcription of a number of target genes including the cell cycle inhibitor CDKN2B. Focusing on the EBNA3A/MIZ-1 interaction we demonstrate that binding occurs in EBV-infected cells expressing both proteins at endogenous physiological levels and that in the presence of EBNA3A, a significant fraction of MIZ-1 translocates from the cytoplasm to the nucleus. Moreover, we show that a trimeric complex composed of a MIZ-1 recognition DNA element, MIZ-1 and EBNA3A can be formed, and that interaction of MIZ-1 with nucleophosmin (NPM), one of its coactivator, is prevented by EBNA3A. Finally, we show that, in the presence of EBNA3A, expression of the MIZ-1 target gene, CDKN2B, is downregulated and repressive H3K27 marks are established on its promoter region suggesting that EBNA3A directly counteracts the growth inhibitory action of MIZ-1
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