6,114 research outputs found
Impaired Oxidative Status Is Strongly Associated with Cardiovascular Risk Factors
The main target of primary prevention is the identification of cardiovascular risk factors aimed at reducing of the adverse impact of modifiable factors, such as lifestyle and pharmacological treatments. In humans, an alteration of the oxidative status has been associated with several pathologies, including diabetes and cardiovascular diseases. However, the prognostic relevance of circulating oxidative stress biomarkers remains poorly understood. Our study explored, in a healthy population (n=322), the relationship between oxidative status and cardiovascular risk factors. Here, we were successful in demonstrating that plasmatic oxidative status is significantly associated with traditional cardiovascular risk factors. We revealed a significant depletion in the efficacy of total plasma antioxidant barrier in high cardiovascular risk categories, and we confirmed an age-related alteration of oxidative status. The efficacy of total plasma antioxidant barrier is significantly depleted in relation to metabolic disorders. Interestingly, the cholesterol imbalance is the main factor in depleting the efficacy of total plasma antioxidant barrier. The oxidative status is also influenced by hypertension, and a slight increase in systolic blood pressure determines a highly significant effect. We showed that the first detectable event of a redox disturbance is the repairing intervention of the antioxidant barrier that is thus decreased as overutilized
1,3 dipolar cycloadditions of azides on enamines: more than 50 years in a “Click”
Experimental and numerical investigations on slender panels with holes under symmetrical localised loads
Perforated steel girders under a single or combined in plane loading have been largely studied in the literature. However, such investigations were trusted on the numerical modelling and FEM analysis and due to the lack of experimental results in most cases, the accuracy of the numerical model and the consideration of imperfections in the FEM analyses are open to reflexion. In this paper, a series of experimental tests are performed to study the post-critical behaviour of perforated steel girders. Ten full scales steel girders were tested under uniaxial compressive force. Amongst them, four were used as control specimens whereas a circular hole was located in the center of the other six. The parameters such as the geometry of the web plate, the position of the hole and the plate slenderness are found as those most influencing the post-critical behaviour. Finally, the experimental results were used to validate the intensive numerical analyses. The results obtained showed the strong influence of combined geometrical imperfections and residual stresses on the mid-plane Von Mises stresses
Three years field trials to assess the effect of kaolin made particles and copper on olive-fruit fly (B.oleae Gmelin) infestations in Sicily
In most countries of Mediterranean Basin, Bactrocera oleae (Gmel), the olive fruit fly, is the key pest insect on olives. In Sicily this pest causes losses of fruits and a poor quality olive oil. Many researchers have recently carried out some field studies which were based on the use of kaolin and copper against the olive-fruit fly. In the last years these products have been effective several times in reducing olive fly infestation. Kaolin had, also, some important effect in reducing heat-stress in fruit crops and olive-trees.
The aim of the present study was to assess the effect of kaolin and copper treatment on olive infestations in Sicily and to evaluate chemical and sensory parameters of oils extracted. For this reason, within 2003-2005, the IX Servizio of Assessorato Regionale Agricoltura e Foreste, selected some olive groves where to carry out trials with kaolin and copper and to realize information and divulgation activities
Diagnosis by Documentary: Professional Responsibilities in Informal Encounters
Most work addressing clinical workers' professional responsibilities concerns the norms of conduct within established professional-patient relationships, but such responsibilities may extend beyond the clinical context. We explore health workers' professional responsibilities in such "informal" encounters through the example of a doctor witnessing the misdiagnosis and mistreatment of a serious long-term condition in a television documentary, arguing that neither internalist approaches to professional responsibility (such as virtue ethics or care ethics) nor externalist ones (such as the "social contract" model) provide sufficiently clear guidance in such situations. We propose that a mix of both approaches, emphasizing the noncomplacency and practical wisdom of virtue ethics, but grounding the normative authority of virtue in an external source, is able to engage with the health worker's responsibilities in such situations to the individual, the health care system, and the population at large
Surveying the spirit of absolute summability on multilinear operators and homogeneous polynomials
[EN] We draw a fundamental compendium of the most valuable results of the theory
of summing linear operators and detail those that are not shared by known multilinear and
polynomial extensions of absolutely summing linear operators. The lack of such results in the
theory of non-linear summing operators justifies the introduction of a class of polynomials
and multilinear operators that satisfies at once all related non-linear results. Surprisingly
enough, this class, defined by means of a summing inequality, happens to be the well known
ideal of composition with a summing operator.D. Pellegrino acknowledges with thanks the support of CNPq Grant 401735/2013-3-PVE (Linha 2)-Brazil. P. Rueda acknowledges with thanks the support of the Ministerio de Economia y Competitividad (Spain) MTM2011-22417. E. A. Sanchez Perez acknowledges with thanks the support of the Ministerio de Economia y Competitividad (Spain) MTM2012-36740-C02-02.Pellegrino, D.; Rueda, P.; Sánchez PĂ©rez, EA. (2016). Surveying the spirit of absolute summability on multilinear operators and homogeneous polynomials. Revista de la Real Academia de Ciencias Exactas FĂsicas y Naturales Serie A Matemáticas. 110(1):285-302. https://doi.org/10.1007/s13398-015-0224-8S2853021101Achour, D., Dahia, E., Rueda, P., Sánchez-PĂ©rez, E.A.: Factorization of absolutely continuous polynomials. J. Math. Anal. Appl. 405(1), 259–270 (2013)Albiac, F., Kalton, N.: Topics in Banac Space Theory. 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A 99, 195–212 (1999)Montanaro, A.: Some applications of hypercontractive inequalities in quantum information theory. J. Math. Phys. 53(12), 122–206 (2012)Mujica, J.: Complex analysis in Banach spaces. Dover Publications, Mineola (2010)Pellegrino, D.: Cotype and absolutely summing homogeneous polynomials in L p spaces. Studia Math. 157, 121–131 (2003)Pellegrino, D., Ribeiro, J.: On multi-ideals and polynomial ideals of Banach spaces: a new approach to coherence and compatibility. Monatsh. Math. 173(3), 379–415 (2014)Pellegrino, D., Santos, J.: A general Pietsch domination theorem. J. Math. Anal. Appl. 375, 371–374 (2011)Pellegrino, D., Santos, J.: Absolutely summing multilinear operators: a panorama. Quaest. Math. 34(4), 447–478 (2011)Pellegrino, D., Santos, J.: On summability of nonlinear mappings: a new approach. Math. Z. 270(1–2), 189–196 (2012)Pellegrino, D., Santos, J., Seoane-SepĂşlveda, J.B.: Some techniques on nonlinear analysis and applications. Adv. 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