194 research outputs found

    Perspectivas en epistemología de la psicología

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    Investigar es teorizar. Los científicos intentan construir explicaciones capaces de trascender los límites de lo particular y concreto que caracterizan a la experiencia. El propósito de este trabajo es revisar los aportes epistemológicos en lo referente a la evolución de la ciencia, en general, y de la psicología, en particular. Con Thomas Kuhn e Imre Lakatos la epistemología se desplazó desde un énfasis popperiano en la lógica de la ciencia hacia la historia y la sociología de la ciencia. Con tal movimiento se reconfiguraron las nociones fundamentales de la epistemología general y de las epistemologías regionales tal como ocurre, por ejemplo, con la epistemología de la psicología. Si bien resulta deseable la superación de la fragmentación en psicología, su constatación no es de ninguna manera indicativa de minoría epistemológica. La investigación psicológica actual posee una identidad claramente científica. Sus estudios emplean, básicamente, métodos hipotético-deductivos que generan teorías falsables. Sus aportes presentan todas las características que usualmente se emplean en epistemología para categorizar a una disciplina como científica. En este contexto, la psicología futura presentará un énfasis aún mayor en la ciencia y una búsqueda de integración en torno a un paradigma unificador, como características epistemológicas preponderantes para las próximas décadas

    Programa de prevenção e controle da anemia infecciosa eqüina no Pantanal Sul-Mato-Grossense.

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    A Anemia Infecciosa Eqüina (AIE), conhecida mundialmente como febre-do-pântano, é causada por um retrovírus pertencente à subfamília dos lentivírus, que infecta membros da família Equidae. Os estudos iniciais dessa doença foram realizados na França, no século XIX, e, atualmente, apresenta distribuição mundial. A AIE é uma infecção persistente, resultando em episódios periódicos de febre, anemia, hemorragias, redução no número de glóbulos brancos e plaquetas com supressão transitória da resposta imunológica. Sinais clínicos como perda de peso, depressão , desorientação, andar em círculos e febre tem sido observados. Muitos animais não apresentam qualquer sinal clínico (portadores assintomáticos) associado à AIE. O aproveitamento de potros negativos, oriundos de éguas positivas para AIE, é possível, visto que os potros raramente apresentam-se infectados ao nascimento. O desmame dos potros deve ser realizado aos seis meses de idade. Antes dessa idade, a maioria dos potros apresenta resultados positivos ao exame de AIE (IDGA), provavelmente por causa dos anticorpos presentes no colostro, os quais permanecem circulantes no sangue. O desmame não deve ser realizado mais tarde, uma vez qua a atratividade dos potros com relação aos vetores tende a aumentar com a idade, juntamente com o risco de transmissão (Silva et al., 2001).bitstream/item/81125/1/DOC68.pd

    Reviewing, indicating, and counting books for modern research evaluation systems

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    In this chapter, we focus on the specialists who have helped to improve the conditions for book assessments in research evaluation exercises, with empirically based data and insights supporting their greater integration. Our review highlights the research carried out by four types of expert communities, referred to as the monitors, the subject classifiers, the indexers and the indicator constructionists. Many challenges lie ahead for scholars affiliated with these communities, particularly the latter three. By acknowledging their unique, yet interrelated roles, we show where the greatest potential is for both quantitative and qualitative indicator advancements in book-inclusive evaluation systems.Comment: Forthcoming in Glanzel, W., Moed, H.F., Schmoch U., Thelwall, M. (2018). Springer Handbook of Science and Technology Indicators. Springer Some corrections made in subsection 'Publisher prestige or quality

    Understanding Business Travel Time and Its Place in the Working Day

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    This article argues that there is a need to understand business travel time in the context of the wider organization of work time. It considers why travel time use is potentially changing with the use of mobile technologies by the increasing number of individuals engaged in ‘knowledge work’, and examines existing evidence that indicates that travel time use is part of a wider work-related ‘taskscape’. However, it not only considers material productive output, but suggests that travel time as ‘time out’ from work-related activities also plays a vital role for employees. It also suggests that business travel time use that is not of benefit to the employer may not be at the employer's expense. This is contrasted with the assumptions used in UK transport appraisal. Data gathered from the autumn 2004 wave of the National Rail Passenger Survey (GB) is used to illustrate some key issues concerning productivity and ‘anti-activity’. A case study of an individual business traveller then points towards the need for a new approach to exploring the role played by travel time in the organization of work practices to be considered. © 2008, Sage Publications. All rights reserved

    In Digital We Trust: The Computerisation of Retail Finance in Western Europe and North America

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    This paper tells of the contents of a forthcoming volume, which offers a new and original approach to the study of technological change in retail finance. Most business history studies of businesses for the last 50 years note the emergence of computers and computer applications, but they do not analyze their role in shaping business practices and organizations. In this book we look directly at the processes of mechanisation and computerisation of retail financial services, throughout the 20th Century while articulating an international comparison. We bring together young, well established and independent historians, who come from different traditions (that is, economic, business, accounting, geography and political histories as well as historians of technology). Contributors look at stand alone and comparative case studies from different parts of the world (namely Britain, Denmark, France, Germany, Netherlands, Spain, Sweden, Mexico and the USA). The outcome is a rich survey of the broad literature examining different aspects of the technological and business histories of retail financial markets from a variety of perspectives

    Influence of Shear-Thinning Rheology on the Mixing Dynamics in Taylor-Couette Flow

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    Non‐Newtonian rheology can have a significant effect on mixing efficiency, which remains poorly understood. The effect of shear‐thinning rheology in a Taylor‐Couette reactor is studied using a combination of particle image velocimetry and flow visualization. Shear‐thinning is found to alter the critical Reynolds numbers for the formation of Taylor vortices and the higher‐order wavy instability, and is associated with an increase in the axial wavelength. Strong shear‐thinning and weak viscoelasticity can also lead to sudden transitions in wavelength as the Reynolds number is varied. Finally, it is shown that shear‐thinning causes an increase in the mixing time within vortices, due to a reduction in their circulation, but enhances the axial dispersion of fluid in the reactor

    Health promotion in primary care: How should we intervene? A qualitative study involving both physicians and patients

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    <p>Abstract</p> <p>Background</p> <p>The effects of tobacco, physical exercise, diet, and alcohol consumption on morbidity and mortality underline the importance of health promotion and prevention (HPP) at the primary health care (PHC) level. Likewise, the deficiencies when putting such policies into practice and assessing their effectiveness are also widely recognised. The objectives of this research were: a) to gain an in-depth understanding of general practitioners' (GPs) and patients' perceptions about HPP in PHC, and b) to define the areas that could be improved in future interventions.</p> <p>Methods</p> <p>Qualitative methodology focussed on the field of health services research. Information was generated on the basis of two GP-based and two patient-based discussion groups, all of which had previously participated in two interventions concerning healthy lifestyle promotion (tobacco and physical exercise). Transcripts and field notes were analysed on the basis of a sociological discourse-analysis model. The results were validated by triangulation between researchers.</p> <p>Results</p> <p>GPs and patients' discourses about HPP in PHC were different in priorities and contents. An overall explanatory framework was designed to gain a better understanding of the meaning of GP-patient interactions related to HPP, and to show the main trends that emerged from their discourses. GPs linked their perceptions of HPP to their working conditions and experience in health services. The dimensions in this case involved the orientation of interventions, the goal of actions, and the evaluation of results. For patients, habits were mainly related to ways of life particularly influenced by close contexts. Health conceptions, their role as individuals, and the orientation of their demands were the most important dimensions in patients' sphere.</p> <p>Conclusions</p> <p>HPP activities in PHC need to be understood and assessed in the context of their interaction with the conditioning trends in health services and patients' social micro-contexts. On the basis of the explanatory framework, three development lines are proposed: the incorporation of new methodological approaches according to the complexity of HPP in PHC; the openness of habit change policies beyond the medical services; and the effective commitments in the medium to long term by the health services themselves at the policy management level.</p

    The CoDiNOS trial protocol: an international randomised controlled trial of intravenous sildenafil versus inhaled nitric oxide for the treatment of pulmonary hypertension in neonates with congenital diaphragmatic hernia

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    INTRODUCTION: Congenital diaphragmatic hernia (CDH) is a developmental defect of the diaphragm that impairs normal lung development, causing pulmonary hypertension (PH). PH in CDH newborns is the main determinant for morbidity and mortality. Different therapies are still mainly based on 'trial and error'. Inhaled nitric oxide (iNO) is often the drug of first choice. However, iNO does not seem to improve mortality. Intravenous sildenafil has reduced mortality in newborns with PH without CDH, but prospective data in CDH patients are lacking. METHODS AND ANALYSIS: In an open label, multicentre, international randomised controlled trial in Europe, Canada and Australia, 330 newborns with CDH and PH are recruited over a 4-year period (2018-2022). Patients are randomised for intravenous sildenafil or iNO. Sildenafil is given in a loading dose of 0.4 mg/kg in 3 hours; followed by continuous infusion of 1.6 mg/kg/day, iNO is dosed at 20 ppm. Primary outcome is absence of PH on day 14 without pulmonary vasodilator therapy and/or absence of death within the first 28 days of life. Secondary outcome measures include clinical and echocardiographic markers of PH in the first year of life. We hypothesise that sildenafil gives a 25% reduction in the primary outcome from 68% to 48% on day 14, for which a sample size of 330 patients is needed. An intention-to-treat analysis will be performed. A p-value (two-sided) <0.05 is considered significant in all analyses. ETHICS AND DISSEMINATION: Ethics approval has been granted by the ethics committee in Rotterdam (MEC-2017-324) and the central Committee on Research Involving Human Subjects (NL60229.078.17) in the Netherlands. The principles of the Declaration of Helsinki, the Medical Research Involving Human Subjects Act and the national rules and regulations on personal data protection will be used. Parental informed consent will be obtained. TRIAL REGISTRATION NUMBER: NTR6982; Pre-results

    Baseline characteristics of patients in the reduction of events with darbepoetin alfa in heart failure trial (RED-HF)

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    &lt;p&gt;Aims: This report describes the baseline characteristics of patients in the Reduction of Events with Darbepoetin alfa in Heart Failure trial (RED-HF) which is testing the hypothesis that anaemia correction with darbepoetin alfa will reduce the composite endpoint of death from any cause or hospital admission for worsening heart failure, and improve other outcomes.&lt;/p&gt; &lt;p&gt;Methods and results: Key demographic, clinical, and laboratory findings, along with baseline treatment, are reported and compared with those of patients in other recent clinical trials in heart failure. Compared with other recent trials, RED-HF enrolled more elderly [mean age 70 (SD 11.4) years], female (41%), and black (9%) patients. RED-HF patients more often had diabetes (46%) and renal impairment (72% had an estimated glomerular filtration rate &#60;60 mL/min/1.73 m2). Patients in RED-HF had heart failure of longer duration [5.3 (5.4) years], worse NYHA class (35% II, 63% III, and 2% IV), and more signs of congestion. Mean EF was 30% (6.8%). RED-HF patients were well treated at randomization, and pharmacological therapy at baseline was broadly similar to that of other recent trials, taking account of study-specific inclusion/exclusion criteria. Median (interquartile range) haemoglobin at baseline was 112 (106–117) g/L.&lt;/p&gt; &lt;p&gt;Conclusion: The anaemic patients enrolled in RED-HF were older, moderately to markedly symptomatic, and had extensive co-morbidity.&lt;/p&gt
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