Gene diversity among some endogamous population of Amravati District, Maharashtra, India.

The present work deals with the distribution of ABO, Rh and sickling alleles as markers to study the genetic structure and micro-demarcation among castes and tribal populations from the Amravati district of Maharashtra. Three loci namely, ABO, Rh and sickling were selected to measure the relative frequency of respective alleles in ten (10) endogamous populations inhabiting the Amravati District. The ABO locus was found to be less polymorphic when compared with other loci. On the other hand, Rh and sickling loci were found to be more polymorphic. Construction of a dendrogram using allele frequency data reveals an interesting relationship among the caste and tribe. An analysis shows three major clades comprising A, B and C. Clade A comprises Islamic Dawoodi Bohra and Hindu Gujrati. Clade B comprises the upper castes, Brahmin, Jain, Kashmiris and Kunbis, while Clade C shows Gonds and Katchhi. This study is a first attempt to provide a genetic landscape of castes and tribes inhabiting the Vidarbha region. The findings are discussed in light of the historical, anthropological and genetic data available for the studied group

Physiological Control of Human Heart Rate and Oxygen Consumption during Rhythmic Exercises

Physical exercise has significant benefits for humans in improving the health and quality of their lives, by improving the functional performance of their cardiovascular and respiratory systems. However, it is very important to control the workload, e.g. the frequency of body movements, within the capability of the individual to maximise the efficiency of the exercise. The workload is generally represented in terms of heart rate (HR) and oxygen consumption VO2. We focus particularly on the control of HR and VO2 using the workload of an individual body movement, also known as the exercise rate (ER), in this research. The first part of this report deals with the modelling and control of HR during an unknown type of rhythmic exercise. A novel feature of the developed system is to control HR via manipulating ER as a control input. The relation between ER and HR is modelled using a simple autoregressive model with unknown parameters. The parameters of the model are estimated using a Kalman filter and an indirect adaptive H1 controller is designed. The performance of the system is tested and validated on six subjects during rowing and cycling exercise. The results demonstrate that the designed control system can regulate HR to a predefined profile. The second part of this report deals with the problem of estimating VO2 during rhythmic exercise, as the direct measurement of VO2 is not realisable in these environments. Therefore, non-invasive sensors are used to measure HR, RespR, and ER to estimate VO2. The developed approach for cycling and rowing exercise predicts the percentage change in maximum VO2 from the resting to the exercising phases, using a Hammerstein model.. Results show that the average quality of fit in both exercises is improved as the intensity of exercise is increased

Quantum reverse-engineering and reference frame alignment without non-local correlations

Estimation of unknown qubit elementary gates and alignment of reference frames are formally the same problem. Using quantum states made out of $N$ qubits, we show that the theoretical precision limit for both problems, which behaves as $1/N^{2}$, can be asymptotically attained with a covariant protocol that exploits the quantum correlation of internal degrees of freedom instead of the more fragile entanglement between distant parties. This cuts by half the number of qubits needed to achieve the precision of the dense covariant coding protocol

Entanglement assisted alignment of reference frames using a dense covariant coding

We present a procedure inspired by dense coding, which enables a highly efficient transmission of information of a continuous nature. The procedure requires the sender and the recipient to share a maximally entangled state. We deal with the concrete problem of aligning reference frames or trihedra by means of a quantum system. We find the optimal covariant measurement and compute the corresponding average error, which has a remarkably simple close form. The connection of this procedure with that of estimating unitary transformations on qubits is briefly discussed.Comment: 4 pages, RevTeX, Version to appear in PR

The Phases and Triviality of Scalar Quantum Electrodynamics

The phase diagram and critical behavior of scalar quantum electrodynamics are investigated using lattice gauge theory techniques. The lattice action fixes the length of the scalar (``Higgs'') field and treats the gauge field as non-compact. The phase diagram is two dimensional. No fine tuning or extrapolations are needed to study the theory's critical behovior. Two lines of second order phase transitions are discovered and the scaling laws for each are studied by finite size scaling methods on lattices ranging from $6^4$ through $24^4$. One line corresponds to monopole percolation and the other to a transition between a ``Higgs'' and a ``Coulomb'' phase, labelled by divergent specific heats. The lines of transitions cross in the interior of the phase diagram and appear to be unrelated. The monopole percolation transition has critical indices which are compatible with ordinary four dimensional percolation uneffected by interactions. Finite size scaling and histogram methods reveal that the specific heats on the ``Higgs-Coulomb'' transition line are well-fit by the hypothesis that scalar quantum electrodynamics is logarithmically trivial. The logarithms are measured in both finite size scaling of the specific heat peaks as a function of volume as well as in the coupling constant dependence of the specific heats measured on fixed but large lattices. The theory is seen to be qualitatively similar to $\lambda\phi^{4}$. The standard CRAY random number generator RANF proved to be inadequateComment: 25pages,26figures;revtex;ILL-(TH)-94-#12; only hardcopy of figures availabl

Conservative treatment of spinal tuberculosis and its outcome: an observational study

Background: Spinal tuberculosis or Pott’s spine occurs in about 1-2% of patients with tuberculosis and accounts for 40-50% of musculoskeletal tuberculosis.It is caused due to the infection of the bone by Mycobacterium tuberculosis bacteria with the combination of spread through haematogenous route as well as lymphatic drainage.Methods: This observational study was done for a period of 2 years from Jan 2016 to Jan 2018. The total number of study participants was 51. The functional outcome was assessed using modified McCormick’s scale.Results: Majority of study participants were females accounting for 60.7% compared to males (39.21%). The main complaint of study participants was back pain (39.21%) which was followed by fever in 21.5%. Loss of appetite was the most prominent symptom seen in 15.6%. Thoracolumbar vertebrae were the site of involvement in 37.2%.Conclusions: Patients responded well with anti-tubercular treatment in mild and moderate cases of spinal TB, if there was no gross neurological deficit. Thus it is very important to identify the early symptoms of spinal TB so that timely prompt treatment should be initiated

ABO and Rh Blood Group Distribution Among Kunbis (Maratha) population of Amravati District, Maharashtra

The present study reports the distribution of ABO and Rh blood groups among the Kunbis (Maratha) population of Amravati district. The phenotypic frequency of blood group B is observed highest (33.06) percent, O (31.04), A (27.02) and AB is lowest (08.33) percent. The phenotypic frequency of Rh negative is (04.26) percent. TheKunbis (Maratha) population shows close genetic relationship with the Gujratis

Can clinical staging of primary amoebic meningoencephalitis be of any therapeutic benefit

Naegleria fowleri, is a free-living amoeba (FLA) known to infect humans and cause a fatal disease called primary amoebic meningoencephalitis (PAM). All of the patients are commonly admitted to the emergency room (ER). Often, treatment in the ER is delayed due to the rarity of disease leading to a delay in the diagnosis and late arrival of patients to the ER. The attempts to reduce raised intracranial pressure and subsequent herniation of the brain stem are challenging and become the cause of death in the affected patients during their stay in ER. Use of drugs like mannitol to reduce raised intra-cerebral pressure (ICP) could prove dangerous in the presence of cerebral haemorrhage and this fact could be overlooked during the management of patients with PAM. No precise therapy is followed for PAM, and most often a course of broad spectrum anti-protozoal drugs is employed. A CDC recommended drug miltefosine has show success in early diagnosed cases. So far, there is no clinical staging of PAM, and patients are managed for the complications that develop while their stay in the ER. Given the health scare associated with N. fowleri in countries with tropical climates, and its potential ability to cause severe meningoencephalitis that often progresses to lethal outcomes, we believe it is imperative to stage PAM into clear progressive stages to help its management in the ER and debate its therapeutic gains. Such a clinical staging could aid in efforts to diagnose and treat PAM. Furthermore, it will help in raising public awareness, in educating healthcare and allied personne

Secrecy content of two-qubit states

We analyze the set of two-qubit states from which a secret key can be extracted by single-copy measurements plus classical processing of the outcomes. We introduce a key distillation protocol and give the corresponding necessary and sufficient condition for positive key extraction. Our results imply that the critical error rate derived by Chau, Phys. Rev. A {\bf 66}, 060302 (2002), for a secure key distribution using the six-state scheme is tight. Remarkably, an optimal eavesdropping attack against this protocol does not require any coherent quantum operation.Comment: 5 pages, RevTe