Hotel or rented flat: A profile of purchasers of accommodation services in Warsaw

The spreading of short-term flat rentals has brought about changes in the accommodation market, often seen as a threat to traditional accommodation providers. This is particularly true in large cities which have a considerable accommodation capacity and also a large stock of flats. The aim is to indicate to what extent short-term rentals are influencing the tourist accommodation market in Warsaw. The idea behind the study is the assumption that the differences revealed between those using hotels or such flats will provide an answer to the question of the influence of the latter on Warsaw»s tourist market. Such information should be useful in the marketing activities of interested parties and in the policies of the city authorities. Analysis of the data from a survey carried out in 2021 using the CHAID decision tree indicates that the choice of accommodation type was mainly determined by situational variables. The only statistically significant demographic predictor relates to a greater interest in flats among those aged up to 34 years old. Planned expenditure per person per overnight stay proved to be a statistically significant predictor only for non-residents of Poland, with the cut-off amount set higher than the median interval for this segment. Flats were more often chosen by people travelling in a larger party or alone and those planning to stay longer than four nights, thus looking for a different offer than that of traditional city hotels

Integration of Cryopreservation and Tissue Culture for Germplasm Conservation and Propagation of Rosa pomifera ‘Karpatia’

Cryopreservation is an useful technique for long-term conservation that requires minimal space and maintenance. Germplasm protection of Rosa is important to preserve genetic diversity, to store material for breeding and to expand new research. This study was conducted to develop a droplet vitrification cryopreservation and micropropagation of Rosa pomifera cv. ‘Karpatia’, whose large hypanthia are characterized by remarkable pro-health properties. Culture in vitro was stabilized and shoot tips collected from dormant buds served as initial explants. The multiplication of shoots was carried out on MS medium containing benzyladenine. For the droplet vitrification cryopreservation, shoot tips from in vitro cultures were used: small with exposed meristem, and large with a meristem covered with leaves, as well as shoot tips from in situ plants, which were collected in winter. Treatment time with plant vitrification solution (PVS2) was also tested (10-30 minutes). From in vitro culture, 32-41% small explants with exposed meristem survived, but they regenerated at a very low level. The best cryostorage results were obtained for shoot tips from dormant buds and a 20-minute PVS2 treatment: the survival was 84% and regeneration 72%. During the post-freezing regeneration multiplication index was 2.4 shoots per one multiplication cycle, after cryopreservation and in the control. On half MS medium without growth regulators, 97-99% of shoots rooted, and all rooted plants have adapted to ex vitro conditions and were planted into the soil. Biometric analyses during shoot multiplication, rooting and acclimatization stages did not reveal any changes compared to the non-cryopreserved samples

Perceived Loneliness in Children with and without Type 1 Diabetes: A Cross-Sectional Study

Objective: To assess perceived loneliness in children with type 1 diabetes (T1D) and children without diabetes. Material and methods: The study comprised 165 children without and 174 children with type 1 diabetes. Children’s Loneliness and Social Dissatisfaction Scale (CLS) was used to assess the sense of loneliness in children aged 10–13 years and Revised UCLA Loneliness Scale (R-UCLA) in children aged 14–17 years. Metric variables for children included: gender, age, place of residence, type of school, frequency of school absences per year, number of annual medical appointments. A χ2 test was used to compare the study group results. The non-parametric Mann-Whitney U-test was used to assess differences in one variable between the two groups. Results: In the group of children aged 10–13 years, overall, a slightly higher score was obtained by children without diabetes, compared to children with diabetes (p = 0.387). The R-UCLA scale, also showed a higher mean value in the group of adolescents without diabetes compared to adolescents with diabetes (p = 0.177). Adolescents without diabetes scored significantly higher on the Intimate Others subscale (p = 0.026). Conclusions: Children with T1D had a similar perception of loneliness to children without diabetes. Cliniciansworking with children should assess a child’s perception of loneliness during appointments. Further research is needed into the perception of loneliness in children and adolescents with and without diabetes, with commonly used measures of loneliness to enable their use in clinical practice as screening tools and to evaluate actions taken

Pro Libris: Lubuskie Pismo Literacko-Kulturalne, nr 3 (2011)

175 s. : il.

Samotność, lęk i depresja wśród pacjentów z padaczką

Introduction. Epilepsy is one of the most common neurological disorders. The unpredictability of epileptic seizures can lead to feelings of loneliness, social isolation and stigmatisation. Due to the nature of this syndrome, patients may also show symptoms of depression. Aim. The aim of the study was to determine the prevalence of anxiety, depression and loneliness, and the relationship between loneliness and depression among adult patients with epilepsy. Material and Methods. This was a cross-sectional, observational study. A total of 206 patients with epilepsy participated in the study. The study was conducted using a website dedicated for persons with epilepsy. Data was collected from November 2021 to March 2022. Two research tools were used in the study: DeJong Gierveld Loneliness Scale (DJGLS) and the Hospital Anxiety and Depression Scale (HADS-M) and an author-developed demographic questionnaire to characterise the study group. Results. The prevalence of depressive symptoms and borderline abnormalities was 51.5%, 22.8%, respectively. In the depression subscale, 48.1% of the respondents had depressive symptoms and 22.1% had borderline abnormalities. The anxiety and irritability subscales showed disorders in 34.5% and 69.4% of the respondents, respectively. A very high and high level of loneliness was found in 17% and 26% of respondents, respectively. A moderate level of loneliness was reported by 40% of respondents. In terms of emotional loneliness, severe and moderate loneliness affected 52% and 21% of respondents, while severe and moderate social loneliness was reported by 41% and 28% of respondents. Conclusions. The study showed relatively high levels of loneliness and depressive symptoms. A significant correlation was found between the level of loneliness and the intensity of depressive symptoms. (JNNN 2023;12(1):34–43)Wstęp. Padaczka jest jednym z najczęstszych schorzeń neurologicznych. Nieprzewidywalność napadów epilepsji może doprowadzić do poczucia samotności, izolacji społecznej oraz stygmatyzacji. Ze względu na charakter tego zespołu chorobowego pacjenci mogą manifestować objawy depresji. Cel. Celem badania było określenie częstości występowania lęku, objawów depresji i poczucia samotności oraz zależności pomiędzy samotnością a depresją wśród dorosłych pacjentów z padaczką. Materiał i metody. Było to przekrojowe badanie obserwacyjne. W badaniu wzięło udział 206 osób cierpiących z powodu padaczki. Badanie było zrealizowane przy użyciu strony internetowej, w grupie zrzeszającej pacjentów z padaczką. Dane zbierano od listopada 2021 r. do marca 2022 r. Do przeprowadzenia badania wykorzystano dwa standaryzowane narzędzia badawcze: skalę pomiaru poczucia samotności autorstwa de Jong Gierveld (DJGLS) oraz Szpitalną Skala Lęku i Depresji (HADS-M) — Hospital Anxiety and Depression Scale i metryczkę własnego autorstwa charakteryzującą badaną grupę. Wyniki. Częstość występowania objawów depresji wśród badanych wynosiła 51,5%, u 22,8% stwierdzono stany graniczne. W podskali depresji u 48,1% badanych występowały objawy depresji, u 22,1% stany graniczne. W podskali lęku występowanie zaburzeń zanotowano u 34,5% badanych, natomiast w podskali rozdrażnienia u 69,4% osób. Bardzo poważny i poważny poziom samotności odczuwało (17%, 26%) badanych. U 40% zaobserwowano umiarkowany poziom samotności. W zakresie samotności emocjonalnej z powodu poważnej i umiarkowanej samotności cierpiało (52%, 21%) badanych, natomiast z powodu poważnej i umiarkowanej samotności społecznej (41%, 28%) osób. Wnioski. W badaniu uzyskano dość wysokie wyniki w zakresie poziomu samotności i częstości występowania objawów depresji. Stwierdzono istotną zależność pomiędzy poziomem samotności a natężeniem objawów depresji. (PNN 2023;12(1):34–43

A new detector concept based on the prompt gamma radiation analysis for In vivo boron monitoring in BNCT

The problem of boron concentration monitoring during the boron neutron capture therapy (BNCT) therapy is one of the main challenges of this type of radiotherapy and is directly related to the nature of the interaction of neutrons with mater. Among the available in vivo methods of boron monitoring positron emission tomography seems to be very promising but it requires a new boron carrier with a β+ emitter, which is not yet clinically available. An alternative solution may be the prompt gamma radiation analysis (PGRA) based on the secondary radiation emitted in the interaction of neutrons with the patient’s tissues. This method requires, however, compact gamma radiation detection systems sustaining high counting rates and characterized by very good energy resolution. In this contribution, we present state-of-the-art solutions for monitoring in BNCT based on PGRA. Moreover, we describe a new concept of such a system based on position-sensitive scintillator detectors equipped with an anti-Compton shield and data analysis supported with modern artificial intelligence algorithms

Pro Libris: Lubuskie Pismo Literacko-Kulturalne, nr 4 (2011)

142 s. : il

Przezczaszkowa ultrasonografia dopplerowska (TCD) u chorych z poszerzonym układem komorowym : poszukiwanie dodatkowych wskaźników kwalifikacji do zabiegu implantacji układu zastawkowego

Background: Ventriculomegaly without increased intracranial pressure is observed both in normal-pressure hydrocephalus (NPH) and idiopathic cerebral atrophy (CA). Investigating additional parameters to differentiate these diseases is important for a good qualification of shunt implantation. The study presents the influence of intravenous administration of acetazolamide on cerebral blood flow velocity (BFV) and cerebrovascular reactivity (CVR) in 23 patients with ventriculomegaly and symptoms of cognitive function disorders. The aim was to establish the differences in the dynamic cerebral hemodynamics parameters in NPH and CA patients. Material/Methods: Measurement of BFV was performed in 23 patients using transcranial Doppler (TCD) ultrasonography before and 20 minutes after intravenous administration of 1000 mg acetazolamide. CVR was calculated as the percent change from the baseline mean BFV value and assessed bilaterally in the middle (MCA), anterior (ACA), posterior (PCA), and internal carotid cerebral (ICA) arteries in the intracranial part. Additionally, BFV was evaluated in selected patients during a lumbar infusion test. The patients were divided into 2 groups: those with NPH and those with CA. Results: BFV values were decreased both in the NPH and the CA group compared with the control group (healthy volunteers of the same age). There were no significant differences between the two groups. In the CA group a complete lack of CVR was observed in all examined arteries. In the NPH group, CVR was maintained, while mean BFV (MFV) changed 37±4% in the MCA, 26±6% in the ACA, 33±5% in the PCA, and 30±4% in the ICA. There were statistically significant differences in CVR values between the groups. A decrease in initial BFV in all examined intracranial arteries and a complete lack of CVR is characteristic of the CA group. Conclusions: Maintenance of CVR and a simultaneous decrease in BFV is a characteristic of the NPH group, but among the patients in that group we found differences in cerebrovascular response to acetozolamide, In both groups there were no significant differences in BFV in the MCA during the lumbar infusion test. The acetazolamide test appears as an additional factor in the differential diagnosis of NPH and CA

Detection of a second primary cancer in a 18F-fluorocholine PET/CT – multicentre retrospective analysis on a group of 1345 prostate cancer patients

Background: Aim of this study was to evaluate the rate of incidental detection of second primary cancer (SPC) at 18F-fluorocholine ([18F]FCH) positron emission tomography/computed tomography (PET/CT) performed in prostate cancer patients. Material and methods: A retrospective analysis was performed on a group of 1345 prostate cancer patients, who underwent [18F]FCH PET/CT study because of suspicion of recurrence (n = 937) or for initial staging (n = 408). Images were acquired after intravenous injection [18F]FCH with a mean activity of 200 ± 75 MBq (5.4 ± 2 mCi), from the top of the head to the half of the thigh. The confirmation of second primary cancer was obtained from the cancer registry. Results: Based on the [18F]FCH PET/CT scans, a second primary cancer was suspected in 89 patients (6.6%). Of these, a malignancy was histologically confirmed in 26 patients (29% of all suspected findings and 1.9% of the complete cohort). Lung cancer (including adenocarcinoma, neuroendocrine cancer) was diagnosed in 13 patients (50%) and hematologic neoplasm (including chronic lymphocytic leukemia, Hodgkin lymphoma, follicular lymphoma, and multiple myeloma) in 5 patients (19%). 18F-fluorocholine PET/CT also revealed esophageal cancer, mesothelioma, testicular, renal, bladder, and colorectal cancer inindividual patients, non-keratinizing squamous cell carcinoma (SCC) of the skin as well as head and neck SCC with unknown primary. Conclusion: We conclude that incidental detection of a second primary cancer in prostate cancer patients using [18F]FCH PET/CT is not very common and that lung cancer and hematologic malignancies are most frequently detected