19 research outputs found

    Взаимосвязь пальцевого индекса и развития предметно-познавательных способностей школьников

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    В настоящее время уделяют серьезное внимание антропологическому исследованию. Нами проведено исследование пальцевого индекса у школьников старших классов. В исследовании принимали участие 24 школьника, из них мальчиков - 10 и девочек - 14; средний возраст - 14,5 лет. Оказалось, что у большинства мальчиков пальцевой индекс ниже единицы. Школьницы с пальцевым индексом единица и выше единицы учатся лучше, занимаются активно спортом, интересуются танцами и музыкой. Однако, достоверной зависимости успехов по русскому языку от пальцевого индекса у школьников не обнаружено. Возможно, полученные данные связаны с маленькой выборкой исследуемого материал

    Research of biochemical gold recovery method using high-arsenic raw materials

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    This article contains the results of experiments to recover gold from complex mineral raw materials containing more than 15 % arsenic. Laboratory tests showed that standard cyanidation recovers only 26,4 % of gold into the solution. Additional oxidizing reagents used increase the leaching efficiency and enable to recover more than 40 % of gold during subsequent cyanidation. The efficiency has been established for replacement of cyanide with thiourea and thiosulfate solutions. 79,5 %, i.e. the maximum recovery rate, was found in the experiment with preliminary oxidation with T. Ferrooxidans, a bacterial culture, followed by leaching with a thiourea solution

    Stimulation of lymphocyte anti-melanoma activity by co-cultured macrophages activated by complex homeopathic medication

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    <p>Abstract</p> <p>Background</p> <p>Melanoma is the most aggressive form of skin cancer, and the most rapidly expanding cancer in terms of worldwide incidence. Chemotherapeutic approaches to treat melanoma have been uniformly disappointing. A Brazilian complex homeopathic medication (CHM), used as an immune modulator, has been recommended for patients with depressed immune systems. Previous studies in mice have demonstrated that the CHM activates macrophages, induces an increase in the number of leukocytes and improves the murine response against Sarcoma-180.</p> <p>Methods</p> <p>Here we studied the interaction of mouse lymph node lymphocytes, co-cultured <it>in vitro </it>with macrophages in the presence or absence of the CHM, with B16F10 melanoma cells.</p> <p>Results</p> <p>Lymphocytes co-cultured with macrophages in the presence of the CHM had greater anti-melanoma activity, reducing melanoma cell density and increasing the number of lysed tumor cells. There was also a higher proportion of activated (CD25<sup>+</sup>) lymphocytes with increased viability. Overall, lymphocytes activated by treatment destroyed growing cancer cells more effectively than control lymphocytes.</p> <p>Conclusion</p> <p>Co-culture of macrophages with lymphocytes in the presence of the CHM enhanced the anti-cancer performance of lymphocytes against a very aggressive lineage of melanoma cells. These results suggest that non-toxic therapies using CHMs are a promising alternative approach to the treatment of melanomas. In addition, they are attractive combination-therapy candidates, which may enhance the efficacy of conventional medicines by improving the immune response against tumor cells.</p

    Doing synthetic biology with photosynthetic microorganisms

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    The use of photosynthetic microbes as synthetic biology hosts for the sustainable production of commodity chemicals and even fuels has received increasing attention over the last decade. The number of studies published, tools implemented, and resources made available for microalgae have increased beyond expectations during the last few years. However, the tools available for genetic engineering in these organisms still lag those available for the more commonly used heterotrophic host organisms. In this mini-review, we provide an overview of the photosynthetic microbes most commonly used in synthetic biology studies, namely cyanobacteria, chlorophytes, eustigmatophytes and diatoms. We provide basic information on the techniques and tools available for each model group of organisms, we outline the state-of-the-art, and we list the synthetic biology tools that have been successfully used. We specifically focus on the latest CRISPR developments, as we believe that precision editing and advanced genetic engineering tools will be pivotal to the advancement of the field. Finally, we discuss the relative strengths and weaknesses of each group of organisms and examine the challenges that need to be overcome to achieve their synthetic biology potential.Peer reviewe
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