Rumpel-Leede phenomenon following radial artery catheterisation

Rumpel-Leede phenomenon is a rarely diagnosed entity that can be seen in patients following the application of tourniquet-like forces to the extremities. This phenomenon describes petechiae and purpura secondary to venous compression and congestion, with its underlying aetiology involving the fragility of capillary vessels within the dermis. This condition is associated with chronic medical conditions such as diabetes mellitus, hypertension, dyslipidemia, peripheral vascular disease and systemic inflammatory diseases, including infections. In addition, patients with coagulopathy including thrombocytopenia or platelet dysfunction from antiplatelet use, or those with thrombotic thrombocytopenic purpura and idiopathic thrombocytopenic purpura, are predisposed to capillary haemorrhage and petechiae formation. In this report, we present a case of a patient who developed Rumpel-Leede phenomenon following catheterisation of the right radial artery with spontaneous resolution – where only five cases have been reported to date – with the aim to make clinicians aware of this condition and to avoid unnecessary interventions

Portrait Landscapes

Portrait Landscapes builds on Passing Between and Dynamic Stasis, the two previous collaborations between professors Dr. Nathaniel Stern and Jessica Meuninck-Ganger, in which traditional and contemporary art forms are juxtaposed by mounting translucent prints and drawings directly on top of video screens to create moving images on paper. The results expand our understanding of these disparate practices, question conventions of image making, augment the narrative on the history of art and media, and create a complexity that engages the audience, not as passive viewers, but empowered coauthors of the works’ meaning. It is exactly this complexity that Portrait Landscapes investigates in a forthcoming series that features a diverse group of local leaders; challenging the artists, the subjects, and the viewers to look beyond the surface, even reconsider the concept of a surface in the works of art and in our subjects. Through a series of audio-recorded interviews, each subject answered questions about who they are, who they are known to be, why they are, how they came to be, which informed our decision of where to shoot video documentation of them and what activity they would perform in the video. Silent, edited versions of the video are played on loop on LCD digital screens, which are then overlaid with a print or drawing that feature visual elements from the video but is highly influenced by the content of the original audio interview. Each work is completed with a short biography and a title card, both of which feature varying self-reflections of the subject, resulting in a portrait that represents our subjects in a deeper and more multifaceted way than any single medium or depiction could achieve. Perhaps the most significant findings at this stage of the process are the manifold paths to the various conceptions and manifestations of leadership experienced and evidenced by our subjects, exploring and challenging notions of self, community, family, service, passion, compassion, and justice, and additionally representing all of these ideas and more in a portrait of an individual. Society is saturated with acronyms, truncated words, character limits, avatars, symbols, and never-ending upgrades. Portrait Landscapes stands opposed to consolidation, generalization, and simplification under the guise of convenience, and acknowledges that true understanding requires time, effort, and willingness to explore from multiple vantage points. Championing diversity in all of its forms, Portrait Landscapes stands as a model of how to see and be in this world

Spent Coffee Grounds Applied as a Top-Dressing or Incorporated into the Soil Can Improve Plant Growth While Reducing Slug Herbivory

Between 8 and 15 million tons of spent coffee grounds (SCG) are produced as global waste each year. To reduce waste to landfill, SCG are proposed as a carbon and nutrient source for degraded soils. SCG contain caffeine and other toxins that inhibit plant growth. However, they also repel slugs and snails. We examined whether partial decomposition can neutralize SCG to promote plant growth while maintaining anti-herbivore properties. We aged SCG for Hermetia illucens) frass. The aged SCG and frass were applied, either incorporated into soil or as a 1 cm top-dressing, to pots with radish and tomato seedlings. SCG treatments were also examined for direct (repellent) and indirect (plant-mediated) effects on four slug species (Arion ater, Deroceras laeve, Derocerus reticulatum and Lehmannia marginata). SCG of ≤7 months inhibited plant growth and development and reduced herbivory when incorporated into soil, whereas 14-month-old SCG promoted growth but had no effect on herbivory. When applied as a top-dressing, SCG at 7 months promoted growth and reduced herbivory through repellent and host quality effects—including possible systemic effects. Our results indicate that the benefits of SCG for radish and tomato growth and to reduce slug herbivory can be achieved simultaneously by applying partially decomposed SCG (aged for up to 8 months) as a top-dressing

Managing Sexually Harmful Behaviour in a Residential Special School

Accessible summary Children and young people with learning disabilities who present sexually harmful behaviour are often not allowed into the community. This study describes the work carried out with a boy with sexually harmful behaviour attending a residential special school. The staff helped teach the boy how to behave in social situations and about sex, consent and relationships. Afterwards, the boy was able to participate in supervised community activities. Summary Children and young people with learning disabilities who present sexually harmful behaviour are marginalised and do not always participate in community activities. This case study describes a multi-component intervention that successfully reduced the sexually harmful behaviour of a 16-year-old boy with a mild learning disability. The intervention was comprised of cognitive behaviour therapy, Social Stories™ and a behavioural programme that reinforced appropriate behaviour with social praise and access to preferred items and a range of community activities. Following the intervention, he was able to participate in a wide range of supervised community activities

Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells

Specialized proresolving mediators (SPMs) actively limit inflammation and expedite its resolution by modulating leukocyte recruitment and function. Here we profiled intramuscular lipid mediators via liquid chromatography-tandem mass spectrometry–based metabolipidomics following myofiber injury and investigated the potential role of SPMs in skeletal muscle inflammation and repair. Both proinflammatory eicosanoids and SPMs increased following myofiber damage induced by either intramuscular injection of barium chloride or synergist ablation–induced functional muscle overload. Daily systemic administration of the SPM resolvin D1 (RvD1) as an immunoresolvent limited the degree and duration of inflammation, enhanced regenerating myofiber growth, and improved recovery of muscle strength. RvD1 suppressed inflammatory cytokine expression, enhanced polymorphonuclear cell clearance, modulated the local muscle stem cell response, and polarized intramuscular macrophages to a more proregenerative subset. RvD1 had minimal direct impact on in vitro myogenesis but directly suppressed myokine production and stimulated macrophage phagocytosis, showing that SPMs can modulate both infiltrating myeloid and resident muscle cell populations. These data reveal the efficacy of immunoresolvents as a novel alternative to classical antiinflammatory interventions in the management of muscle injuries to modulate inflammation while stimulating tissue repair

One thousand plant transcriptomes and the phylogenomics of green plants

Abstract: Green plants (Viridiplantae) include around 450,000–500,000 species1, 2 of great diversity and have important roles in terrestrial and aquatic ecosystems. Here, as part of the One Thousand Plant Transcriptomes Initiative, we sequenced the vegetative transcriptomes of 1,124 species that span the diversity of plants in a broad sense (Archaeplastida), including green plants (Viridiplantae), glaucophytes (Glaucophyta) and red algae (Rhodophyta). Our analysis provides a robust phylogenomic framework for examining the evolution of green plants. Most inferred species relationships are well supported across multiple species tree and supermatrix analyses, but discordance among plastid and nuclear gene trees at a few important nodes highlights the complexity of plant genome evolution, including polyploidy, periods of rapid speciation, and extinction. Incomplete sorting of ancestral variation, polyploidization and massive expansions of gene families punctuate the evolutionary history of green plants. Notably, we find that large expansions of gene families preceded the origins of green plants, land plants and vascular plants, whereas whole-genome duplications are inferred to have occurred repeatedly throughout the evolution of flowering plants and ferns. The increasing availability of high-quality plant genome sequences and advances in functional genomics are enabling research on genome evolution across the green tree of life

Coronal Heating as Determined by the Solar Flare Frequency Distribution Obtained by Aggregating Case Studies

Flare frequency distributions represent a key approach to addressing one of the largest problems in solar and stellar physics: determining the mechanism that counter-intuitively heats coronae to temperatures that are orders of magnitude hotter than the corresponding photospheres. It is widely accepted that the magnetic field is responsible for the heating, but there are two competing mechanisms that could explain it: nanoflares or Alfv\'en waves. To date, neither can be directly observed. Nanoflares are, by definition, extremely small, but their aggregate energy release could represent a substantial heating mechanism, presuming they are sufficiently abundant. One way to test this presumption is via the flare frequency distribution, which describes how often flares of various energies occur. If the slope of the power law fitting the flare frequency distribution is above a critical threshold, $\alpha=2$ as established in prior literature, then there should be a sufficient abundance of nanoflares to explain coronal heating. We performed $>$600 case studies of solar flares, made possible by an unprecedented number of data analysts via three semesters of an undergraduate physics laboratory course. This allowed us to include two crucial, but nontrivial, analysis methods: pre-flare baseline subtraction and computation of the flare energy, which requires determining flare start and stop times. We aggregated the results of these analyses into a statistical study to determine that $\alpha = 1.63 \pm 0.03$. This is below the critical threshold, suggesting that Alfv\'en waves are an important driver of coronal heating.Comment: 1,002 authors, 14 pages, 4 figures, 3 tables, published by The Astrophysical Journal on 2023-05-09, volume 948, page 7