Black-box modeling of nonlinear system using evolutionary neural NARX model

Nonlinear systems with uncertainty and disturbance are very difficult to model using mathematic approach. Therefore, a black-box modeling approach without any prior knowledge is necessary. There are some modeling approaches have been used to develop a black box model such as fuzzy logic, neural network, and evolution algorithms. In this paper, an evolutionary neural network by combining a neural network and a modified differential evolution algorithm is applied to model a nonlinear system. The feasibility and effectiveness of the proposed modeling are tested on a piezoelectric actuator SISO system and an experimental quadruple tank MIMO system

Первое сообщение об Auerbachia chakravartyi (Myxosporea: Bilvavulida) из желчного пузыря Megalaspis cordyla во Вьетнаме

В 2017 г. в Тонкинском заливе было исследовано 20 экз. Megalaspis cordyla. Морфологическими и молекулярно-биологическими методами было установлено наличие в желчном пузыре 7 из 20 рыб (35 %) спор Auerbachia chakravartyi Narasimhamurti, Kalavati, Anuradha, Padma, 1990. Это первая находка представителей рода Auerbachia в морских рыбах Вьетнама

Copper Ferrite Superparamagnetic Nanoparticle-Catalyzed Cross-coupling Reaction to Form Diindolylmethane (DIM): Effect of Experimental Parameters

Superparamagnetic copper ferrite (CuFe2O4) nanoparticles were utilized as a heterogenous catalyst for the cross-coupling reaction of indole to form 3,3’-diindolylmethane (DIM) as the desirable product. High reaction yield, at around 82%, was achieved under optimal conditions. The CuFe2O4 material could be easily separated from the reaction mixture by an external magnetic field and could be reutilized several times without a significant decrease in catalytic activity. We also showed that no sites of catalyst material leached into reaction solution was detected. To our best knowledge, the above cross-coupling reaction was not previously conducted under catalysis of superparamagnetic nanoparticles. Copyright © 2021 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0)

Hochpräzise CNC-Roboter für die additive Fertigung von Faserverbundstrukturen

Die Steigerung von Nachhaltigkeit und Produktivität zählt zu den großen Aufgaben dieser Zeit. In der Industrie besteht daher Bedarf an präzisen und flexiblen Anlagen für die additive Fertigung. An unserem Institut kommen hierfür speziell konzipierte CNC-Roboterkinematiken zum Einsatz. In Kombination mit gezielt entwickelten Werkzeugen zur Ablage kurz- und endlosfaserverstärkter Materialien entsteht ein agiler und flexibler Prozess zur additiven Fertigung thermoplastischer Faserverbundstrukturen

Environmentally Responsible Bioengineering for Spore Surface Expression of Helicobacter pylori Antigen

The development of genetic technologies and bioengineering are creating an increasing number of genetically engineered microorganisms with new traits for diverse industrial applications such as vaccines, drugs and pollutant degraders. However, the destiny of genetically engineered bacterial spores released into the environment as long-life organisms has remained a big environmental challenge. In this study, an environmentally responsible and sustainable gene technology solution based on the concept of thymine starvation is successfully applied for cloning and expression of a Helicobacter pylori antigen on Bacillus subtilis spore surface. As an example, a recombinant Bacillus subtilis strain A1.13 has been created from a gene fusion of the corresponding N-terminal fragment of spore coat protein CotB in B. subtilis and the entire urease subunit A (UreA) in H. pylori and the fusion showed a high stability of spore surface expression. The outcomes can open the door for developing highly safe spore vectored vaccines against this kind of pathogen and contributing to reduced potential risks of genetically engineered microorganisms released in the environment

Extraction of anthocyanins from Butterfly pea (Clitoria ternatea L. Flowers) in Southern Vietnam: Response surface modeling for optimization of the operation conditions

In this paper, the Response Surface Methodology (RSM), in conjunction with Central Composite Design (CCD), was used to optimize the extraction of anthocyanins from Butterfly pea (Clitoria ternatea L.Flowers) cultivated in Southern Vietnam. The effect of extraction temperatures of solvent ethanol (50-70 °C), duration of extraction (40-50 min) and solid-liquid ratios (20:1-30:1) was measured as independent variables on the total extraction anthocyanins in the response function. The highest anthocyanin content of 132.756 mg/L of butterfly pea anthocyanin was collected at the solid liquid ratio of 23:1, extraction time of 46 min, and temperature 60.6°C. Butterfly pea anthocyanins yield detailed significant correlation with high F values, low P values (<0.0001), and desirable determination coefficient (R2 = 0.9994)

Synthesis of new simplified hemiasterlin derivatives with α,β-unsaturated carbonyl moiety.

International audienceIn this Letter, we report a convenient and efficient method for the synthesis of new simplified derivatives of hemiasterlin in which the α,α-dimethylbenzylic moiety A is replaced by α,β-unsaturated aryl groups as Michael acceptor. Most of these derivatives have a strong cytotoxic activity on three human tumor cell lines (KB, Hep-G2 and MCF7). Analogs 17b and 17f showed a high cytotoxicity against KB and Hep-G2 cancer cell lines comparable to paclitaxel and ellipticine

Synthesis of new bioisosteric hemiasterlin analogues with extremely high cytotoxicity

International audienceIn this article, we report a convenient and efficient method for the synthesis of new simplified derivativesof hemiasterlin in which the α,α-dimethylbenzylic moiety A is replaced by α,β-unsaturated aryl groupsas Michael acceptor. Most of these derivatives have a strong cytotoxic activity on three human tumorcell lines (KB, Hep-G2 and MCF7). Analogs 17b and 17f showed a high cytotoxicity against KB andHep-G2 cancer cell lines comparable to paclitaxel and ellipticine

Analytical study of the sth-order perturbative corrections to the solution to a one-dimensional harmonic oscillator perturbed by a spatially power-law potential Vper(x) = λxα

In this work, we present a rigorous mathematical scheme for the derivation of the sth-order perturbative corrections to the solution to a one-dimensional harmonic oscillator perturbed by the potential V-per(x) = lambda x(alpha), where alpha is a positive integer, using the non-degenerate time-independent perturbation theory. To do so, we derive a generalized formula for the integral I = integral(+infinity)(-infinity)x(alpha)exp(-x(2))H-n(x)H-m(x)d(x), where H-n(x) denotes the Hermite polynomial of degree n, using the generating function of orthogonal polynomials. Finally, the analytical results with alpha = 3 and alpha = 4 are discussed in detail and compared with the numerical calculations obtained by the Lagrange-mesh method