9,791 research outputs found
Nitrous oxide in fresh water systems: An estimate for the yield of atmospheric N2O associated with disposal of human waste
The N2O content of waters in the Potomac and Merrimack Rivers was measured on a number of occasions over the period April to July 1977. The concentrations of dissolved N2O exceeded those which would apply in equilibrium with air by factors ranging from about 46 in the Potomac to 1.2 in the Merrimack. Highest concentrations of dissolved N2O were associated with sewage discharges from the vicinity of Washington, D. C., and analysis indicates a relatively high yield, 1.3 to 11%, for prompt conversion of waste nitrogen to N2O. Measurements of dissolved N2O in fresh water ponds near Boston demonstrated that aquatic systems provide both strong sources and sinks for atmospheric N2O
Geometry dependence of the clogging transition in tilted hoppers
We report the effect of system geometry on the clogging of granular material
flowing out of flat-bottomed hoppers with variable aperture size D. For such
systems, there exists a critical aperture size Dc at which there is a
divergence in the time for a flow to clog. To better understand the origins of
Dc, we perturb the system by tilting the hopper an angle Q and mapping out a
clogging phase diagram as a function of Q and D. The clogging transition
demarcates the boundary between the freely-flowing (large D, small Q) and
clogging (small D, large Q) regimes. We investigate how the system geometry
affects Dc by mapping out this phase diagram for hoppers with either a circular
hole or a rectangular narrow slit. Additionally, we vary the grain shape,
investigating smooth spheres (glass beads), compact angular grains (beach
sand), disk-like grains (lentils), and rod-like grains (rice). We find that the
value of Dc grows with increasing Q, diverging at pi-Qr where Qr is the angle
of repose. For circular apertures, the shape of the clogging transition is the
same for all grain types. However, this is not the case for the narrow slit
apertures, where the rate of growth of the critical hole size with tilt angle
depends on the material
Size segregation and convection
The size segregation of granular materials in a vibrating container is
investigated using Molecular Dynamics. We find that the rising of larger
particles is accompanied by the existence of convection cells even in the case
of the lowest possible frequencies. The convection can, however, also be
triggered by the larger particle itself. The possibility of rising through this
mechanism strongly depends on the depth of the larger particle.Comment: 7 pages, 4 figure
The Photometric Variability of HH 30
This is the final version. Available from Universidad Nacional Autónoma de México via the link in this recordHH 30 is an edge-on disk around a young stellar object. Previous imaging with the Hubble Space Telescope has shown morphological variability that is possibly related to the rotation of the star or the disk. We report the results of two terrestrial observing campaigns to monitor the integrated magnitude of HH 30. We use the Lomb-Scargle periodogram to look for periodic modulation with periods between 2 days and almost 90 days in these two data sets and in a third, previously published, data set. We develop a method to deal with short-term correlations in the data. Our results indicate that none of the data sets shows evidence for significant periodic photometric modulation
Imaging of tumour response to immunotherapy.
A wide range of cancer immunotherapy approaches has been developed including non-specific immune-stimulants such as cytokines, cancer vaccines, immune checkpoint inhibitors (ICIs), and adoptive T cell therapy. Among them, ICIs are the most commonly used and intensively studied. Since 2011, these drugs have received marketing authorisation for melanoma, lung, bladder, renal, and head and neck cancers, with remarkable and long-lasting treatment response in some patients. The novel mechanism of action of ICIs, with immune and T cell activation, leads to unusual patterns of response on imaging, with the advent of so-called pseudoprogression being more pronounced and frequently observed when compared to other anticancer therapies. Pseudoprogression, described in about 2-10% of patients treated with ICIs, corresponds to an increase of tumour burden and/or the appearance of new lesions due to infiltration by activated T cells before the disease responds to therapy. To overcome the limitation of response evaluation criteria in solid tumors (RECIST) to assess these specific changes, new imaging criteria-so-called immune-related response criteria and then immune-related RECIST (irRECIST)-were proposed. The major modification involved the inclusion of the measurements of new target lesions into disease assessments and the need for a 4-week re-assessment to confirm or not confirm progression. The RECIST working group introduced the new concept of "unconfirmed progression", into the irRECIST. This paper reviews current immunotherapeutic approaches and summarises radiologic criteria to evaluate new patterns of response to immunotherapy. Furthermore, imaging features of immunotherapy-related adverse events and available predictive biomarkers of response are presented
The shape of jamming arches in two-dimensional deposits of granular materials
We present experimental results on the shape of arches that block the outlet
of a two dimensional silo. For a range of outlet sizes, we measure some
properties of the arches such as the number of particles involved, the span,
the aspect ratio, and the angles between mutually stabilizing particles. These
measurements shed light on the role of frictional tangential forces in arching.
In addition, we find that arches tend to adopt an aspect ratio (the quotient
between height and half the span) close to one, suggesting an isotropic load.
The comparison of the experimental results with data from numerical models of
the arches formed in the bulk of a granular column reveals the similarities of
both, as well as some limitations in the few existing models.Comment: 8 pages; submitted to Physical Review
Magnetic behaviour of PrPd2B2C
We have synthesized a new quaternary borocarbide PrPdBC and
measured its magnetization, electrical resistivity and specific heat. The
compound crystallizes in the LuNiBC-type tetragonal structure
(space group {\it I4/mmm}). Above 100 K the magnetic susceptibility follows
Curie-Weiss behavior with effective moment = 3.60 , which
is very close to the value expected for Pr ions. We do not find evidence
for magnetic or superconducting transition down to 0.5 K. Specific heat
exhibits a broad Schottky type anomaly with a peak at 24 K, very likely related
to crystal electric field (CEF) excitation. The magnetic properties suggest the
presence of a singlet CEF ground state leading to a Van-Vleck paramagnetic
ground state.Comment: 2 pages, 2 figure
Penetration depth for shallow impact cratering
We present data for the penetration of a variety of spheres, dropped from
rest, into a level non-cohesive granular medium. We improve upon our earlier
work [Uehara {\it et al.} Phys. Rev. Lett. {\bf 90}, 194301 (2003)] in three
regards. First, we explore the behavior vs sphere diameter and density more
systematically, by holding one of these parameters constant while varying the
other. Second, we prepare the granular medium more reproducibly and, third, we
measure the penetration depth more accurately. The new data support our
previous conclusion that the penetration depth is proportional to the 1/2 power
of sphere density, the 2/3 power of sphere diameter, and the 1/3 power of total
drop distance
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