682 research outputs found

    Advanced Techniques for Multiparton Loop Calculations: A Minireview

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    We present an overview of techniques developed in recent years for the efficient calculation of one-loop multiparton amplitudes, in particular those relying on unitarity and collinear factorization.Comment: 5 pages, LaTeX/aipproc, presented at DIS '97, Chicago, IL, April 14-18, 199

    Efficient Blind-Spot Neural Network Architecture for Image Denoising

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    Image denoising is an essential tool in computational photography. Standard denoising techniques, which use deep neural networks at their core, require pairs of clean and noisy images for its training. If we do not possess the clean samples, we can use blind-spot neural network architectures, which estimate the pixel value based on the neighbouring pixels only. These networks thus allow training on noisy images directly, as they by-design avoid trivial solutions. Nowadays, the blind-spot is mostly achieved using shifted convolutions or serialization. We propose a novel fully convolutional network architecture that uses dilations to achieve the blind-spot property. Our network improves the performance over the prior work and achieves state-of-the-art results on established datasets

    The No-Triangle Hypothesis for N=8 Supergravity

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    We study the perturbative expansion of N=8 supergravity in four dimensions from the viewpoint of the ``no-triangle'' hypothesis, which states that one-loop graviton amplitudes in N=8 supergravity only contain scalar box integral functions. Our computations constitute a direct proof at six-points and support the no-triangle conjecture for seven-point amplitudes and beyond.Comment: 43page

    Glucose Regulation of Thrombospondin and Its Role in the Modulation of Smooth Muscle Cell Proliferation

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    Smooth muscle cells (SMC) maintained in high glucose are more responsive to IGF-I than those in normal glucose. There is significantly more thrombospondin-1 (TSP-1) in extracellular matrix surrounding SMC grown in 25 mM glucose. In this study we investigated 1) the mechanism by which glucose regulates TSP-1 levels and 2) the mechanism by which TS-1 enhances IGF-I signaling. The addition of TSP-1 to primary SMC was sufficient to enhance IGF-I responsiveness in normal glucose. Reducing TSP-1 protein levels inhibited IGF-I signaling in SMC maintained in high glucose. We determined that TSP-1 protected IAP/CD47 from cleavage and thereby facilitated its association with SHP substrate-1 (SHPS-1). We have shown previously that the hyperglycemia induced protection of IAP from cleavage is an important component of the ability of hyperglycemia to enhance IGF-I signaling. Furthermore we determined that TSP-1 also enhanced phosphorylation of the ÎČ3 subunit of the αVÎČ3 integrin, another molecular event that we have shown are critical for SMC response to IGF-I in high glucose. Our studies also revealed that the difference in the amount of TSP-1 in the two different glucose conditions was due, at least in part, to a difference in the cellular uptake and degradation of TSP-1

    Inherited Twistor-Space Structure of Gravity Loop Amplitudes

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    At tree-level, gravity amplitudes are obtainable directly from gauge theory amplitudes via the Kawai, Lewellen and Tye closed-open string relations. We explain how the unitarity method allows us to use these relations to obtain coefficients of box integrals appearing in one-loop N=8 supergravity amplitudes from the recent computation of the coefficients for N=4 super-Yang-Mills non-maximally-helicity-violating amplitudes. We argue from factorisation that these box coefficients determine the one-loop N=8 supergravity amplitudes, although this remains to be proven. We also show that twistor-space properties of the N=8 supergravity amplitudes are inherited from the corresponding properties of N=4 super-Yang-Mills theory. We give a number of examples illustrating these ideas.Comment: 32 pages, minor typos correcte

    Analytic Structure of Three-Mass Triangle Coefficients

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    ``Three-mass triangles'' are a class of integral functions appearing in one-loop gauge theory amplitudes. We discuss how the complex analytic properties and singularity structures of these amplitudes can be combined with generalised unitarity techniques to produce compact expressions for three-mass triangle coefficients. We present formulae for the N=1 contributions to the n-point NMHV amplitude.Comment: 22 pages; v3: NMHV n=point expression added. 7 point expression remove

    Reconstruction of seasonal temperature variability in the tropical Pacific Ocean from the shell of the scallop, <i>Comptopallium radula</i>

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    International audienceWe investigated the oxygen isotope composition (d18O) of shell striae from juvenile Comptopallium radula (Mollusca; Pectinidae) specimens collected live in New Caledonia. Bottom-water temperature and salinity were monitored in-situ throughout the study period. External shell striae form with a 2-day periodicity in this scallop, making it possible to estimate the date of precipitation for each calcite sample collected along a growth transect. The oxygen isotope composition of shell calcite (d18Oshell calcite) measured at almost weekly resolution on calcite accreted between August 2002 and July 2003 accurately tracks bottom-water temperatures. A new empirical paleotemperature equation for this scallop species relates temperature and d18Oshell calcite: t(°C)=20.00(+/-0.61)-3.66(+/-0.39)x(d18Oshell calcite VPDB -d18Owater VSMOW) The mean absolute accuracy of temperature estimated using this equation is 1.0 °C at temperatures between 20 and 30 °C. Uncertainties regarding the precise timing of CaCO3 deposition and the actual variations in d18Owater at our study sites probably contribute to this error. Comparison with a previously published empirical paleotemperature equation indicates that C. radula calcite is enriched in 18O by ~0.7‰ relative to equilibrium. Given the direction of this offset and the lack of correlation between shell growth rate and d18Oshell calcite, this disequilibrium is unlikely to be related to kinetic isotope effects. We suggest that this enrichment reflects (1) a relatively low pH in the scallop's marginal extrapallial fluid (EPF), (2) an isotopic signature of the EPF different from that of seawater, or (3) Rayleigh fractionation during the biocalcification process. Relative changes in d18Oshell calcite reflect seawater temperature variability at this location and we suggest that the shell of C. radula may be useful as an archive of past seawater temperatures

    Vertical structure, seasonal drawdown, and net community production in the Ross Sea, Antarctica

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    We calculate net community production (NCP) during summer 2005-2006 and spring 2006 in the Ross Sea using multiple approaches to determine the magnitude and consistency of rates. Water column carbon and nutrient inventories and surface ocean O-2/Ar data are compared to satellite-derived primary productivity (PP) estimates and C-14 uptake experiments. In spring, NCP was related to stratification proximal to upper ocean fronts. In summer, the most intense C drawdown was in shallow mixed layers affected by ice melt; depth-integrated C drawdown, however, increased with mixing depth. Delta O-2/Ar-based methods, relying on gas exchange reconstructions, underestimate NCP due to seasonal variations in surface Delta O-2/Ar and NCP rates. Mixed layer Delta O-2/Ar requires approximately 60 days to reach steady state, starting from early spring. Additionally, cold temperatures prolong the sensitivity of gas exchange reconstructions to past NCP variability. Complex vertical structure, in addition to the seasonal cycle, affects interpretations of surface-based observations, including those made from satellites. During both spring and summer, substantial fractions of NCP were below the mixed layer. Satellite-derived estimates tended to overestimate PP relative to C-14-based estimates, most severely in locations of stronger upper water column stratification. Biases notwithstanding, NCP-PP comparisons indicated that community respiration was of similar magnitude to NCP. We observed that a substantial portion of NCP remained as suspended particulate matter in the upper water column, demonstrating a lag between production and export. Resolving the dynamic physical processes that structure variance in NCP and its fate will enhance the understanding of the carbon cycling in highly productive Antarctic environments

    Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI)

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    Pulmonary hypertension (PH) is highly heterogeneous and despite treatment advances it remains a life-shortening condition. There have been significant advances in imaging technologies, but despite evidence of their potential clinical utility, practice remains variable, dependent in part on imaging availability and expertise. This statement summarizes current and emerging imaging modalities and their potential role in the diagnosis and assessment of suspected PH. It also includes a review of commonly encountered clinical and radiological scenarios, and imaging and modeling-based biomarkers. An expert panel was formed including clinicians, radiologists, imaging scientists, and computational modelers. Section editors generated a series of summary statements based on a review of the literature and professional experience and, following consensus review, a diagnostic algorithm and 55 statements were agreed. The diagnostic algorithm and summary statements emphasize the key role and added value of imaging in the diagnosis and assessment of PH and highlight areas requiring further research
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