A New Harvest: Using Solar Power to Refine Biodiesel on Native American Reservations

Sustainability is a matter of survival. The rising cost of energy and the dwindling fossil fuel resources are disproportionally affecting Indigenous communities, making them the proverbial canary in the coalmine. Native American reservations can leapfrog past fossil fuel based energy production and assert their energy sovereignty by developing renewable energy projects. Native American tribes have already been investing in renewable energy projects with the goal of becoming energy independent. The thesis proposes that tribes invest in solar powered biodiesel refining to remove their dependence on off-reservation produced energy. I use spatial analysis and GIS to demonstrate which reservations will receive the most benefit from this technology. The goal of this project is to provide tribes with a practical, real-world solution that can elevate their energy concerns and ready for implementation

Research Agenda in Intelligent Infrastructure to Enhance Disaster Management, Community Resilience and Public Safety

Modern societies can be understood as the intersection of four interdependent systems: (1) the natural environment of geography, climate and weather; (2) the built environment of cities, engineered systems, and physical infrastructure; (3) the social environment of human populations, communities and socio-economic activities; and (4) an information ecosystem that overlays the other three domains and provides the means for understanding, interacting with, and managing the relationships between the natural, built, and human environments. As the nation and its communities become more connected, networked and technologically sophisticated, new challenges and opportunities arise that demand a rethinking of current approaches to public safety and emergency management. Addressing the current and future challenges requires an equally sophisticated program of research, technology development, and strategic planning. The design and integration of intelligent infrastructure-including embedded sensors, the Internet of Things (IoT), advanced wireless information technologies, real-time data capture and analysis, and machine-learning-based decision support-holds the potential to greatly enhance public safety, emergency management, disaster recovery, and overall community resilience, while addressing new and emerging threats to public safety and security. Ultimately, the objective of this program of research and development is to save lives, reduce risk and disaster impacts, permit efficient use of material and social resources, and protect quality of life and economic stability across entire regions.Comment: A Computing Community Consortium (CCC) white paper, 4 page

Overcoming racism in the twin spheres of conservation science and practice.

It is time to acknowledge and overcome conservation's deep-seated systemic racism, which has historically marginalized Black, Indigenous and people of colour (BIPOC) communities and continues to do so. We describe how the mutually reinforcing 'twin spheres' of conservation science and conservation practice perpetuate this systemic racism. We trace how institutional structures in conservation science (e.g. degree programmes, support and advancement opportunities, course syllabuses) can systematically produce conservation graduates with partial and problematic conceptions of conservation's history and contemporary purposes. Many of these graduates go on to work in conservation practice, reproducing conservation's colonial history by contributing to programmes based on outmoded conservation models that disproportionately harm rural BIPOC communities and further restrict access and inclusion for BIPOC conservationists. We provide practical, actionable proposals for breaking vicious cycles of racism in the system of conservation we have with virtuous cycles of inclusion, equality, equity and participation in the system of conservation we want

Ambulatory function in spinal muscular atrophy: Age-related patterns of progression

Individuals with spinal muscular atrophy (SMA) type 3 are able to walk but they have weakness, gait impairments and fatigue. Our primary study objective was to examine longitudinal changes in the six-minute walk test (6MWT) and to evaluate whether age and SMA type 3 subtype are associated with decline in ambulatory function. Data from three prospective natural history studies were used. Seventy-three participants who performed the 6MWT more than once, at least 6 months apart, were included; follow-up ranged from 0.5–9 years. Only data from patients who completed the 6MWT were included. The mean age of the participants was 13.5 years (range 2.6–49.1), with 52 having disease onset before age 3 years (type 3A). At baseline, type 3A participants walked a shorter distance on average (257.1 m) than type 3B participants (390.2 m) (difference = 133.1 m, 95% confidence interval [CI] 71.8–194.3, p < 0.001). Distance walked was weakly associated with age (r = 0.25, p = 0.04). Linear mixed effects models were used to estimate the mean annual rate of change. The overall mean rate of change was -7.8 m/year (95% CI -13.6 –-2.0, p = 0.009) and this did not differ by subtype (type 3A: -8.5 m/year, type 3B: -6.6 m/year, p = 0.78), but it did differ by age group (< 6: 9.8 m/year; 6–10: -7.9 m/year; 11–19: -20.8 m/year; ≥ 20: -9.7 m/year; p = 0.005). Our results showed an overall decline on the 6MWT over time, but different trajectories were observed depending on age. Young ambulant SMA patients gain function but in adolescence, patients lose function. Future clinical trials in ambulant SMA patients should consider in their design the different trajectories of ambulatory function over time, based on age

Reflections on the 'History and Historians' of the black woman's role in the community of slaves: enslaved women and intimate partner sexual violence

Taking as points of inspiration Peter Parish’s 1989 book, Slavery: History and Historians, and Angela Davis’s seminal 1971 article, “Reflections on the black woman’s role in the community of slaves,” this probes both historiographically and methodologically some of the challenges faced by historians writing about the lives of enslaved women through a case study of intimate partner violence among enslaved people in the antebellum South. Because rape and sexual assault have been defined in the past as non-consensual sexual acts supported by surviving legal evidence (generally testimony from court trials), it is hard for historians to research rape and sexual violence under slavery (especially marital rape) as there was no legal standing for the rape of enslaved women or the rape of any woman within marriage. This article suggests enslaved women recognized that black men could both be perpetrators of sexual violence and simultaneously be victims of the system of slavery. It also argues women stoically tolerated being forced into intimate relationships, sometimes even staying with “husbands” imposed upon them after emancipation

Less Bone Loss With Maraviroc- Versus Tenofovir-Containing Antiretroviral Therapy in the AIDS Clinical Trials Group A5303 Study

Background. There is a need to prevent or minimize bone loss associated with antiretroviral treatment (ART) initiation. We compared maraviroc (MVC)- to tenofovir disoproxil fumarate (TDF)–containing ART

An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe

Histone variant H2A.Z has a conserved role in genome stability, although it remains unclear how this is mediated. Here we demonstrate that the fission yeast Swr1 ATPase inserts H2A.Z (Pht1) into chromatin and Kat5 acetyltransferase (Mst1) acetylates it. Deletion or an unacetylatable mutation of Pht1 leads to genome instability, primarily caused by chromosome entanglement and breakage at anaphase. This leads to the loss of telomere-proximal markers, though telomere protection and repeat length are unaffected by the absence of Pht1. Strikingly, the chromosome entanglement in pht1Delta anaphase cells can be rescued by forcing chromosome condensation before anaphase onset. We show that the condensin complex, required for the maintenance of anaphase chromosome condensation, prematurely dissociates from chromatin in the absence of Pht1. This and other findings suggest an important role for H2A.Z in the architecture of anaphase chromosomes

FACTORS FOR TECHNOLOGICAL APPROPRIATENESS OF RENEWABLE ENERGY OPTIONS ON NATIVE AMERICAN RESERVATIONS

133 pagesTribes are shifting to investing in renewable energy projects. Technological appropriateness is fundamental to knowing which renewable energy project is a viable investment for tribes. Because tribes have limited resources, they need to know two primary aspects of technological appropriateness: mechanical efficiency and economic efficiency. Both are based on the geography of the reservation. Using GIS, I have evaluated the mechanical and economic efficiency of solar, biodiesel and wind renewable energy systems for every reservation in the United States. In addition, I have examined in more depth the Yakama, Standing Rock Sioux, and the St. Regis Mohawk reservations to determine what mix of these technologies to create an effective renewable energy portfolio based on several factors that could affect tribes’ investment decisions. The second chapter focuses on the cultural elements that can impact a technology’s appropriateness for a reservation using linguistic analysis and GIS to demonstrate the relationship between culture, technology and the land. The third chapter examines opportunities for tribes to create stronger collaborations with policy makers and academics by using linguistic analysis to highlight the highest frequency of words that each group uses in their documents concerning energy. The fourth chapter analyses the resource availability for each technology for each reservation using GIS to determine the environmental and economic factors that can impact a technology’s appropriateness. The fifth chapter highlights the best practices that researchers can use when collaborating with Indigenous communities to conduct research as a means to strengthen those collaborations to increase the likelihood that a renewable energy project on a reservation will be successful. The goal of this research is to provide tribes with a tool that will help them to partner with government and academic institutions to build renewable energy systems to strengthen the tribe’s sovereignt