Beyond the Stern Review: Lessons from a risky venture at the limits of the cost–benefit analysis

International audienceThis paper argues that debates amongst economists triggered by the Stern Review are partly relevant, focusing on key parameters translating real ethical issues, and partly misplaced in that they do not consider enough other determinants of climate change damages: i) the specifications of the utility function used for the assessments (preference for the environment, preference for smooth growth paths), ii) the interplay between uncertainty and the sequentiality of the decision, and iii) whether the growth engines behind the integrated assessment models can account for transient disequilibrium and sub-optimality. We derive some suggestions for any future research agenda in integrated assessment modelling, whatever the position of the analysts about the relevance of the intertemporal optimisation framework and the Bayesian approach to uncertainty in the climate affair

Electrical and optical measurements of the bandgap energy of a light-emitting diode

International audienceSemiconductors materials are at the basis of electronics. Most electronic devices are made of semiconductors. The operation of these components is well described by quantum physics which is a little mysterious to students. One of the intrinsic parameters of semiconductors is their bandgap energy Eg. In the case of light-emitting diodes (LEDs) Eg fixes the colour of the light emitted by the diodes. We propose in this article a lab work allowing a comparison of Eg of a green LED obtained by both electrical and optical measurements. The two slightly different results can be explained by the theoritical knowledges of the students on solid physics and electronic devices internal architecture

Some Reflections about the Ancient Aqueduct of Galermi (Syracuse, Italy)

Since 2012, the Centre Camille Jullian team carries out an interdisciplinary study of the aqueduct Galermi, architectural work and hydraulic engineering of about 30 km long. This aqueduct, built between the 5th century BC and the Roman Empire, first supplied drinking water to Greek and/or Roman Syracuse. In the 16th–17th centuries, partial transformations have been done and changed the function of the channel, with the installation of flour mills. In the 19th century, the new Italian state gradually expropriated immediate neighbors who exploited abusively the aqueduct. It was then devoted only to irrigate the Syracusan territory according to a system of concessions that has almost remained unchanged since the 19th century. The paper will present this program and the last results that the team obtained in the last two years, particularly about intakes of water and underground galleries, and which chronology can be proposed

Optimal control models and elicitation of attitudes towards climate damages

This paper examines the consequences of various attitudes towards climate damages through a family of stochastic optimal control models (RESPONSE): cost-efficiency for a given temperature ceiling; cost-benefit analysis with a "pure preference for current climate regime" and full cost-benefit analysis. The choice of a given proxy of climate change risks is actually more than a technical option. It is essentially motivated by the degree of distrust regarding the legitimacy of an assessment of climate damages and the possibility of providing in due time reliable and non controversial estimates. Our results demonstrate that a) for early decades abatement, the difference between various decision-making frameworks appears to matter less than the difference between stochastic and non stochastic approach given the cascade of uncertainty from emissions to damages; b) in a stochastic approach, the possibility of non-catastrophic singularities in the damage function is sufficient to significantly increase earlier optimal abatements; c) a window of opportunity for action exists up to 2040: abatements further delayed may induce significant regret in case of bad news about climate response or singularities in damages.Cost-efficiency; Cost-benefit; Climate sensitivity; Climate change damages; Uncertainty; Optimal climate policy; Decision making frameworks

An introduction to photocatalysis through methylene blue photodegradation

International audienceWe described a simple experimental setup for a lab work on the photocatalytic degradation of methylene blue by T iO 2 nanoparticles. The photocatalysis process can be used for many applications. Treatments for diluted wastewaters industries, air purifying in underground car parks, preventing fouling on glass surfaces, these are some of the things this phenomenon has the ability to do. The described experiment is easy to perform and the interpretation can be easily adapted to different level of students: from high school students demonstrating their interests on a sustainable development, to students who are getting Masters in the science department that want to propose a full explanation of all the phenomenon of the photocatalytic process. Starting by a description of the experimental setup , we analysed the photocatalyst nanoparticles and applied the Langmuir-Hinshelwood model to our experimental data. Finally we discussed shortly on the respective energetic levels of the photocatalyst semiconductor and the methylene blue

Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell

The kissing-loop complex that initiates dimerization of genomic RNA is crucial for Human Immunodeficiency Virus Type 1 (HIV-1) replication. We showed that owing to its strong similitude with the bacterial ribosomal A site it can be targeted by aminoglycosides. Here, we present its crystal structure in complex with neamine, ribostamycin, neomycin and lividomycin. These structures explain the specificity for 4,5-disubstituted 2-deoxystreptamine (DOS) derivatives and for subtype A and subtype F kissing-loop complexes, and provide a strong basis for rational drug design. As a consequence of the different topologies of the kissing-loop complex and the A site, these aminoglycosides establish more contacts with HIV-1 RNA than with 16S RNA. Together with biochemical experiments, they showed that while rings I, II and III confer binding specificity, rings IV and V are important for affinity. Binding of neomycin, paromomycin and lividomycin strongly stabilized the kissing-loop complex by bridging the two HIV-1 RNA molecules. Furthermore, in situ footprinting showed that the dimerization initiation site (DIS) of HIV-1 genomic RNA could be targeted by these aminoglycosides in infected cells and virions, demonstrating its accessibility

Note sur la sensibilité héréditaire des bovins à la streptothricose

cf. fichier PDF de l'article