William Duer to John Matthews, April 29, 1782

William Duer wrote from the Office of Finance to John Matthews, Governor of South Carolina. He wrote acknowledging a letter received at Jacksonburgh and said he was happy the Governor would be sending Accounts of Expenditures for January, February, and March. Once those reports were received and he spoke with Mr. Hall, William would have been able to judge a system the state had adopted.https://digitalcommons.kean.edu/lhc_1780s/1078/thumbnail.jp

Articles of Agreement between William Duer and William Bingham

Articles of Agreement between William Duer and William Bingham for the purchase of two million acreshttps://digitalmaine.com/bingham_purchase/1000/thumbnail.jp

No. 3, Office of Finance, between 1782-1783

The top of the document is labeled No. 3. It includes copies of four letters written from the Office of Finance about the cost of the American Revolution. It likely belonged to John Kean. Details about the copies: George Abbot Hall, Receiver for South Carolina, June 10, 1782, no signature. September 11, 1782, no signature. January 22, 1783, signed by R. [Robert] Morris. May 16, 1783, signed by Wm [William] Duer, Secretary.https://digitalcommons.kean.edu/lhc_1780s/1015/thumbnail.jp

The curious case of (caffeine).(benzoic acid): how heteronuclear seeding allowed the formation of an elusive cocrystal

Cocrystals are modular multicomponent solids with exceptional utility in synthetic chemistry and materials science. A variety of methods exist for the preparation of cocrystals yet, some promising cocrystal phases have proven to be intractable synthetic targets. We describe a strategy for the synthesis of the pharmaceutically relevant (caffeine).(benzoic acid) cocrystal (1), which persistently failed to form using a broad range of established techniques. State-of-the-art crystal structure prediction methods were employed to assess the possible existence of a thermodynamically stable form of 1, and to identify appropriate heteronuclear seeds for corystallization. Once introduced, the designed heteronuclear seeds facilitated the formation of 1 and, significantly, continued to act as long-lasting laboratory .contaminants., which encouraged cocrystal formation even when present at such low levels as to evade detection. The seeding technique described thus enables the synthesis of cocrystals regarded as unobtainable under desired conditions, and potentially signifies a new direction in the field of materials research

Centralized, Stepped, Patient Preference–Based Treatment for Patients With Post–Acute Coronary Syndrome Depression

IMPORTANCE: Controversy remains about whether depression can be successfully managed after acute coronary syndrome (ACS) and the costs and benefits of doing so. OBJECTIVE: To determine the effects of providing post-ACS depression care on depressive symptoms and health care costs. DESIGN: Multicenter randomized controlled trial. SETTING: Patients were recruited from 2 private and 5 academic ambulatory centers across the United States. PARTICIPANTS: A total of 150 patients with elevated depressive symptoms (Beck Depression Inventory [BDI] score ≥10) 2 to 6 months after an ACS, recruited between March 18, 2010, and January 9, 2012. INTERVENTIONS: Patients were randomized to 6 months of centralized depression care (patient preference for problem-solving treatment given via telephone or the Internet, pharmacotherapy, both, or neither), stepped every 6 to 8 weeks (active treatment group; n = 73), or to locally determined depression care after physician notification about the patient's depressive symptoms (usual care group; n = 77). MAIN OUTCOME MEASURES: Change in depressive symptoms during 6 months and total health care costs. RESULTS: Depressive symptoms decreased significantly more in the active treatment group than in the usual care group (differential change between groups, -3.5 BDI points; 95% CI, -6.1 to -0.7; P = .01). Although mental health care estimated costs were higher for active treatment than for usual care, overall health care estimated costs were not significantly different (difference adjusting for confounding, -$325; 95$2639 to $1989; P = .78). CONCLUSIONS: For patients with post-ACS depression, active treatment had a substantial beneficial effect on depressive symptoms. This kind of depression care is feasible, effective, and may be cost-neutral within 6 months; therefore, it should be tested in a large phase 3 pragmatic trial. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT01032018

Design and baseline data from the vanguard of the Comparison of Depression Interventions after Acute Coronary Syndrome (CODIACS) randomized controlled trial

This paper describes the rationale and design of the vanguard for the Comparison of Depression Interventions after Acute Coronary Syndrome (CODIACS), a multicenter, randomized, controlled trial of a patient preference‐based, stepped care protocol for persistent depressive symptoms after acute coronary syndrome (ACS). The overall aim of the vanguard phase was to determine whether the patient-preference, stepped care protocol, which is based on the intervention used in the recent Coronary Psychosocial Evaluation Studies (COPES) trial, was feasible in patients with recent ACS who were recruited from 5 geographically diverse sites. Innovative design features of this trial include randomization to either initial patient-preference of treatment or to a referred care arm in which the primary care provider decided upon care. Additionally, delivery of psychotherapy was accomplished by telephone, or webcam, depending upon patient preference. The vanguard phase provides estimates of eligibility and screening/enrollment ratios, patient acceptance of screening, and retention. In this report, we describe the innovative features and the baseline results of the vanguard phase of CODIACS. The data from this vanguard study will be used to finalize planning for a large, phase III clinical trial designed to evaluate the effect of treatment on depressive symptoms, coronary events, and death

Enthalpy of solvation correlations for organic solutes and gases dissolved in 1-propanol and tetrahydrofuran

This article discusses the enthalpy of solvation correlations for organic solutes and gases dissolved in 1-propanol and tetrahydrofuran

A comparative study of three measures of achievement motivation

The primary purpose of this research was to determine if an instrument could be developed which would better discriminate between ninth-grade boys who perform a complex task with high achievement motivation and those who perform a complex task with low achievement motivation than would the TAT n Ach measure or the Mehrabian Scales of Achievement Motivation. Literature relating to previous developmental research on the theory of achievement motivation was reviewed and discussed in summary. The study had two objectives. The first was construction of an instrument, the Duer Test of Achievement Motivation (DTAM). In constructing the DTAM, the following steps were taken: (1) a format was chosen for the DTAM, somewhat similar to Osgood's semantic differential technique; (2) adjectives were selected through factor analysis; (3) pictures were created to serve as 'concepts' to be rated by subjects; (4) factor analysis was utilized to obtain the structure of the instrument, with three dimensions emerging and; (5) the DTAM was administered to 28 ninth-grade boys and related to two risk taking exercises. The derived instrument was found to have moderate validity when used to discriminate between high and low need achievers. The second objective of the study was to determine the predictive validity of the DTAM, TAT n Ach measure, and Mehrabian scales when used to discriminate between high and low achievers engaged in a risk taking experiment. The DTAM was found to be superior to the other two instruments in discriminating between those classified as high in achievement motivation and those classified as low in achievement motivation. Of special importance were findings concerning use of risk taking experiments as criteria for achievement motivation research. [...]Education, College o

A letter addressed to Cadwallader D. Colden, esquire. In answer to the strictures, contained in his "Life of Robert Fulton," upon the report of the select committee,

Mode of access: Internet

A course of lectures on the constitutional jurisprudence of the United States : delivered annually in Columbia College, New York /

Mode of access: Internet