1,006 research outputs found

    Multiple shaking tables tests of seismic pounding effect of reinforced concrete bridge model

    Get PDF
    In order to investigate the longitudinal pounding effect of highway bridges with high-piers under strong ground motions, multiple shaking tables tests of a 1/10 scaled continuous rigid frame and simply-supported girder bridge with high-piers were carried out. The pounding responses of the bridge model under different earthquake excitations including the uniform excitation and the traveling wave excitation were studied, and the effectiveness of the dampers and isolation bearings for reducing the seismic pounding effect were analyzed and discussed. Test results indicate that the traveling wave effect is the important factor in seismic pounding response of high pier bridges. Additional dampers can mitigate the pounding effect apparently and play a role in reducing seismic response for bridge superstructures. Compared with conventional rubber bearing (RB), the decreases in the relative displacement and the pounding force between adjacent girders were 30 % and 55 % with lead rubber bearing (LRB) in this experiment, respectively. Seismic pounding effect of bridge superstructures depends on different structural dynamic properties of adjacent girders and characteristics of ground motions

    Hysteresis behavior of reinforced concrete bridge piers considering strength and stiffness degradation and pinching effect

    Get PDF
    In order to effectively simulate the nonlinear hysteresis behavior of reinforced concrete (RC) bridge piers under strong earthquake excitation, an improved nonlinear hysteresis model for RC bridge piers was developed and its controlling parameters were determined considering stiffness and strength degradation and pinching effect based on classical Bouc-Wen model. The improved model can be carried out to predict the nonlinear hysteresis behavior of RC bridge piers under various failure modes using MATLAB/ Simulink program. Cyclic tests of different failure mode bridge column specimens were performed under constant axial load with lateral bending. The results did show that force-displacement relationship curves of bridge column specimens derived from theoretical analysis agree well with experimental results. The nonlinear hysteresis behavior of bridge column specimen was simulated under 2008 Wenchuan earthquake excitation and its failure modes were identical with real earthquake damage of bridge column. The improved analytical models in the paper were applied to accurately predicting the nonlinear hysteresis behavior of RC bridge columns with strength and stiffness degradations and the pinching effect subjected to strong earthquake motion

    Network‐based feature selection reveals substructures of gene modules responding to salt stress in rice

    Get PDF
    Rice, an important food resource, is highly sensitive to salt stress, which is directly related to food security. Although many studies have identified physiological mechanisms that confer tolerance to the osmotic effects of salinity, the link between rice genotype and salt tolerance is not very clear yet. Association of gene co‐expression network and rice phenotypic data under stress has penitential to identify stress‐responsive genes, but there is no standard method to associate stress phenotype with gene co‐expression network. A novel method for integration of gene co‐expression network and stress phenotype data was developed to conduct a system analysis to link genotype to phenotype. We applied a LASSO‐based method to the gene co‐expression network of rice with salt stress to discover key genes and their interactions for salt tolerance‐related phenotypes. Submodules in gene modules identified from the co‐expression network were selected by the LASSO regression, which establishes a linear relationship between gene expression profiles and physiological responses, that is, sodium/potassium condenses under salt stress. Genes in these submodules have functions related to ion transport, osmotic adjustment, and oxidative tolerance. We argued that these genes in submodules are biologically meaningful and useful for studies on rice salt tolerance. This method can be applied to other studies to efficiently and reliably integrate co‐expression network and phenotypic data

    SEMv2: Table Separation Line Detection Based on Instance Segmentation

    Full text link
    Table structure recognition is an indispensable element for enabling machines to comprehend tables. Its primary purpose is to identify the internal structure of a table. Nevertheless, due to the complexity and diversity of their structure and style, it is highly challenging to parse the tabular data into a structured format that machines can comprehend. In this work, we adhere to the principle of the split-and-merge based methods and propose an accurate table structure recognizer, termed SEMv2 (SEM: Split, Embed and Merge). Unlike the previous works in the ``split'' stage, we aim to address the table separation line instance-level discrimination problem and introduce a table separation line detection strategy based on conditional convolution. Specifically, we design the ``split'' in a top-down manner that detects the table separation line instance first and then dynamically predicts the table separation line mask for each instance. The final table separation line shape can be accurately obtained by processing the table separation line mask in a row-wise/column-wise manner. To comprehensively evaluate the SEMv2, we also present a more challenging dataset for table structure recognition, dubbed iFLYTAB, which encompasses multiple style tables in various scenarios such as photos, scanned documents, etc. Extensive experiments on publicly available datasets (e.g. SciTSR, PubTabNet and iFLYTAB) demonstrate the efficacy of our proposed approach. The code and iFLYTAB dataset are available at https://github.com/ZZR8066/SEMv2

    Genes and pathways correlated with heat stress responses and heat tolerance in maize kernels

    Get PDF
    Global warming leads to frequent extreme weather, especially the extreme heat events, which threating the safety of maize production. Here we selected a pair of maize inbred lines, PF5411-1 and LH150, with significant differences in heat tolerance at kernel development stage. The two maize inbred lines were treated with heat stress at kernel development stage. Compared with the control groups, transcriptomic analysis identified 770 common up- and down-regulated genes between PF5411-1 and LH150 under heat stress conditions, and 41 putative TFs were predicted. Based on the interaction term of the two-factorial design, we also identified 6,744 differentially regulated genes between LH150 and PF5411-1, 111 common up-regulated and 141 common down-regulated genes were overlapped with the differentially regulated genes, respectively. Combined with proteins and metabolites data, several key pathways including seven differentially regulated genes were highly correlated with the heat tolerance of maize kernels. The first is the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway ko04141: protein processing in endoplasmic reticulum, four small heat shock protein (sHSP) genes were enriched in this pathway, participating with the process of ER-associated degradation (ERAD). The second one is the myricetin biosynthesis pathway, a differentially regulated protein, flavonoid 3’,5’-hydroxylase [EC:1.14.14.81], catalyzed the synthesis of myricetin. The third one is the raffinose metabolic pathway, one differentially regulated gene encoded the raffinose synthase controlled the synthesis of raffinose, high level of raffinose enhances the heat tolerance of maize kernels. And the last one is the ethylene signaling pathway. Taken together, our work identifies many genes responded to heat stress in maize kernels, and finds out seven genes and four pathways highly correlated with heat tolerance of maize kernels

    Hysteresis behavior of reinforced concrete bridge piers considering strength and stiffness degradation and pinching effect

    Get PDF
    In order to effectively simulate the nonlinear hysteresis behavior of reinforced concrete (RC) bridge piers under strong earthquake excitation, an improved nonlinear hysteresis model for RC bridge piers was developed and its controlling parameters were determined considering stiffness and strength degradation and pinching effect based on classical Bouc-Wen model. The improved model can be carried out to predict the nonlinear hysteresis behavior of RC bridge piers under various failure modes using MATLAB/ Simulink program. Cyclic tests of different failure mode bridge column specimens were performed under constant axial load with lateral bending. The results did show that force-displacement relationship curves of bridge column specimens derived from theoretical analysis agree well with experimental results. The nonlinear hysteresis behavior of bridge column specimen was simulated under 2008 Wenchuan earthquake excitation and its failure modes were identical with real earthquake damage of bridge column. The improved analytical models in the paper were applied to accurately predicting the nonlinear hysteresis behavior of RC bridge columns with strength and stiffness degradations and the pinching effect subjected to strong earthquake motion

    Hysteresis behavior of reinforced concrete bridge piers considering strength and stiffness degradation and pinching effect

    Get PDF
    In order to effectively simulate the nonlinear hysteresis behavior of reinforced concrete (RC) bridge piers under strong earthquake excitation, an improved nonlinear hysteresis model for RC bridge piers was developed and its controlling parameters were determined considering stiffness and strength degradation and pinching effect based on classical Bouc-Wen model. The improved model can be carried out to predict the nonlinear hysteresis behavior of RC bridge piers under various failure modes using MATLAB/ Simulink program. Cyclic tests of different failure mode bridge column specimens were performed under constant axial load with lateral bending. The results did show that force-displacement relationship curves of bridge column specimens derived from theoretical analysis agree well with experimental results. The nonlinear hysteresis behavior of bridge column specimen was simulated under 2008 Wenchuan earthquake excitation and its failure modes were identical with real earthquake damage of bridge column. The improved analytical models in the paper were applied to accurately predicting the nonlinear hysteresis behavior of RC bridge columns with strength and stiffness degradations and the pinching effect subjected to strong earthquake motion

    Stability and drug dissolution evaluation of Qingkailing soft/hard capsules based on multi-component quantification and fingerprint pattern statistical analysis

    Get PDF
    Purpose: To carry out a post-marketing evaluation of the stability and drug dissolution of Qingkailing soft/hard capsules.Methods: High performance liquid chromatography with diode array detection (HPLC-DAD) method was developed for the determination of three key ingredients (chlorogenic acid, geniposide and baicalin) and fingerprints of QKL soft/hard capsules. Stability tests were carried out based on long-term testing. The drug release profile of Qingkailing soft and hard capsules were studied using semi-bionic incubation experiments.Results: The linearity, precision, stability, repeatability and recovery of HPLC and fingerprint all met the requirements of CFDA. Stability data from long-term studies showed that within 6 months the contents of the three key ingredients in both soft and hard capsules remained > 90 %. However, fingerprint pattern statistical analysis showed that the soft capsule is more stable than the hard capsule. Furthermore, the key ingredients of the hard capsule dissolved much faster (p < 0.05) than from the soft capsule. The level of dissolved drug of hard capsule is about 4 times the rate of soft capsule, after a 4-h incubation in gastric lavage fluid. In intestinal lavage fluid, more than 90 % of chlorogenic acid, geniposide and baicalin of hard capsule were dissolved in 2 h, while the soft capsule displayed a 12 h sustained release. Fingerprint pattern statistical analysis also showed that most of the components of soft capsule dissolved after 8 h.Conclusion: Compared with the hard capsule, Qingkailing soft capsule has certain advantages in stability and drug dissolution, which may affect the biopharmaceutics and the clinical effects of the drug.Keywords: Qingkailing capsule, Chlorogenic acid, Geniposide, Baicalin, Fingerprint, Sustained release, Principal component analysi

    The rise of urbanism and exchange network: reconstruction of a 4000-year local history of Xinjiang, northwestern China

    Get PDF
    Urbanization is one of the milestones in the development of human society. Many regions in the southern parts of ‘the old world’ demonstrating an early emergence of agriculture also witnessed the flourishing of some of the earliest cities. Recent, yet still sparse, archaeological evidence appears to indicate a relatively later time for early urbanism in central Eurasia. However, given its vital geographic location and cultural nexus between East and West, more attention should be paid to the sedentary communities and their cities in oases amid the vast droughty desert, particularly in light of the rapidly increasing number of publications on early pastoralism and related communication routes along mountain chains and rivers. This study reveals the trajectory of urbanization and its role in the establishment of an exchange network in Xinjiang’s oasis region via reconstruction of the chronological sequence of the local societal history of the Baiyang River Basin along the southern piedmont of the Eastern Tianshan Mountains. A thorough archaeological investigation and refined radiocarbon dating programme was carried out and coupled with information from historical documentation within a Bayesian statistical framework. The results indicate three pulses of local urbanization during: the Early Iron Age, Tang–Yuan period, and Qing Dynasty, respectively. Combining this with evidence from other parts of Xinjiang, we re-evaluate the role of oasis urbanism in the promotion of trans-regional exchange
    • 

    corecore