504 research outputs found

    Stocktaking methods of facilities in a state of ruin

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    The stocktaking is the basic form of presenting and protecting the object of the historic ruin. It also allows to monitor the behavior state and the degradation progress of an object. Objects in ruin are very specifi c because they usually do not have elements typical for an existing building. This means that in the case of ruins, methods of stocktaking taken in the same way as in the case of traditional facilities will be insuffi cient. Elements of objects in ruin often have complicated and diverse geometry, diffi cult and not completely secure access to all elements. The article presents methods that can be helpful in the stocktaking of such objects. Each method describes the necessary equipment and instruments, the method of taking measurements, accuracy, advantages, and limitations. The paper also presents examples of application for selected methods

    Assessment of Hazard Due to Release of Gaseous Ammonia from the Fly Ash-Water Mixture Applied in Longwall Mine Gobs

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    ABSTRACTPurposeThe introduction of flue gas denitrification technologies by selective catalytic reduction (SCR) or selective non-catalytic reduction (SNCR) in coal fired plants resulted in an increase of ammonia content in fly ash. The utilization of fly ash in fire and ventilation prevention of hard coal mines causes the release of ammonia from a fly ash-water mixture. In the applied technology of the ash and water mixture, ammonia in gaseous form is discharged and mixes with the air flowing through the mine airways. In this article, reference is made to the risk assessment of gaseous ammonia in the longwall area during the application of the fly ash-water mixture to the gobs in the U-tube ventilation system.MethodsThe test methods include: ammonia release from ash and water mixtures at various temperatures and in respect to different proportions of water to ash with use of a multigas analyzer with an FTIR detector.ResultsThe results of the laboratory tests helped to determine the size of the ammonia stream released from the fly ash-water mixture in respect to different ratios of water to ash.Practical implicationsLaboratory studies allow for ventilation and gaseous analysis to assess the level of ammonia risk, in the mine airways, from exhaust air discharged from the longwall area.Originality/valueBased on the literature review, this type of research has not been carried out so far

    A Spectroscopic and Photometric Investigation of the Mercury-Manganese Star KIC 6128830

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    The advent of space-based photometry provides the opportunity for the first precise characterizations of variability in Mercury-Manganese (HgMn/CP3) stars, which might advance our understanding of their internal structure. We have carried out a spectroscopic and photometric investigation of the candidate CP3 star KIC 6128830. A detailed abundance analysis based on newly-acquired high-resolution spectra was performed, which confirms that the star's abundance pattern is fully consistent with its proposed classification. Photometric variability was investigated using four years of archival Kepler data. In agreement with results from the literature, we have identified a single significant and independent frequency f1f_1=0.2065424 d1^{-1} with a peak-to-peak amplitude of \sim3.4 mmag and harmonic frequencies up to 5f15f_1. Drawing on the predictions of state-of-the-art pulsation models and information on evolutionary status, we discuss the origin of the observed light changes. Our calculations predict the occurrence of g-mode pulsations at the observed variability frequency. On the other hand, the strictly mono-periodic nature of the variability strongly suggests a rotational origin. While we prefer the rotational explanation, the present data leave some uncertainty.Comment: 13 pages, 13 figures, accepted for publication in MNRA

    Regulace leukocytární signalizace adaptorovými proteiny se speciálním zaměřením na Csk vazebné proteiny

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    Signaling through leukocyte receptors is an integral part of immune system homeostasis and it is crucial for immune response. Signal initiation and propagation has to be properly spatiotemporally controlled not to trigger pathological immune activation. Important part in the initiation and regulation of signaling is played by adaptor proteins. These adaptors can be involved in positive or negative control, or both, depending on what effector enzymes they bind. In presented work we studied the involvement of two adaptor proteins PSTPIP2 and LST1/A in leukocyte signaling. Both adaptors interact with several inhibitory enzymes which implicates these proteins in negative regulation of signaling. We extended current understanding of why the deficiency in the expression of one of these adaptors, PSTPIP2, results in the initiation and progression of autoinflammatory disorder chronic multifocal osteomyelitis disease in mice by describing its interactions with Csk kinase and SHIP1 phosphatase. In particular we have shown that PSTPIP2 deficiency leads to increased activity of signaling pathways and increased processing of IL-1β in neutrophils in response to a variety of stimuli and that binding to SHIP1 contributes to PSTPIP2-mediated suppression of inflammation. Our biochemical analysis of the second of...Signalizace přes receptory leukocytů je nedílnou součástí homeostáze imunitního systému a naprosto kritická pro imunitní odpověď. Iniciace signálu a jeho šíření musí být správně kontrolováno aby se aktivace imunitního systému nezvrhla v patologickou. Důležitou úlohu v zahájení signalizace a její regulaci hrají adaptorové proteiny. Tyto adaptory se podílejí na pozitivní nebo negativní kontrole, případně mají duální funkci. Jejich funkce je určena aktivitou enzymů, které na sebe váží. V předkládané práci jsme se zabývali dvěma adaptorovými proteiny, PSTPIP2 a LST1/A, a jejich funkcí v signalizaci leukocytů. Oba adaptory na sebe váží několik enzymů s inhibiční funkcí což poukazuje na jejich úlohu v negativní regulaci signalizace. Rozšířili jsme současné znalosti o vzniku a vývoji zánětlivého onemocnění označovaného jako chronická multifokální osteomyelitida, které se rozvíjí u myší v důsledku deficience v expresi adaptoru PSTPIP2, tím, že jsme popsali interakce tohoto adaptoru s kinázou Csk a fosfatázou SHIP1. Konkrétně jsme ukázali, že absence PSTPIP2 vede ke zvýšené aktivitě signálních drah a zvýšenému štěpení IL-1β v neutrofilech v odpovědi na celou řadu stimulací, a že vazba SHIP1 přispívá k potlačování zánětu zprostředkovanému adaptorem PSTPIP2. Biochemická analýza druhého adaptorového proteinu,...Department of Cell BiologyKatedra buněčné biologieFaculty of SciencePřírodovědecká fakult

    The Influence of Anchoring-Group Structure on the Lubricating Properties of Brush-Forming Graft Copolymers in an Aqueous Medium

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    We have compared the lubricating properties of two different PEG-grafted, polycationic, brush-forming copolymers to gain a deeper understanding of the role of the polyionic backbone in the lubricating behavior of such materials, when used as additives in aqueous lubricant systems. Previously, poly(l-lysine)-graft-poly(ethylene glycol) (PLL-g-PEG) has been shown to adsorb onto oxide surfaces from aqueous solution and substantially lower frictional forces. Poly(allylamine)-graft-poly(ethylene glycol) (PAAm-g-PEG), which also has a polycationic backbone, has been synthesized in several different architectures, and its performance investigated via adsorption tests, rolling- and sliding-contact tribometry, and the surface forces apparatus. These tests show a clear reduction of friction forces with PAAm-g-PEG compared to water alone. However, when compared with PLL-g-PEG, while PAAm-g-PEG copolymers did not adsorb to the same extent or exhibit as high a lubricity in sliding geometry, they showed a similar lubricating effect under rolling conditions. The difference in the chemical structure of the backbones, especially the flexibility of the anchoring groups, appears to significantly influence both the extent and kinetics of polymer adsorption, which in turn influences lubrication behavio

    Usage of the VORNE 800XL production monitoring and indicator visualization system for the development of the project "Effect in a minute“

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    Nowadays, in most of the manufacturing factories, entrepreneurs tries to “slim down” their processes. To achieve that they attempts to implement some of the “Lean Manufacturing” methodology’s methods and tools with better or worst effects. Most of the failures results from the wrong approach to that subject. Leaders wants their teams to do anything faster and cheaper but too often their teammates does not exactly know why they have to do something as they do not see the goal of them. The easiest way to improve the understanding of implementation of “Lean Manufacturing” is to train whole team and arrange workshops that can educate everyone and lead the team to the common objective. One of the ideas of such an activity is the project called “Effect in a minute” created by the students from the student research group called “Management” from University of Science and Technology from Cracow (AGH- Kraków). In this article, there will be described the practical aspect of such an activity and prospect of the project’s development based on the usage of production monitoring and indicator visualization system called VORNE 800XL
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