4,754 research outputs found
Opposite Effects of Central Amygdaloid Vasopressin and Oxytocin on the Regulation of Conditioned Stress Responses in Male Rats
Range Queries on Uncertain Data
Given a set of uncertain points on the real line, each represented by
its one-dimensional probability density function, we consider the problem of
building data structures on to answer range queries of the following three
types for any query interval : (1) top- query: find the point in that
lies in with the highest probability, (2) top- query: given any integer
as part of the query, return the points in that lie in
with the highest probabilities, and (3) threshold query: given any threshold
as part of the query, return all points of that lie in with
probabilities at least . We present data structures for these range
queries with linear or nearly linear space and efficient query time.Comment: 26 pages. A preliminary version of this paper appeared in ISAAC 2014.
In this full version, we also present solutions to the most general case of
the problem (i.e., the histogram bounded case), which were left as open
problems in the preliminary versio
Blood volume changes
Analysis of radionuclide volume determinations made for the crewmembers of selected Gemini and Apollo missions showed that orbital spaceflight has an effect on red cell mass. Because the methods and the protocol developed for earlier flights were used for the crews of the three Skylab missions, direct comparisons are possible. After each Skylab mission, decreases were found in crewmembers' red cell masses. The mean red cell mass decrease of 11 percent or 232 milliliters was approximately equal to the 10 percent mean red cell mass decrease of the Apollo 14 to 17 crewmembers. The red cell mass drop was greatest and the postrecovery reticulocyte response least for crewmembers of the 28-day Skylab 2 mission. Analyses of data from the red cell mass determinations indicate that the red cell mass drops occurred in the first 30 days of flight and that a gradual recovery of the red cell mass deficits began approximately 60 days after launch. The beginning of red cell mass regeneration during the Skylab 4 flight may explain the higher postmission reticulocyte counts
Strong Pinning Enhancement in MgB2 Using Very Small Dy2O3 Additions
0.5 to 5.0 wt.% Dy2O3 was in-situ reacted with Mg + B to form pinned MgB2.
While Tc remained largely unchanged, Jc was strongly enhanced. The best sample
(only 0.5 wt.% Dy2O3) had a Jc of 6.5 x 10^5 A/cm^2 at 6K, 1T and 3.5 x 10^5
A/cm^2 at 20K, 1T, around a factor of 4 higher compared to the pure sample, and
equivalent to hot-pressed or nano-Si added MgB2 at below 1T. Even distributions
of nano-scale precipitates of DyB4 and MgO were observed within the grains. The
room temperature resistivity decreased with Dy2O3 indicative of improved grain
connectivity.Comment: 13 pages, 4 figures and 1 tabl
Vasopressinergic modulation of stress responses in the central amygdala of the Roman high-avoidance and low-avoidance rat
The central nucleus of the amygdala (CEA) is selectively involved in the passive component of the behavioral (immobility) and the accompanying parasympathetic response during conditioned, stressful environmental challenges. Vasopressinergic mechanisms in the brain seem to play a role in these stress responses. The effects of the neuropeptides arginine-8-vasopressin (AVP) and oxytocin (OXT) on modulating CEA activity during conditioned stress of inescapable footshock were studied in male Roman high-avoidance (RHA/Verh) and low-avoidance (RLA/Verh) rats, psychogenetically selected on the basis of shuttle-box acquisition behavior. In RLA/Verh rats, the cardiac and behavioral responses to the conditioned emotional stressor were bradycardia and immobility, suggesting an important role for the CEA in these rats. The RHA/Verh rats, however, failed to show any change in heart rate or immobility in response to a conditioned stress situation. The low dose of AVP (20 pg) in the CEA of conscious RLA/Verh rats caused an enhancement of the stress-induced bradycardiac and immobility response. However, the high dose of AVP (2 ng) and OXT (200 pg) attenuated the bradycardiac and immobility responses in the RLA/Verh rats. Infusion of AVP and OXT in the RHA/Verh rats failed to induce any change in heart rate nr immobility. Binding studies revealed that the AVP receptor selectively binds AVP with high affinity. In contrast, the OXT receptor recognizes both AVP and OXT with a similar (but lower) affinity. This suggests that the behavioral and autonomic responses of the high dose of AVP may be caused by OXT receptor stimulation. In conclusion, on the basis of the present results one may hypothesize that CEA differences in AVP and OXT innervation and/or receptor densities may contribute to the differences in coping strategy found in these animals.
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Languages and Learning at Key Stage 2: A Longitudinal Study Final Report
In 2006, The Open University, the University of Southampton and Canterbury Christ Church University were commissioned by the then Department for Education and Skills (DfES), now Department for Children, Schools and Families (DCSF) to conduct a three-year longitudinal study of languages learning at Key Stage 2 (KS2). The qualitative study was designed to explore provision, practice and developments over three school years between 2006/07 and 2008/09 in a sample of primary schools and explore children’s achievement in oracy and literacy, as well as the possible broader cross-curricular impact of languages learning
Improved Current Densities in MgB2 By Liquid-Assisted Sintering
Polycrystalline MgB2 samples with GaN additions were prepared by reaction of
Mg, B, and GaN powders. The presence of Ga leads to a low melting eutectic
phase which allowed liquid phase sintering and produces plate-like grains. For
low-level GaN additions (5% at. % or less), the critical transition
temperature, Tc, remained unchanged and in 1T magnetic field, the critical
current density, Jc was enhanced by a factor of 2 and 10, for temperatures of
\~5K and 20K, respectively. The values obtained are approaching those of hot
isostatically pressed samples.Comment: 12 pages, 1 table, 4 figures, accepted in Applied Physics Letter
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