2,105 research outputs found
Prototype solar power satellite options
The choice of options for the prototype solar power satellite is addressed relative to risk and cost. Emphasis is placed on the reduction of the risk of failure. Risk is the program cost multiplied by the reduction in probability of program success due to the risky action. Four classes of risk are identified. It is suggested that prototyping would reduce the technical risk as well as reduce the effects of the other three types of risk by allowing them to be quantified earlier. Prototype demonstration requirements addressed include electromagnetic power link feasibility demonstration, component integration verification, construction technology verification, and cost performance verification. Specific prototype requirements are listed and prototyping options are given in tabular form
High-power microwave optics for flexible power transmission systems
A large concave microwave mirror near the transmitter can magnify the apparent size of the Earth as seen from a phased array, and vice versa, permitting a small phased array to be coupled to a small rectenna while preserving the transmission efficiency (the reflection loss is slight) and peak power densities characteristic of the reference system. This augmentation of the phased array aperture with a large mirror gives the system greater resolution (in the optical sense), and opens new degrees of freedom in SPS design. The consequences of such an approach for a prototype satellite were explored. Its consequences for a mature SPS are discussed
Rolling and sliding of a nanorod between two planes: Tribological regimes and control of friction
The motion of a cylindrical crystalline nanoparticle sandwiched between two
crystalline planes, one stationary and the other pulled at a constant velocity
and pressed down by a normal load, is considered theoretically using a planar
model. The results of our model calculations show that, depending on load and
velocity, the nanoparticle can be either rolling or sliding. At sufficiently
high normal loads, several sliding states characterized by different friction
forces can coexist, corresponding to different orientations of the
nanoparticle, and allowing one to have low or high friction at the same pulling
velocity and normal load.Comment: 5 figure
Eighty years of food-web response to interannual variation in discharge recorded in river diatom frustules from an ocean sediment core.
Little is known about the importance of food-web processes as controls of river primary production due to the paucity of both long-term studies and of depositional environments which would allow retrospective fossil analysis. To investigate how freshwater algal production in the Eel River, northern California, varied over eight decades, we quantified siliceous shells (frustules) of freshwater diatoms from a well-dated undisturbed sediment core in a nearshore marine environment. Abundances of freshwater diatom frustules exported to Eel Canyon sediment from 1988 to 2001 were positively correlated with annual biomass of Cladophora surveyed over these years in upper portions of the Eel basin. Over 28 years of contemporary field research, peak algal biomass was generally higher in summers following bankfull, bed-scouring winter floods. Field surveys and experiments suggested that bed-mobilizing floods scour away overwintering grazers, releasing algae from spring and early summer grazing. During wet years, growth conditions for algae could also be enhanced by increased nutrient loading from the watershed, or by sustained summer base flows. Total annual rainfall and frustule densities in laminae over a longer 83-year record were weakly and negatively correlated, however, suggesting that positive effects of floods on annual algal production were primarily mediated by "top-down" (consumer release) rather than "bottom-up" (growth promoting) controls
Molecular Motor Constructed from a Double-Walled Carbon Nanotube Driven by Axially Varying Voltage
A new molecular motor is conceptually constructed from a double-walled carbon
nanotube (DWNT) consisting of a long inner single-walled carbon nanotube (SWNT)
and a short outer SWNT with different chirality. The interaction between inner
and outer tubes is the sum of the Lennard-Jones potentials between carbon atoms
in inner tube and those in outer one. Within the framework of
Smoluchowski-Feynman ratchet, it is theoretically shown that this system in an
isothermal bath will exhibit a unidirectional rotation in the presence of a
varying axial electrical voltage.Comment: 11 pages + 3 figure
Ultra-high–strength Bainitic Steels
Novel bainitic microstructures, consisting of slender ferrite plates (tens of nm) in a matrix of retained austenite, have reported maximum yield strength of 1.4 GPa, ultimate tensile strength of 2.2 GPa, 30% ductility and respectable levels of fracture toughness (∼51 MPa m0.5). The unusual combination of properties is attributed to the fine bainitic plates and the presence of retained austenite in the microstructure.The authors acknowledge financial support from the
Spanish Ministerio de Educación y Ciencia for the financial
support in the form of Ramón y Cajal contracts (RyC 2002
and 2004 respectively). Some of this work was carried out
under the auspices of an EPSRC/MOD sponsored project
on bainitic steels at the University of Cambridge; we are
extremely grateful for this support over a period of three
years. The authors are extremely grateful to Prof. H. K. D.Peer reviewe
Quantum gears: a simple mechanical system in the quantum regime
Abstract. The quantum mechanics of a simple mechanical system is considered. A group of gears can serve as a model for several different systems such as an artifically constructed nanomechanical device or a group of ring molecules. It is shown that the classical motion of the gears in which the angular velocities are locked together does not correspond to
Anopheles stephensi p38 MAPK signaling regulates innate immunity and bioenergetics during Plasmodium falciparum infection.
BackgroundFruit flies and mammals protect themselves against infection by mounting immune and metabolic responses that must be balanced against the metabolic needs of the pathogens. In this context, p38 mitogen-activated protein kinase (MAPK)-dependent signaling is critical to regulating both innate immunity and metabolism during infection. Accordingly, we asked to what extent the Asian malaria mosquito Anopheles stephensi utilizes p38 MAPK signaling during infection with the human malaria parasite Plasmodium falciparum.MethodsA. stephensi p38 MAPK (AsP38 MAPK) was identified and patterns of signaling in vitro and in vivo (midgut) were analyzed using phospho-specific antibodies and small molecule inhibitors. Functional effects of AsP38 MAPK inhibition were assessed using P. falciparum infection, quantitative real-time PCR, assays for reactive oxygen species and survivorship under oxidative stress, proteomics, and biochemical analyses.ResultsThe genome of A. stephensi encodes a single p38 MAPK that is activated in the midgut in response to parasite infection. Inhibition of AsP38 MAPK signaling significantly reduced P. falciparum sporogonic development. This phenotype was associated with AsP38 MAPK regulation of mitochondrial physiology and stress responses in the midgut epithelium, a tissue critical for parasite development. Specifically, inhibition of AsP38 MAPK resulted in reduction in mosquito protein synthesis machinery, a shift in glucose metabolism, reduced mitochondrial metabolism, enhanced production of mitochondrial reactive oxygen species, induction of an array of anti-parasite effector genes, and decreased resistance to oxidative stress-mediated damage. Hence, P. falciparum-induced activation of AsP38 MAPK in the midgut facilitates parasite infection through a combination of reduced anti-parasite immune defenses and enhanced host protein synthesis and bioenergetics to minimize the impact of infection on the host and to maximize parasite survival, and ultimately, transmission.ConclusionsThese observations suggest that, as in mammals, innate immunity and mitochondrial responses are integrated in mosquitoes and that AsP38 MAPK-dependent signaling facilitates mosquito survival during parasite infection, a fact that may attest to the relatively longer evolutionary relationship of these parasites with their invertebrate compared to their vertebrate hosts. On a practical level, improved understanding of the balances and trade-offs between resistance and metabolism could be leveraged to generate fit, resistant mosquitoes for malaria control
- …