590 research outputs found
Mastoparan binding induces a structural change affecting both the N-terminal and C-terminal domains of calmodulin A 113Cd-NMR study
Abstract113Cd-NMR studies of solutions of cadmium-loaded calmodulin (Cd4CaM) and the tetradecapeptide mastoparan in different ratios show that mastoparan binds to Cd4CaM with high affinity. The off-rate of proteinbound mastoparan is found to be 40 s−1 or less. The binding of one molecule of mastoparan to Cd4CaM is observed to affect all four metal-binding sites, indicating that both the N-terminal and C-terminal globular domains of the protein undergo conformational changes
Kinetics of Intramolecular Chemical Exchange by Initial Growth Rates of Spin Saturation Transfer Difference Experiments (SSTD NMR)
We report here the Initial Growth Rates SSTD NMR method, as a new powerful tool to obtain the kinetic parameters of intramolecular chemical exchange in challenging small organic and organometallic molecules
Convergence and Divergence: A Comparison between the Nordic School Curricula
The aim of this article is to compare ethics and morality in the school systems in Denmark, Finland, Iceland, Norway and Sweden. What similarities and differences on ethical issues and values are to be found in the five countries? With a background knowledge in the Swedish curriculum, we want to study democracy, multiculturalism and human rights based on other countries’ curricula. Traditional theories and frameworks from literature on ethics and morality, for instance Begley’s frame of theory, and educational policy documents have been studied to understand the concepts in the school system. By using document analysis we have put this together to reach the aim of the study, which has a Nordic perspective, not only a Scandinavian one, which is the most usual ones. The main results are that there are both similarities and differences between the countries, but the Nordic countries regarding ethics and morality have especially to consider the main concepts democracy, multiculturalism and human rights in the school systems. Even if there are many similarities between the Nordic countries when it comes to democracy, multiculturalism and human rights there are differences between the Nordic countries how related concepts have been expressed
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