Lindsay Crawford's 'Impossible Demand'? The Southern Irish Dimension of the Independent Orange Project

The Magheramorne Manifesto of the Independent Orange Order has been hailed as a bold attempt from an unlikely quarter to positively address the sectarian divisions and regional polarisation of early 20th century Ireland. But the Order's leading light, Lindsay Crawford, has also been indicted for formulating an 'empty radicalism' which demanded changes in the field of education that it was impossible for the Catholic community to accept. This working paper reassesses Crawford's ideological project in the light of hitherto underused sources of evidence. It highlights convergence between Crawford's thinking and that of 'Irish Ireland' activists in movements such as the Gaelic League and Sinn Fein. It argues that heterodox educational views were prevalent to a significant extent among the Irish Irelanders to whom Crawford looked for a positive response to his national regeneration project. The case is also made that, in the absence of unanimous acceptance of their desirability among lay Catholics, the support of Protestants - and particularly that of Crawford's fellow Irish Anglicans - provided existing school management arrangements with a vital source of sustenance.

Physioacoustic Therapy: Placebo Effect on Recovery From Exercise-Induced Muscle Damage

We evaluated claims that physioacoustic therapy can enhance muscle healing following damaging exercise. Untrained subjects were randomly assigned to control (C), placebo (P) or treatment (T) groups. All groups performed 70 eccentric triceps contractions followed by; no treatment (C), sham physioacoustic treatment (P), or actual physioacoustic therapy (T) on days 1–4 post-exercise. Muscle soreness and isometric and concentric triceps peak torque were determined preexercise and on days 1–4 and 7 post-exercise. The T group received physioacoustic therapy for 30 min/day on the treatment days. The P group believed they received physioacoustic therapy, although the chairs were turned off. Peak torques were depressed (P \u3c 0.05) on days 1–3 in all groups and returned to pre-exercise values by days 4–7 in both P and T groups. C group peak torques remained depressed (P \u3c 0.05) through day 7. Soreness was elevated (P \u3c 0.05) in all groups on days 1–2 post-exercise. P and T groups reported no soreness by day 3 while the C group remained sore (P \u3c 0.05) through days 3–4. The T group recovered soreness and force faster than C but at a similar rate to the P group. The effectiveness of physioacoustic therapy in enhancing post-exercise muscle healing may be attributable to a placebo effect

Physioacoustic Therapy: Placebo Effect on Recovery From Exercise-Induced Muscle Damage

We evaluated claims that physioacoustic therapy can enhance muscle healing following damaging exercise. Untrained subjects were randomly assigned to control (C), placebo (P) or treatment (T) groups. All groups performed 70 eccentric triceps contractions followed by; no treatment (C), sham physioacoustic treatment (P), or actual physioacoustic therapy (T) on days 1–4 post-exercise. Muscle soreness and isometric and concentric triceps peak torque were determined preexercise and on days 1–4 and 7 post-exercise. The T group received physioacoustic therapy for 30 min/day on the treatment days. The P group believed they received physioacoustic therapy, although the chairs were turned off. Peak torques were depressed (P \u3c 0.05) on days 1–3 in all groups and returned to pre-exercise values by days 4–7 in both P and T groups. C group peak torques remained depressed (P \u3c 0.05) through day 7. Soreness was elevated (P \u3c 0.05) in all groups on days 1–2 post-exercise. P and T groups reported no soreness by day 3 while the C group remained sore (P \u3c 0.05) through days 3–4. The T group recovered soreness and force faster than C but at a similar rate to the P group. The effectiveness of physioacoustic therapy in enhancing post-exercise muscle healing may be attributable to a placebo effect

Wellbeing and Nurture: Physical and Emotional Security in Childhood

While there is increasing concern about developing and reinforcing children’s physical and emotional security, researchers have been busy working out the actual mechanics, even at the cellular level, of how this can be achieved. This report will provide a concise update on what is known about optimising children’s wellbeing and security in childhood and far beyond. In examining the ways in which children grow and develop, we can learn from that because their physical and emotional wellbeing and therefore that of our future society will depend on it. This report represents what we have learned and we hope that it will contribute in a small way to the making of the brave new ‘post-Covid’ world

Prevalence of Disorders Recorded in Dogs Attending Primary-Care Veterinary Practices in England

Purebred dog health is thought to be compromised by an increasing occurence of inherited diseases but inadequate prevalence data on common disorders have hampered efforts to prioritise health reforms. Analysis of primary veterinary practice clinical data has been proposed for reliable estimation of disorder prevalence in dogs. Electronic patient record (EPR) data were collected on 148,741 dogs attending 93 clinics across central and south-eastern England. Analysis in detail of a random sample of EPRs relating to 3,884 dogs from 89 clinics identified the most frequently recorded disorders as otitis externa (prevalence 10.2%, 95% CI: 9.1-11.3), periodontal disease (9.3%, 95% CI: 8.3-10.3) and anal sac impaction (7.1%, 95% CI: 6.1-8.1). Using syndromic classification, the most prevalent body location affected was the head-and-neck (32.8%, 95% CI: 30.7-34.9), the most prevalent organ system affected was the integument (36.3%, 95% CI: 33.9-38.6) and the most prevalent pathophysiologic process diagnosed was inflammation (32.1%, 95% CI: 29.8-34.3). Among the twenty most-frequently recorded disorders, purebred dogs had a significantly higher prevalence compared with crossbreds for three: otitis externa (P = 0.001), obesity (P = 0.006) and skin mass lesion (P = 0.033), and popular breeds differed significantly from each other in their prevalence for five: periodontal disease (P = 0.002), overgrown nails (P = 0.004), degenerative joint disease (P = 0.005), obesity (P = 0.001) and lipoma (P = 0.003). These results fill a crucial data gap in disorder prevalence information and assist with disorder prioritisation. The results suggest that, for maximal impact, breeding reforms should target commonly-diagnosed complex disorders that are amenable to genetic improvement and should place special focus on at-risk breeds. Future studies evaluating disorder severity and duration will augment the usefulness of the disorder prevalence information reported herein

Phaeoviruses discovered in kelp (Laminariales)

Phaeoviruses are latent double-stranded DNA viruses that insert their genomes into those of their brown algal (Phaeophyceae) hosts. So far these viruses are known only from members of the Ectocarpales, which are small and short-lived macroalgae. Here we report molecular and morphological evidence for a new Phaeovirus cluster, referred to as sub-group C, infecting kelps (Laminariales) of the genera Laminaria and Saccharina, which are ecologically and commercially important seaweeds. Epifluorescence and TEM observations indicate that the Laminaria digitata Virus (LdigV), the type species of sub-group C, targets the host nucleus for its genome replication, followed by gradual degradation of the chloroplast and assembly of virions in the cytoplasm of both vegetative and reproductive cells. This study is the first to describe phaeoviruses in kelp. In the field, these viruses infected two thirds of their host populations; however, their biological impact remains unknown

The Raine study had no evidence of significant perinatal selection bias after two decades of follow up: A longitudinal pregnancy cohort study

Background: Cohort studies may increase or decrease their selection bias as they progress through time. The Western Australian Pregnancy Cohort (Raine) Study has followed 2868 children for over two decades; from fetal into adult life. This paper analyses the cohort over time, assessing potential bias that may come and go with recruitment, retention and loss of participants. Methods: Linked data from all births in Western Australian over the 3 years the Raine Cohort was recruited were obtained to compare perinatal characteristics and subsequent health outcomes between the Western Australian (WA) contemporaneous birth population and the Raine Cohort at five time points. Perinatal exposure-outcome comparisons were employed to assess bias due to non-participation in Raine Study subsets. Results: There were demographic differences between the Raine Study cohort and its source population at recruitment with further changes across the period of follow up. Despite these differences, the pregnancy and infant data of those with continuing participation were not significantly different to the WA contemporaneous birth population. None of the exposure-outcome associations were significantly different to those in the WA general population at recruitment or at any cohort reviews suggesting no substantial recruitment or attrition bias. Conclusions: The Raine Study is valuable for association studies, even after 20 years of cohort reviews with increasing non-participation of cohort members. Non-participation has resulted in greater attrition of socially disadvantaged participants, however, exposure-outcome association analyses suggest that there is no apparent resulting selection bias

Ethnic Inequalities in Mortality: The Case of Arab-Americans

BACKGROUND: Although nearly 112 million residents of the United States belong to a non-white ethnic group, the literature about differences in health indicators across ethnic groups is limited almost exclusively to Hispanics. Features of the social experience of many ethnic groups including immigration, discrimination, and acculturation may plausibly influence mortality risk. We explored life expectancy and age-adjusted mortality risk of Arab-Americans (AAs), relative to non-Arab and non-Hispanic Whites in Michigan, the state with the largest per capita population of AAs in the US. METHODOLOGY/PRINCIPAL FINDINGS: Data were collected about all deaths to AAs and non-Arab and non-Hispanic Whites in Michigan between 1990 and 2007, and year 2000 census data were collected for population denominators. We calculated life expectancy, age-adjusted all-cause, cause-specific, and age-specific mortality rates stratified by ethnicity and gender among AAs and non-Arab and non-Hispanic Whites. Among AAs, life expectancies among men and women were 2.0 and 1.4 years lower than among non-Arab and non-Hispanic White men and women, respectively. AA men had higher mortality than non-Arab and non-Hispanic White men due to infectious diseases, chronic diseases, and homicide. AA women had higher mortality than non-Arab and non-Hispanic White women due to chronic diseases. CONCLUSIONS/SIGNIFICANCE: Despite better education and higher income, AAs have higher age-adjusted mortality risk than non-Arab and non-Hispanic Whites, particularly due to chronic diseases. Features specific to AA culture may explain some of these findings

Digitise This! A Quick and Easy Remote Sensing Method to Monitor the Daily Extent of Dredge Plumes

Technological advancements in remote sensing and GIS have improved natural resource managers’ abilities to monitor large-scale disturbances. In a time where many processes are heading towards automation, this study has regressed to simple techniques to bridge a gap found in the advancement of technology. The near-daily monitoring of dredge plume extent is common practice using Moderate Resolution Imaging Spectroradiometer (MODIS) imagery and associated algorithms to predict the total suspended solids (TSS) concentration in the surface waters originating from floods and dredge plumes. Unfortunately, these methods cannot determine the difference between dredge plume and benthic features in shallow, clear water. This case study at Barrow Island, Western Australia, uses hand digitising to demonstrate the ability of human interpretation to determine this difference with a level of confidence and compares the method to contemporary TSS methods. Hand digitising was quick, cheap and required very little training of staff to complete. Results of ANOSIM R statistics show remote sensing derived TSS provided similar spatial results if they were thresholded to at least 3 mg L-1. However, remote sensing derived TSS consistently provided false-positive readings of shallow benthic features as Plume with a threshold up to TSS of 6 mg L-1, and began providing false-negatives (excluding actual plume) at a threshold as low as 4 mg L-1. Semi-automated processes that estimate plume concentration and distinguish between plumes and shallow benthic features without the arbitrary nature of human interpretation would be preferred as a plume monitoring method. However, at this stage, the hand digitising method is very useful and is more accurate at determining plume boundaries over shallow benthic features and is accessible to all levels of management with basic training