2,353 research outputs found

    Possibility in the actual world

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    We haven't got a seat on the bus for you or All the seats are mine: Narratives and career transitions in professional golf

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    In this article we explore how the stories an athlete tells throughout life in sport affect her career transition experiences. We base our enquiry on a social constructionist conception of narrative theory which holds that storytelling is integral to the creation and maintenance of identity and sense of self. Life stories were gathered through interviews with two professional women golfers (Christiana and Kandy) over a six‐year period. Through a narrative analysis of structure and form we explored each participant’s stories of living in and withdrawing from professional golf. We suggest Christiana told monological performance‐oriented stories which, while aligning with the culture of elite sport, resulted in an exclusive athletic identity and foreclosure of alternative selves and roles. On withdrawal, Christiana experienced narrative wreckage, identity collapse, mental health difficulties and considerable psychological trauma. In contrast, Kandy told dialogical discovery‐oriented stories which, while being in tension with the dominant performance narrative, created and sustained a multidimensional identity and self. Her stories and identity remained intact, authentic and continuous on withdrawal from tournament golf and she experienced few psychological problems

    Underwater tunable organ-pipe sound source

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    Author Posting. © Acoustical Society of America, 2007. This article is posted here by permission of Acoustical Society of America for personal use, not for redistribution. The definitive version was published in Journal of the Acoustical Society of America 122 (2007): 777-785, doi:10.1121/1.2751268.A highly efficient frequency-controlled sound source based on a tunable high-Q underwater acoustic resonator is described. The required spectrum width was achieved by transmitting a linear frequency-modulated signal and simultaneously tuning the resonance frequency, keeping the sound source in resonance at the instantaneous frequency of the signal transmitted. Such sound sources have applications in ocean-acoustic tomography and deep-penetration seismic tomography. Mathematical analysis and numerical simulation show the Helmholtz resonator's ability for instant resonant frequency switching and quick adjustment of its resonant frequency to the instantaneous frequency signal. The concept of a quick frequency adjustment filter is considered. The discussion includes the simplest lumped resonant source as well as the complicated distributed system of a tunable organ pipe. A numerical model of the tunable organ pipe is shown to have a form similar to a transmission line segment. This provides a general form for the principal results, which can be applied to tunable resonators of a different physical nature. The numerical simulation shows that the “state-switched” concept also works in the high-Q tunable organ pipe, and the speed of frequency sweeping in a high-Q tunable organ pipe is analyzed. The simulation results were applied to a projector design for ocean-acoustic tomography.The work was supported by ONR

    A sound projector for acoustic tomography and global ocean monitoring

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    Author Posting. © IEEE, 2003. This article is posted here by permission of IEEE for personal use, not for redistribution. The definitive version was published in IEEE Journal of Oceanic Engineering 28 (2003): 174-185, doi:10.1109/JOE.2003.811888.Long-range underwater acoustic systems, such as those used in ocean acoustic tomography, require low-frequency signals covering a broad frequency band. To meet this requirement, a novel design based on of a tunable narrow-band high-efficiency sound projector has been exploited. The projector transmits a frequency sweep signal by mechanically tuning a resonator tube (or organ pipe) to match the frequency and phase of a reference signal. The resonator tube projector consists of a symmetrical pressure-balanced Tonpilz driver placed between two coaxially mounted tubes. The Tonpilz acoustical driver is composed of two pistons separated by preloaded ceramic stacks. The resonant tube is a simple. efficient, narrow-band, medium-output projector that operates at any ocean depth. Both projector tubes have slots (or vents), which are progressively covered or uncovered by sliding coaxial tubular sleeves. The frequency varies with the sleeves position. A computer-controlled electromechanical actuator moves the cylindrical sleeves along the tubes, keeping the projector in resonance at the instantaneous frequency of a swept frequency signal. The actuator smoothly tunes the frequency of the resonator tube in the bandwidth of 200 to 300 Hz during a 135-s transmission. A computer synthesizes the linear frequency-modulated signal; compares the phase between transmitted and reference signals; and, using a phase-lock loop (PLL) system, keeps the resonator tube frequency in resonance with the driver frequency. The estimated PLL precision is better than 3 phase error. The system was analyzed by means of finite element analysis and electrical equivalent circuit simulation. The projector prototype was first tested at theWoods Hole Oceanographic Institution (WHOI) dock inWoods Hole, MA and later in the Pacific Ocean during a voyage of the R/V “Point Sur,” November 2001.This work was supported by Office of Naval Research (ONR) under Small Business Innovation Research (SBIR) Program Topic OSD97-00

    1A. Thyroid hormone receptors in GtoPdb v.2023.1

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    Thyroid hormone receptors (TRs, nomenclature as agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [12, 2]) are nuclear hormone receptors of the NR1A family, with diverse roles regulating macronutrient metabolism, cognition and cardiovascular homeostasis. TRs are activated by thyroxine (T4) and thyroid hormone (triiodothyronine). Once activated by a ligand, the receptor acts as a transcription factor either as a monomer, homodimer or heterodimer with members of the retinoid X receptor family. NH-3 has been described as an antagonist at TRs with modest selectivity for TRβ [42]

    1A. Thyroid hormone receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

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    Thyroid hormone receptors (TRs, nomenclature as agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [10]) are nuclear hormone receptors of the NR1A family, with diverse roles regulating macronutrient metabolism, cognition and cardiovascular homeostasis. TRs are activated by thyroxine (T4) and thyroid hormone (triiodothyronine). Once activated by a ligand, the receptor acts as a transcription factor either as a monomer, homodimer or heterodimer with members of the retinoid X receptor family. NH-3 has been described as an antagonist at TRs with modest selectivity for TRβ [38]

    Radically reframing studies on neurobiology and socioeconomic circumstances: A call for social justice-oriented neuroscience

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    Socioeconomic circumstances are associated with symptoms and diagnostic status of nearly all mental health conditions. Given these robust relationships, neuroscientists have attempted to elucidate how socioeconomic-based adversity “gets under the skin.” Historically, this work emphasized individual proxies of socioeconomic position (e.g., income, education), ignoring the effects of broader socioeconomic contexts (e.g., neighborhood socioeconomic disadvantage) which may uniquely contribute to chronic stress. This omission represented a disconnect between neuroscience and other allied fields that have recognized health is undeniably linked to interactions between systems of power and individual characteristics. More recently, neuroscience work has considered how sociopolitical context affects brain structure and function; however, the products of this exciting line of research have lacked critical sociological and historical perspectives. While empirical evidence on this topic is burgeoning, the cultural, ethical, societal, and legal implications of this work have been elusive. Although the mechanisms by which socioeconomic circumstances impact brain structure and function may be similar across people, not everyone is exposed to these factors at similar rates. Individuals from ethnoracially minoritized groups are disproportionally exposed to neighborhood disadvantage. Thus, socioeconomic inequities examined in neuroscience research are undergirding with other forms of oppression, namely structural racism. We utilize a holistic, interdisciplinary approach to interpret findings from neuroscience research and interweave relevant theories from the fields of public health, social sciences, and Black feminist thought. In this perspective piece, we discuss the complex relationship that continues to exist between academic institutions and underserved surrounding communities, acknowledging the areas in which neuroscience research has historically harmed and/or excluded structurally disadvantaged communities. We conclude by envisioning how this work can be used; not just to inform policymakers, but also to engage and partner with communities and shape the future direction of human neuroscience research

    Materials and Methods Useful to Affect Growth and Development of Lepidoptera Larvae

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    The present invention provides materials and methods related to causing insect resistance in plants. Specifically, the present invention provides nucleic acid compounds which encode a teratocyte secreted protein (TSP) which is capable of causing inhibition of growth and developmental arrest in Lepidoptera larvae. Cells and plants (including plant parts, seeds, embryos, etc.) comprising the nucleic acid compounds are also within the scope of the present invention. The present invention also provides amino acid compounds encoded by the nucleic acid compounds of the present invention, as well as methods to induce larval developmental arrest, methods to produce the nucleic acid and amino acid compounds, and methods to inhibit crop damage due to Lepidoptera infestation
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