National Survey of Extension 4-H Professionals\u27 Perceptions of Professional Development Factors

Our study describes factors that influence Extension 4-H professionals\u27 likelihood of participating in a professional development experience. We used a work group–developed survey to measure the level of influence of nine factors. Through convenience sampling, we obtained 558 responses from 4-H professionals representing all regions of the country and multiple job roles. Cost, location, networking, personal needs, and time were strongly influential. Differences related to job role and years of job experience existed. Our major recommendation is that those creating professional development experiences for 4-H professionals consider both the major influential factors involved and factors of adult development, such as the need for self-directed learning

The RunSmart Training Program: Effect on Oxygen Consumption and Lower Extremity Biomechanics During Running

As recreational running continues to gain popularity, more individuals are seeking ways to improve running performance. RunSmart is a running intervention program designed to enhance a runner’s form. In addition to correcting flaws in a runner’s form, RunSmart offers the opportunity for runners to continue a regular regimen while slowly integrating changes in form. The purpose of this case series was twofold: to determine if the RunSmart program coincides with improvements in oxygen consumption (VO2), a variable often associated with better running performance times, and to evaluate the RunSmart program in regard to enhancing gait biomechanics. Five recreational runners volunteered to participate in this program. Subjects initially reported to the clinic for an initial submaximal VO2 treadmill test and lower extremity biomechanical analysis. After the initial testing session, each subject attended one session of one-on-one individualized RunSmart instruction per week for 6 weeks. At the first RunSmart session, subjects received a biomechanical analysis to determine their foot strike pattern and areas of muscular weakness and range of motion limitations. Throughout the 6-week run-ning program, participants ran 5 days every week for predetermined times each day; 2 runs every week were designated as interval training runs. Subjects then underwent a follow-up submaximal VO2 treadmill test and lower extremity biomechanical analysis at the end of 6 weeks. Descriptive statistics were used to assess data pertaining to VO2 and biomechanical analysis and compare initial and follow-up testing sessions. Following completion of the RunSmart program, subjects demonstrated improvements in VO2 and also improved several biomechanical factors related to the lower extremity running gait. Based on the results from this case series, the RunSmart training program may have the potential to change a runner’s form and improve VO2, thus resulting in improved distance running times. However, this is speculation given the nonexperimental nature of this case series. Future research on this topic should include a greater number of participants in randomized controlled trials on injury prevention and running efficiency

The Lantern Vol. 39, No. 2, Spring 1973

• Days of Rain • Reflections On Clifton, New Jersey • Interlude • Window Scene • Eh! • Odyssey of Malcolm • Tuna on Toast • The Second Avenue Bus • Salutation of the Dawn • So Say Something • Mood • Moriarty\u27s Lament • I\u27ve Been a Lonely Gypsy • Change • Cool Ray • The Thinker • A Southern Sunsethttps://digitalcommons.ursinus.edu/lantern/1102/thumbnail.jp

The Lantern Vol. 38, No. 2, Spring 1972

• Summer II • For a True Romantic • The Lyre Neglected • Hands • To a Friend • Sleep • The Wind\u27s Confusing Sounds • The Garden • The Child Has Come Among Us • The River and the Sea • The Ice • La Lamentation de la Fleur • Nous Sommes • Upon Becoming • See! • Feeling November • Transience • Clear • Isotopes of Reality • Just Yesterday • Emergence • Push • The Way Love Starts • Poetic Prosy • An Agreement • Spring 1930 • The Summers of \u2759, \u2760, \u2761 • Ode to Optometry • The Easter Bunny - Noble Beasthttps://digitalcommons.ursinus.edu/lantern/1100/thumbnail.jp

The Vehicle, Spring 2010

Table of Contents ForgettingRashelle McNairpage 34 MuseMary Lieskepage 35 My CompulsionAshton Tembypage 38 MemoryKate Vandermeerpage 41 Killmercialize MeGreg Petersonpage 42 PenJake Smithpage 46 GrassKate Vandermeerpage 48 Character CreationMary Lieskepage 52 Ring Around TheKim Hunter-Perkinspage 54 The Great Cursive ScareJake Smithpage 55 OpiateDoug Urbanskipage 61 What Happens to Little Girls...Jennifer O\u27Neilpage 63 Poetry Sunny DaysRyan Poolpage 2 AtlantisDoug Urbanskipage 4 Garbage CityKate Vandermeerpage 6 Fat Girl ThongsKim Hunter-Perkinspage 7 MercilessRosalia Pecorapage 19 ChemistryMary Lieskepage 20 He-Who-Stopped-TalkingJustin Sudkamppage 22 In Which Iris Contemplates a Barren EarthSean Slatterypage 24 At the Bottom of the WorldNick Canadaypage 27 Dogma: Mush!Scott Maypage 28 ThiefMary Lieskepage 29 Prose Coming HomeDoug Urbanskipage 8 DodoDan Davispage 31 The Poet in the PedestrianScott Maypage 37 Toxic RainJacob Swansonpage 40 What\u27s Your Greatest Fear?Justine Fittonpage 43 Soul VoiceHolly Thomaspage 49 Conversations with a SniperKim Hunter-Perkinspage 56 LettersDaniel Paquinpage 65 Art San Marcos, MexicoKate Vandermeercover Contemplation of the World\u27s EndNicholas Giffordpage 18 Little Lady SitsSarah Hadwigerpage 26 MoodAlycia Rockeypage 30 Four Ducks in a RowMegan Mathypage 36 The Daily EasternBen Tillerypage 39 BirdsAlycia Rockeypage 45 March of the BugsMegan Mathypage 47 Mexico Work ExperienceKate Vandermeerpage 53 Feather and JewelsAlycia Rockeypage 60 The ForgottenMegan Mathypage 64 Special Features Fall 2009-Spring 2010 Vehicle Award Winnerspage 1 James K. Johnson Creative Writing Awardpage 74 Kim Hunter-PerkinsWinning Entries (Poetry)page 75 Clint WalkerWinning Entry (Fiction)page 86 Faculty Spotlight: Professor Jason Brownpage 99 About the Contributorspage 106 About the Editorspage 110https://thekeep.eiu.edu/vehicle/1093/thumbnail.jp

Pre-hospital management protocols and perceived difficulty in diagnosing acute heart failure

Aim To illustrate the pre-hospital management arsenals and protocols in different EMS units, and to estimate the perceived difficulty of diagnosing suspected acute heart failure (AHF) compared with other common pre-hospital conditions. Methods and results A multinational survey included 104 emergency medical service (EMS) regions from 18 countries. Diagnostic and therapeutic arsenals related to AHF management were reported for each type of EMS unit. The prevalence and contents of management protocols for common medical conditions treated pre-hospitally was collected. The perceived difficulty of diagnosing AHF and other medical conditions by emergency medical dispatchers and EMS personnel was interrogated. Ultrasound devices and point-of-care testing were available in advanced life support and helicopter EMS units in fewer than 25% of EMS regions. AHF protocols were present in 80.8% of regions. Protocols for ST-elevation myocardial infarction, chest pain, and dyspnoea were present in 95.2, 80.8, and 76.0% of EMS regions, respectively. Protocolized diagnostic actions for AHF management included 12-lead electrocardiogram (92.1% of regions), ultrasound examination (16.0%), and point-of-care testings for troponin and BNP (6.0 and 3.5%). Therapeutic actions included supplementary oxygen (93.2%), non-invasive ventilation (80.7%), intravenous furosemide, opiates, nitroglycerine (69.0, 68.6, and 57.0%), and intubation 71.5%. Diagnosing suspected AHF was considered easy to moderate by EMS personnel and moderate to difficult by emergency medical dispatchers (without significant differences between de novo and decompensated heart failure). In both settings, diagnosis of suspected AHF was considered easier than pulmonary embolism and more difficult than ST-elevation myocardial infarction, asthma, and stroke. Conclusions The prevalence of AHF protocols is rather high but the contents seem to vary. Difficulty of diagnosing suspected AHF seems to be moderate compared with other pre-hospital conditions

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin