Measurement of the η\eta -η′\eta' mixing angle in π−\pi^{-} and K−K^{-} beams with GAMS-4π4\pi Setup

The results of mixing angle measurement for $\eta'$, $\eta$ mesons generated in charge exchange reactions with $\pi^{-}$ and $K^{-}$ beams are preseneted. When the $\eta'$, $\eta$ mesons are described in nonstrange(NS)--strange(S) quark basis the $\pi^{-}$ and $K^{-}$ beams allow to study $|\eta_{q}>$ and $|\eta_{s}>$ parts of the meson wave function. The cross section ratio at $t'=0$ (GeV/c)$^{2}$ in the $\pi^{-}$ beam is $R_{\pi}(\eta'/\eta)= 0.56 \pm 0.04$, results in mixing angle $\phi_{P} = (36.8 \pm 1.)^{o}$. For $K^{-}$ beam the ratio is $R_{K}(\eta'/\eta)= 1.30 \pm 0.16$. It was found that gluonium content in $\eta'$ is $\sin^{2}\psi_{G}= 0.15 \pm 0.06$. The experiment was carried out with GAMS-4$\pi$ Setup.Comment: 6 pages, 4 figures, 1 table, to be submitted in European physical journal C. Minor changes, the Bibliography extende

A software system for pathological voice acoustic analysis

International audienceA software system for pathological voice analysis using only the resources of a personal computer with a sound card is proposed. The system is written on the basis of specific methods and algorithms for pathological voice analysis and allows evaluation of: 1) Pitch period (To); 2) Degree of unvoiceness; 3) Pitch perturbation and amplitude perturbation quotients; 4) Dissimilarity of surfaces of the pitch pulses; 5) Ratio aperiodic/periodic components in cepstra; 6) Ratio {energy in the cepstral pitch pulse}-to-{total cepstral energy}; 7) Harmonics-to-noise ratio; 8) Degree of hoarseness; 9) Ratio low-to-high frequency energies; 10) Glottal Closing Quotient. The voices of 400 persons were analyzed - 100 (50 females/50 males) normal speakers and 300 (100 females/200 males) patients. The statistical analysis shows very significant changes in PPQ, DH, DPP, DUV, APR, HNR and PECM, and significant changes in APQ and CQ

Functional Performance Testing in Ice Hockey: the Role of the Single Leg, Medial Countermovement Jump

Due to the physical nature of the game, injuries are common in ice hockey. Injury rates have been difficult to interpret due to the inconsistencies in the definitions of injury and athlete exposure. Consensus statements on injury definitions have been developed for sports such as soccer and rugby but have not been established in ice hockey. Furthermore, many different off-ice tests are performed, but a hockey-specific performance test has not been promoted. Accordingly, the objective for this thesis was to investigate injury rates, injury definition, athlete exposure and injury type in men’s ice hockey, and providing information on a practical test practitioners can use to monitor fatigue and measure performance. This was achieved through three research projects. An integrative literature review was conducted to suggest a specific definition of injury and athlete exposure (Chapter 2). This study identified that the International Ice Hockey Federation’s definition of injury is preferred based on the clarity and relevance of the injury description and that the preferred athlete exposure metric is player game-hours based on accuracy and ease of use. In addition, lower extremity injuries were identified as common and costly in men’s ice hockey. The single leg, medial countermovement jump was identified as an appropriate hockey-specific performance test. This jump enables objective measures of frontal plane force and power and is particularly applicable for ice hockey players given that ice skating involves applying lateral forces. All twelve parameters of the jump showed moderate to excellent reliability (Chapters 3) suggesting that this jump is a reliable test for assessing frontal plane force and power in ice hockey players. Finally, normative values and asymmetry indices were presented in ninety-one male youth hockey players aged 10–18 years (Chapter 4). In conclusion, lower extremity injuries are common in hockey and injury rates are difficult to interpret as the definition is not consistent. The single leg, medial countermovement jump is an appropriate functional test for measuring skating performance. Ice hockey performance staff can use this evidence-based research to measure performance, monitor fatigue, and document recovery from injury

Everolimus-induced pneumonitis associates with favourable outcome in patients with metastatic renal cell carcinoma

Background: Mammalian target of rapamycin inhibitors may induce pneumonitis. We analysed the association of pneumonitis with outcomes in everolimus treated metastatic renal cell carcinoma (mRCC) patients. Patients and methods: Eighty-five mRCC patients received everolimus at Helsinki University Hospital (cohort A). Computed tomography (CT) verified pneumonitis was correlated with outcome using Kaplan-Meier, Cox regression and logistic regression. An independent cohort of 148 everolimus treated mRCC patients (cohort B) at Aarhus University Hospital was assessed for validation. Results: In cohort A, CT-verified pneumonitis (N = 29, 34.1%) was associated with improved overall survival (OS) (24.7 versus 8.5 months; P <0.001), progression-free survival (PFS) (5.5 versus 3.2 months; P = 0.002) and clinical benefit rate (CBR) 57.1% versus 24.1% (P = 0.003). In multivariate analyses pneumonitis was associated with improved OS (hazard ratio [HR], 0.22; 95% confidence interval [CI] 0.12-0.44; P <0.001), PFS (HR 0.37; 95% CI 0.21-0.66; P = 0.001) and CBR (odds ratio [OR] 4.11; 95% CI 1.42-11.95; P = 0.01). In cohort B, CT-verified pneumonitis (N = 29, 19.6%) was associated with improved OS (12.9 versus 6.0 months; P = 0.02), PFS (6.0 versus 2.8 months; P = 0.02) and CBR (79.3% versus 39.5%; P <0.001). In multivariate analyses pneumonitis was associated with improved OS (HR 0.58; 95% CI 0.36-0.94; P = 0.03), PFS (HR 0.61; 95% CI 0.39-0.95; P = 0.03) and CBR (OR 5.65; 95% CI 2.10-15.18; P = 0.001). In a combined multivariate analysis (N = 233), with pneumonitis as a time-dependent covariate, CT-verified pneumonitis was associated with longer OS (HR, 0.67; 95% CI 0.46-0.97; P = 0.03). Furthermore, in a landmark analysis, pneumonitis was associated with longer OS (17.4 versus 7.8 months; P = 0.01). Conclusions: Everolimus-induced pneumonitis is associated with improved outcome in patients with mRCC and may serve as a biomarker of everolimus efficacy. (C) 2017 Elsevier Ltd. All rights reserved.Peer reviewe

Muslimerne bag skærmen: Danske muslimers onlinefællesskaber

Artiklen undersøger forskellige typer af onlinefællesskaber blandt danske muslimer på Facebook og finder fire overordnede typer af fællesskaber: politisk aktivistiske, reaktivt religiøse, pragmatisk religiøse og velgørenhedsorienterede fællesskaber. En indholdsanalyse af fællesskabernes opslag og selvbeskrivelse klarlægger den enkelte fællesskabsklynges karakteristika. Gennem et online spørgeskema (N = 80) og interviews med spørgeskemarespondenter kortlægges brugernes syn på og brug af fællesskaberne i klyngerne. Herudover undersøges forestillingen om ”muslim” som efterkommernes stærkeste identitetskategori og deres prioritering af ummahen frem for det nationale tilhørsforhold. Artiklen finder, at hovedparten af respondenterne giver udtryk for det religiøse som del af privatsfæren, og at Facebookfællesskaberne derfor mere udgør interessefællesskaber end identitetsbærende fællesskaber

Analysis of Changes in the Total Lymphocyte and Eosinophil Count during Immunotherapy for Metastatic Renal Cell Carcinoma: Correlation with Response and Survival

The aims of this study were to analyze lymphocyte and eosinophil counts in consecutive peripheral blood samples taken during immunotherapy for metastatic renal cell carcinoma (mRCC) and to correlate the findings with objective response and survival. A total of 40 patients with mRCC who received immunotherapy with interleukin-2, interferon-α, and 5-fluorouracil were analyzed. Objective responses were observed in 14 patients, including 2 (5%) who showed a complete response (CR) and 12 (30%) who showed a partial response (PR). Eleven patients (27%) achieved stable disease (SD), and 15 patients (38%) had progressive disease (PD). Changes from baseline in the total lymphocyte counts were significantly higher in the responding patients (CR+PR+SD) than in the non-responding patients (PD) (p=0.017), but no difference was seen in the total eosinophil counts (p=0.275). Univariate analysis identified the Eastern Cooperative Oncology Group (ECOG) performance status (p=0.017), the presence of a primary renal tumor (p<0.001) and the peripheral lymphocyte counts at week 4 (p=0.034) as prognostic factors, but a low ECOG performance status (p=0.003) and the presence of a primary renal tumor (p=0.001) were identified as independent poor prognostic factors by multivariate analysis. This study provides further evidence that changes in blood lymphocyte counts may serve as an objective indicator of objective responses