13 research outputs found
The trends of BDs prevalence rates in Hunan and in China from 2005 to 2014.
<p>The trends of BDs prevalence rates in Hunan and in China from 2005 to 2014.</p
Size Modulation of Zirconium-Based Metal Organic Frameworks for Highly Efficient Phosphate Remediation
Eutrophication
of water bodies caused by the excessive phosphate discharge has constituted
a serious threat on a global scale. It is imperative to exploit new
advanced materials featuring abundant binding sites and high affinity
to achieve highly efficient and specific capture of phosphate from
polluted waters. Herein, water stable Zr-based metal organic frameworks
(MOFs, UiO-66) with rational structural design and size modulation
have been successfully synthesized based on a simple solvothermal
method for effective phosphate remediation. Impressively, the size
of the resulting UiO-66 particles can be effectively adjusted by simply
altering reaction time and the amount of acetic acid with the purpose
of understanding the crucial effect of structural design on the phosphate
capture performance. Representatively, UiO-66 particles with small
size demonstrates 415 mg/g of phosphate uptake capacity, outperforming
most of the previously reported phosphate adsorbents. Meanwhile, the
developed absorbents can rapidly reduce highly concentrated phosphate
to below the permitted level in drinking water within a few minutes.
More significantly, the current absorbents display remarkable phosphate
sorption selectivity against the common interfering ions, which can
be attributed to strong affinity between Zr–OH groups in UiO-66
and phosphate species. Furthermore, the spent UiO-66 particles can
be readily regenerated and reused for multiple sorption–desorption
cycles without obvious decrease in removal performance, rendering
them promising sustainable materials. Hence, the developed UiO-66
adsorbents hold significant prospects for phosphate sequestration
to mitigate the increasingly eutrophic problems
Perinatal outcomes and congenital heart defect prognosis in 53313 non-selected perinatal infants
<div><p>Objective</p><p>To evaluate perinatal outcomes and congenital heart defect (CHD) prognosis in a non-selected population.</p><p>Methods</p><p>The population-based surveillance data used in this assessment of CHDs were based on birth defect surveillance data collected from 2010–2012 in Liuyang City, China. Infants living with CHDs were followed up for 5 years to determine their prognosis. Prevalence, prenatal diagnosis, perinatal outcomes, and total and type-specific prognosis data were assessed using SPSS 18.0.</p><p>Results</p><p>In total, 190 CHD cases were identified among the 53313 included perinatal infants (PIs), indicating a CHD prevalence of 35.64 per 10000 PIs in this non-selected population. The five most frequently identified types of CHDs were ventricular septal defects (VSDs, 38.95%), atrial septal defects (ASDs, 15.79%), cardiomegaly (7.89%), tetralogy of Fallot (TOF, 5.79%), and atrioventricular septal defects (AVSDs, 5.26%). Of the 190 CHD cases, 110 (57.89%) were diagnosed prenatally, 30 (15.79%) were diagnosed with associated malformations, and 69 (36.32%) resulted in termination of pregnancy (TOP). Moreover, 15 (7.89%) PIs died within 7 days after delivery, and 42 (22.10%) died within 1 year. In contrast, 79 (41.58%) were still alive after 5 years. When TOP cases were included, the 5-year survival rate of PIs with prenatally detected CHDs was lower than that of PIs with postnatally detected CHDs (25.45% vs. 63.75%). The CHD subtype associated with the highest rate of infant (less than 1 year old) mortality was transposition of the great arteries (100%). The subtypes associated with higher 5-year survival rates were patent ductus arteriosus (80%), ASD (63.33%), VSD (52.70%) and AVSD (50%).</p><p>Conclusions</p><p>The rates of prenatal CHD detection and TOP were high in this study population, and the 5-year survival rate of PIs with CHDs was low. The government should strengthen efforts to educate pediatricians regarding this issue and provide financial assistance to improve the prognosis of infants living with CHDs, especially during the first year of life.</p></div
Perinatal outcomes and congenital heart defect prognosis in 53313 non-selected perinatal infants
<div><p>Objective</p><p>To evaluate perinatal outcomes and congenital heart defect (CHD) prognosis in a non-selected population.</p><p>Methods</p><p>The population-based surveillance data used in this assessment of CHDs were based on birth defect surveillance data collected from 2010–2012 in Liuyang City, China. Infants living with CHDs were followed up for 5 years to determine their prognosis. Prevalence, prenatal diagnosis, perinatal outcomes, and total and type-specific prognosis data were assessed using SPSS 18.0.</p><p>Results</p><p>In total, 190 CHD cases were identified among the 53313 included perinatal infants (PIs), indicating a CHD prevalence of 35.64 per 10000 PIs in this non-selected population. The five most frequently identified types of CHDs were ventricular septal defects (VSDs, 38.95%), atrial septal defects (ASDs, 15.79%), cardiomegaly (7.89%), tetralogy of Fallot (TOF, 5.79%), and atrioventricular septal defects (AVSDs, 5.26%). Of the 190 CHD cases, 110 (57.89%) were diagnosed prenatally, 30 (15.79%) were diagnosed with associated malformations, and 69 (36.32%) resulted in termination of pregnancy (TOP). Moreover, 15 (7.89%) PIs died within 7 days after delivery, and 42 (22.10%) died within 1 year. In contrast, 79 (41.58%) were still alive after 5 years. When TOP cases were included, the 5-year survival rate of PIs with prenatally detected CHDs was lower than that of PIs with postnatally detected CHDs (25.45% vs. 63.75%). The CHD subtype associated with the highest rate of infant (less than 1 year old) mortality was transposition of the great arteries (100%). The subtypes associated with higher 5-year survival rates were patent ductus arteriosus (80%), ASD (63.33%), VSD (52.70%) and AVSD (50%).</p><p>Conclusions</p><p>The rates of prenatal CHD detection and TOP were high in this study population, and the 5-year survival rate of PIs with CHDs was low. The government should strengthen efforts to educate pediatricians regarding this issue and provide financial assistance to improve the prognosis of infants living with CHDs, especially during the first year of life.</p></div
Outcomes and prognosis of infants with CHDs detected either prenatally or postnatally.
<p>*P<i><</i>0.001.</p
Comparison of outcomes and prognosis of infants with CHDs between Liuyang City and Guangdong Province.
<p>Comparison of outcomes and prognosis of infants with CHDs between Liuyang City and Guangdong Province.</p
Clinical management and follow-up of 190 CHD cases.
<p>Clinical management and follow-up of 190 CHD cases.</p
Spectrum of associated malformations in a non-selected population of 53313 PIs.
<p>Tri 21: trisomy 21 syndrome; SUR: single umbilical artery; Hyd/Ser: hydrothorax/seroperitoneum; DH: diaphragmatic hernia; FLV: fetal lateral ventriculomegaly; SK/CK: single kidney/compound kidney; NTD: neural tube defect; LCAL: lung cystic adenomatoid lesion; ELS: enlargement of the liver and spleen; TE: talipes equinovarus; HIS: internal heterogeneous syndrome; CDOS: congenital dysplasia of the skin; AA: accessory auricle; DE: diaphragmatic eventration; NRDS: neonatal respiratory distress syndrome.</p
Outcomes and prognosis of infants with CHDs detected either prenatally or postnatally.
<p>*P<i><</i>0.001.</p
NiFe-Layered Double Hydroxide Nanosheet Arrays Supported on Carbon Cloth for Highly Sensitive Detection of Nitrite
Excessive
uptake of nitrite has been proven to be detrimental to the ecological
system and human health. Hence, there is a rising requirement for
constructing effective electrochemical sensors to precisely monitor
the level of nitrite. In this work, NiFe-layered double hydroxide
nanosheet arrays (NiFe-LDH NSAs) have been successfully fabricated
on a carbon cloth (CC) substrate via a facile one-pot hydrothermal
route. By integrating the collective merits of macroporous CC and
NiFe-LDH NSAs such as superior electrical conductivity, striking synergistic
effect between the dual active components, enlarged electrochemically
active surface area, unique three-dimensional hierarchical porous
network characteristics, and fast charge transport and ion diffusion,
the proposed NiFe-LDH NSAs/CC architecture can be served as a self-supporting
sensor toward nitrite detection. As a consequence, the resulting NiFe-LDH
NSAs/CC electrode demonstrates superior nitrite sensing characteristics,
accompanied by broad linear range (5–1000 μM), quick
response rate (ca. 3 s), ultralow detection limit (0.02 μM),
and high sensitivity (803.6 μA·mM<sup>–1</sup>·cm<sup>–2</sup>). Meanwhile, the electrochemical sensor possesses
timeless stability, good reproducibility, and strong anti-interference
feature. Importantly, the resulting sensor can determine nitrite level
in tap and lake water with high recoveries, suggesting its feasibility
for practical applications. These findings show that the obtained
NiFe-LDH NSAs/CC electrode holds great prospect in highly sensitive
and specific detection of nitrite