36 research outputs found

    Documentare per le famiglie e con le famiglie nel nido d’infanzia

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    Attraverso la pratica della documentazione è stato possibile, da parte di un gruppo di insegnanti dei nidi del Comune di Pistoia, realizzare una sintesi virtuosa tra riflessione sulla pratica educativa e relazione partecipativa delle famiglie. La ricerca di idee e di modi nuovi di documentazione ha caratterizzato questo percorso e ha prodotto un modo di intendere la documentazione rivolta alle famiglie, intesa come occasione di incontro autentico e promozione culturale del servizio, che ha dato ampio spazio al protagonismo dei genitori

    Books, stories, and the imagination at Filastrocca: Case study of a preschool learning environment in Pistoia, Italy.

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    The progressive educational systems of some regions of Italyare becoming increasingly recognized by educators and researchers, including those from North America, seeking insight into diverse educational approaches from the international community. This paper represents a case study of Filastrocca (“Nursery Rhyme”), a preschool in the Tuscan city of Pistoia. Filastrocca proclaims a special mission related to books, storytelling, and the imagination, and appears to offer a unique environment that supports children’s active and enthusiastic engagement in complex literacy discussions and activities. The purpose of this paper is to provide a detailed description of the learning environment for language and literacy at the preschool. There is an emphasis on exploring what kinds of opportunities related to books, storytelling, and the imagination are providing to support and encourage young children and their families, and in examining how the learning environment reflects the mission of the school in fostering early childhood language and literacy

    Brucella abortus Strain RB51 Vaccine: Immune Response after Calfhood Vaccination and Field Investigation in Italian Cattle Population

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    Immune response to Brucella abortus strain RB51 vaccine was measured in cattle vaccinated at calfhood. After an increase at day 6 post-vaccination (pv), the antibody level recorded in the 10 vaccinated animals remained constant for two months, and then progressively decreased. All vaccinated animals remained negative from day 162 pv to the end of the study (day 300 pv). Only at days 13 and 14 pv the RB51-CFT showed 100% sensitivity (credibility interval (CI) 76.2%–100%). The results indicate that the possibility to use RB51-CFT for the identification of cattle vaccinated at calfhood with RB51 is limited in time. A field investigation was carried out on 26,975 sera collected on regional basis from the Italian cattle population. The study outcomes indicate that in case of RB51-CFT positive results observed in officially Brucellosis-free (OBF) areas and, in any case, when an illegal use of RB51 vaccine is suspected, the use of the RB51-CFT alone is not sufficient to identify all the vaccinated animals. The design of a more sophisticated diagnostic protocol including an epidemiological investigation, the use of RB51-CFT, and the use of the skin test with RB51 as antigen is deemed more appropriate for the identification of RB51 vaccinated animals

    Host cell traversal is important for progression of the malaria parasite through the dermis to the liver

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    The malaria sporozoite, the parasite stage transmitted by the mosquito, is delivered into the dermis and differentiates in the liver. Motile sporozoites can invade host cells by disrupting their plasma membrane and migrating through them (termed cell traversal), or by forming a parasite-cell junction and settling inside an intracellular vacuole (termed cell infection). Traversal of liver cells, observed for sporozoites in vivo, is thought to activate the sporozoite for infection of a final hepatocyte. Here, using Plasmodium berghei, we show that cell traversal is important in the host dermis for preventing sporozoite destruction by phagocytes and arrest by nonphagocytic cells. We also show that cell infection is a pathway that is masked, rather than activated, by cell traversal. We propose that the cell traversal activity of the sporozoite must be turned on for progression to the liver parenchyma, where it must be switched off for infection of a final hepatocyte.Inst Pasteur, Unite Biol & Genet Paludisme, F-75724 Paris 15, FranceUniversidade Federal de São Paulo, Dept Bioquim, BR-04044020 São Paulo, BrazilUniv Montpellier 2, CNRS, UMR 5539, F-34095 Montpellier 05, FranceMie Univ, Sch Med, Tsu, Mie 5140001, JapanUniversidade Federal de São Paulo, Dept Bioquim, BR-04044020 São Paulo, BrazilWeb of Scienc

    Acute Delta Hepatitis in Italy spanning three decades (1991–2019): Evidence for the effectiveness of the hepatitis B vaccination campaign

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    Updated incidence data of acute Delta virus hepatitis (HDV) are lacking worldwide. Our aim was to evaluate incidence of and risk factors for acute HDV in Italy after the introduction of the compulsory vaccination against hepatitis B virus (HBV) in 1991. Data were obtained from the National Surveillance System of acute viral hepatitis (SEIEVA). Independent predictors of HDV were assessed by logistic-regression analysis. The incidence of acute HDV per 1-million population declined from 3.2 cases in 1987 to 0.04 in 2019, parallel to that of acute HBV per 100,000 from 10.0 to 0.39 cases during the same period. The median age of cases increased from 27 years in the decade 1991-1999 to 44 years in the decade 2010-2019 (p < .001). Over the same period, the male/female ratio decreased from 3.8 to 2.1, the proportion of coinfections increased from 55% to 75% (p = .003) and that of HBsAg positive acute hepatitis tested for by IgM anti-HDV linearly decreased from 50.1% to 34.1% (p < .001). People born abroad accounted for 24.6% of cases in 2004-2010 and 32.1% in 2011-2019. In the period 2010-2019, risky sexual behaviour (O.R. 4.2; 95%CI: 1.4-12.8) was the sole independent predictor of acute HDV; conversely intravenous drug use was no longer associated (O.R. 1.25; 95%CI: 0.15-10.22) with this. In conclusion, HBV vaccination was an effective measure to control acute HDV. Intravenous drug use is no longer an efficient mode of HDV spread. Testing for IgM-anti HDV is a grey area requiring alert. Acute HDV in foreigners should be monitored in the years to come

    In-fan-cia : educar de 0 a 6 años : revista de la Associació de Mestres Rosa Sensat

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    Resumen basado en el de la publicaciónSe abordan los requerimientos necesarios para llevar a cabo actividades en la escuela de 0 a 3 años. En concreto, se exponen como puntos necesarios para llevar a cabo las actividades: regularidad y coherencia en la diversidad de las propuestas; respeto al tiempo personal; libertad de movimiento; materiales que habran vías de investigación.CataluñaBiblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5 - 3 Planta; 28014 Madrid; Tel. +34917748000; [email protected]

    A Day at Filastrocca Preschool, Pistoia, Italy: Meaning Making Through Literacy and Creative Experience

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    In this article,1 we explore how the library teacher of an Italian preschool with a special mission focused on books, stories, and the imagination uses group literacy activities as a context for encouraging shared meaning making through creative experiences. We take readers inside one day at the Italian Preschool, Filastrocca, providing detailed descriptions and analysis of interactions and activities. We suggest that elaborate extended dialogue among children and the teacher, promotion of empathy through opportunities to take others’ perspectives (including book characters’), and group engagement in shared and multi-faceted creativity are important characteristics related to meaning making in the context of relationships. Encouraging creative exploration and play across all domains of intelligence allows the children to develop their individual strengths into a product uniquely theirs

    Physiological Ligands ADP and P i

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