21 research outputs found
Changes in Amide-Linked and Ester Indole-3-Acetic Acid in Cotton Fruiting Forms during Their Development
Concentrations of Abscisic Acid and Indoleacetic Acid in Cotton Fruits and Their Abscission Zones in Relation to Fruit Retention
Changes in Abscisic Acid and Indoleacetic Acid before and after Anthesis Relative to Changes in Abscission Rates of Cotton Fruiting Forms
Purification and Measurement of Abscisic Acid and Indoleacetic Acid by High Performance Liquid Chromatography
Influence of Water Deficits on the Abscisic Acid and Indole-3-Acetic Acid Contents of Cotton Flower Buds and Flowers
Social Relationships and Mortality Risk: A Meta-analytic Review
In a meta-analysis, Julianne Holt-Lunstad and colleagues find that individuals' social relationships have as much influence on mortality risk as other well-established risk factors for mortality, such as smoking
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
We expanded GWAS discovery for type 2 diabetes (T2D) by combining data from 898,130 European-descent individuals (9% cases), after imputation to high-density reference panels. With these data, we (i) extend the inventory of T2D-risk variants (243 loci,135 newly implicated in T2D predisposition, comprising 403 distinct association signals); (ii) enrich discovery of lower-frequency risk alleles (80 index variants with minor allele frequency 2); (iii) substantially improve fine-mapping of causal variants (at 51 signals, one variant accounted for >80% posterior probability of association (PPA)); (iv) extend fine-mapping through integration of tissue-specific epigenomic information (islet regulatory annotations extend the number of variants with PPA >80% to 73); (v) highlight validated therapeutic targets (18 genes with associations attributable to coding variants); and (vi) demonstrate enhanced potential for clinical translation (genome-wide chip heritability explains 18% of T2D risk; individuals in the extremes of a T2D polygenic risk score differ more than ninefold in prevalence).Peer reviewe
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Irrigation and Nitrogen Effects on Plant Hormones, Boll Retention, and Growth of Fruiting Branches
An experiment was conducted in Phoenix in 1986 to determine effects of water and N deficits on ABA and IAA concentrations in young bolls and their abscission zones in relation to boll retention, and to determine the effects of N on growth of fruiting branches through the season. Water deficit decreased boll retention, decreased the concentration of free IAA in bolls and their abscission zones, and increased ABA in bolls and abscission zones. But, the concentration of ester IAA increased with water deficit (in contrast to free IAA). Because ester IAA resists degradation during stress, it may facilitate recovery when stress is relieved and some of it is converted to free IAA. N-deficiency symptoms were mild and did not appear early in the season. N had no effect on the ABA and IAA contents of bolls and their abscission zones, and had only a small effect on growth of fruiting branches. The N test is to be repeated in 1987 when N deficiency should be more severe
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Changes in Free and Bound Auxin with Development of Squares and Bolls in Relation to Shedding
Hormone analyses were conducted to determine why large squares seldom shed while young bolls do. Large squares contained five times as much free auxin as flowers, and they contained 16 times as much bound auxin. The high auxin content of large squares is probably a major reason that they almost never shed unless injured (for example, by insects). Free and bound auxin both decreased to very low levels at flowering and remained low for four days thereafter. This low concentration of auxin at, and just after, flowering is probably a major reason that bolls are likely to shed during the week after flowering. Both free and bound auxin increased rapidly between 7 and 9 days after flowering, possibly accounting for the decrease in boll shedding rate at this stage of development. Amide-linked IAA was the major form of auxin in squares, whereas ester IAA (presumably bound to sugars) was the major form of auxin in bolls