10 research outputs found
Finite element investigation of the effect of spina bifida on loading of the vertebral isthmus
- Author
- Publication venue
- Elsevier
- Publication date
- 01/04/2014
- Field of study
Background: Spondylolysis (SL) of the lower lumbar spine is frequently associated with spina bifida occulta (SBO). There has not been any study that has demonstrated biomechanical or genetic predispositions to explain the coexistence of these two pathologies. In axial rotation, the intact vertebral arch allows torsional load to be shared between the facet joints. In SBO, the load cannot be shared across the arch, theoretically increasing the mechanical demand of the vertebral isthmus during combined axial loading and rotation when compared to the normal state.
Purpose: To test the hypothesis that fatigue failure limits will be exceeded in the case of a bifid arch, but not in the intact case, when the segment is subjected to complex loading corresponding to normal sporting activities.
Study Design: Descriptive Laboratory Study.
Methods: Finite element models of natural and SBO (L4-S1) including ligaments were loaded axially to 1kN and were combined with axial rotation of 3°. Bilateral stresses, alternating stresses and shear fatigue failure on intact and SBO L5 isthmus were assessed and compared.
Results: Under 1kN axial load, the von Mises stresses observed in SBO and in the intact cases were very similar (differences <5MPa) having a maximum at the ventral end of the isthmus that decreases monotonically to the dorsal end. However, under 1kN axial load and rotation, the maximum von Mises stresses observed in the ipsilateral L5 isthmus in the SBO case (31MPa) was much higher than the intact case (24.2MPa) indicating a lack of load sharing across the vertebral arch in SBO. When assessing the equivalent alternating shear stress amplitude, this was found to be 22.6 MPa for the SBO case and 13.6 MPa for the intact case. From this it is estimated that shear fatigue failure will occur in less than 70,000 cycles, under repetitive axial load & rotation conditions in the SBO case, while for the intact case, fatigue failure will occur only over 10 million cycles.
Conclusion: SBO predisposes spondylolysis by generating increased stresses across the inferior isthmus of the inferior articular process, specifically in combined axial rotation and anteroposterior shear.
Clinical Relevance: Athletes with SBO who participate in sports that require repetitive lumbar rotation, hyperextension and/or axial loading are at a higher risk of developing spondylolysis compared to athletes with an intact spine
Effect of mechanical preconditioning on the electrical properties of knitted conductive textiles during cyclic loading
- Author
- Publication venue
- 'SAGE Publications'
- Publication date
- 10/01/2018
- Field of study
This paper presents, for the first time, the electrical response of knitted conductive fabrics to a considerable number of cycles of deformation in view of their use as wearable sensors. The changes in the electrical properties of four knitted conductive textiles, made of 20% stainless steel and 80% polyester fibers, were studied during unidirectional elongation in an Instron machine. Two tests sessions of 250 stretch–recovery cycles were conducted for each sample at two elongation rates (9.6 and 12 mm/s) and at three constant currents (1, 3 and 6 mA). The first session assessed the effects of an extended cyclic mechanical loading (preconditioning) on the electrical properties, especially on the electrical stabilization. The second session, which followed after a 5 minute interval under identical conditions, investigated whether the stabilization and repeatability of the electrical features were maintained after rest. The influence of current and elongation rate on the resistance measurements was also analyzed. In particular, the presence of a semiconducting behavior of the stainless steel fibers was proved by means of different test currents. Lastly, the article shows the time-dependence of the fabrics by means of hysteresis graphs and their non-linear behavior thanks to a time–frequency analysis. All knit patterns exhibited interesting changes in electrical properties as a result of mechanical preconditioning and extended use. For instance, the gauge factor, which indicates the sensitivity of the fabric sensor, varied considerably with the number of cycles, being up to 20 times smaller than that measured using low cycle number protocols
Neonatal head and torso vibration exposure during inter-hospital transfer
- Author
- Publication venue
- 'SAGE Publications'
- Publication date
- 13/10/2016
- Field of study
Inter-hospital transport of premature infants is increasingly common, given the centralisation of neonatal intensive care. However, it is known to be associated with anomalously increased morbidity, most notably brain injury, and with increased mortality from multifactorial causes. Surprisingly, there have been relatively few previous studies investigating the levels of mechanical shock and vibration hazard present during this vehicular transport pathway. Using a custom inertial datalogger, and analysis software, we quantify vibration and linear head acceleration. Mounting multiple inertial sensing units on the forehead and torso of neonatal patients and a preterm manikin, and on the chassis of transport incubators over the duration of inter-site transfers, we find that the resonant frequency of the mattress and harness system currently used to secure neonates inside incubators is ~9Hz. This couples to vehicle chassis vibration, increasing vibration exposure to the neonate. The vibration exposure per journey (A(8) using the ISO 2631 standard) was at least 20% of the action point value of current European Union regulations over all 12 neonatal transports studied, reaching 70% in two cases. Direct injury risk from linear head acceleration (HIC15) was negligible. Although the overall hazard was similar, vibration isolation differed substantially between sponge and air mattresses, with a manikin. Using a Global Positioning System datalogger alongside inertial sensors, vibration increased with vehicle speed only above 60 km/h. These preliminary findings suggest there is scope to engineer better systems for transferring sick infants, thus potentially improving their outcomes
The objectives for the mechanical evaluation of spinal instrumentation have changed
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The anatomy cookbook : a dissection guide with recipes
- Author
- Publication venue
- University of Nottingham
- Publication date
- 05/04/2010
- Field of study
The Anatomy Cookbook has been written to accompany an anatomy and physiology course for bioengineers who would otherwise have missed out on the opportunity to study real organ systems at first hand. It is not an alternative to a standard anatomy text, it acts more as a laboratory supplement. The fun bit is that your kitchen takes the place of the dissection room. Each recipe provides an insight into one or more organs, and all you need to do is go to the supermarket and be prepared to think about your food in a radically different way.
Pressure profilometry of the lumbosacral disk in dogs
- Author
- Adams MA
- Bray JP
- Bray JP
- Buckwalter JA
- Butterworth SJ
- Danielsson F
- Donal McNally
- Galante JO
- Hansen HJ
- Hendry NGC
- Holm S
- Ishihara H
- John F. Innes
- Marchand F
- McNally DS
- McNally DS
- McNally DS
- Merriam WF
- Nachemson A
- Ness MG
- Okushima H
- Osti OL
- Osti OL
- Palmer RH
- Palmer RH
- Richard A. S. Mitchell
- Smith JW
- Stairmand JW
- Takashi K
- Tanaka M
- Watt PR
- Wheeler SJ
- Wheeler SJ
- Publication venue
- 'American Veterinary Medical Association (AVMA)'
- Publication date
- Field of study
[The effect of low-dose hydrocortisone on requirement of norepinephrine and lactate clearance in patients with refractory septic shock].
- Author
- Abbey Ianthe
- Abdel Rehim Marwa
- Abdel Rehim Marwa
- Abdul Rahman A
- Abduljawwad Emad
- Abduljawwad Emad
- Abe Emuri
- Abe Ryuzo
- Aboab Jerome
- Aboab Jerome
- Acevedo Juan
- Acharya Anand
- Acquarolo Annamaria
- Acquarolo Annamaria
- Adamzik Michael
- Adamzik Michael
- Adembri Chiara
- Adrie Christophe
- Adrie Christophe
- Afessa Bekele
- Ainoda Yusuke
- Aiyar S
- Al Dabbagh Tarek
- Al Dabbagh Tarek
- Al Knawy Bandar A
- Al Knawy Bandar A
- Al-Abdulkareem Abdulmajeed
- Al-Abdulkareem Abdulmajeed
- Al-Abdulkareem Abdulmajeed
- Al-Abdulkareem Abdulmajeed
- Al-Arabi Rida
- Al-Dorzi Hasan M
- Al-Dorzi Hasan M
- Al-Muhamadi Ali
- Al-Naeeb Yasseen
- Al-Naeeb Yasseen
- Al-Shaer Mohammad
- Al-Shaer Mohammad
- Al-Tamimi Waleed
- Al-Tamimi Waleed
- Alaniz Cesar
- Alevizaki Maria
- Alevizaki Maria
- Alinejad Faranak
- AlJumah Abdulrahman
- AlJumah Abdulrahman
- AlJumah Abdulrahman
- AlJumah Abdulrahman
- AlJumah Abdulrahman
- AlJumah Abdulrahman
- Allolio Bruno
- AlNajjar Taghreed
- AlNajjar Taghreed
- Altintas M A
- Alvarez Jean-Claude Claude
- Alvarez Jean-Claude Claude
- Alvarez Jean-Claude Claude
- Amano Kosaku
- Amano Kosaku
- Amathieu Roland
- Amathieu Roland
- Amathieu Roland
- Amathieu Roland
- Ambriz-Plascencia Ana Rosa
- Ameen Abdelbadee
- Ameen Abdelbadee
- Amini Amir
- Amini Amir
- Amini Amir
- Amos Taryn
- Amour Julien
- Anderegg Brent A
- Anderegg Brent A
- Andersson Liane
- Andersson Liane
- Andrade Bertha Coelho
- Androulakis Ioannis P
- Aneja Rajesh
- Angus Derek C
- Angus Derek C
- Anjum Aisha
- Anjum Aisha
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annetta M
- Antonelli M
- Antonopoulou Anastasia N
- Antonopoulou Anastasia N
- Antonucci E
- Apollonatou Sofia
- Apollonatou Sofia
- Apostolidou Efterpi N
- Apostolidou Efterpi N
- Apostolou K
- Apostolou K
- Arabi Yaseen M
- Arabi Yaseen M
- Arabi Yaseen M
- Arabi Yaseen M
- Arabi Yaseen M
- Arabi Yaseen M
- Araujo Leonardo V
- Aravinthan Aloysious
- Aravinthan Aloysious
- Arbor Ann
- Arlt Wiebke
- Arlt Wiebke
- Armaganidis Apostolos
- Armaganidis Apostolos
- Armaganidis Apostolos
- Armaganidis Apostolos
- Aronowitz Paul
- Arriagada S Daniela
- Arroyo Vicente
- Arroyo Vicente
- Asahata Sayaka
- Asehnoune Karim
- Asehnoune Karim
- Asfar Pierre
- Asfar Pierre
- Ashby Deborah
- Ashby Deborah
- Ashby Deborah
- Ashby Deborah
- Ashby Deborah
- Ashby Deborah
- Atay Suleyman
- Atrash Jawad
- Atrash Jawad
- Aufort Sophie
- Aufort Sophie
- Augustatou Callirhoe
- Avidan Alexander
- Awasthi Shally
- Aya Hollmann D
- Aya Hollmann D
- Ayestaran Ignacio
- Ayestaran Ignacio
- Ayestaran Jose I
- Ayestaran Jose I
- Azoulay Elie
- Azoulay Elie
- Babajani Rafat
- Bagshaw Sean M
- Baharoon Salim
- Baharoon Salim
- Bailly-Salin Juliette
- Bailly-Salin Juliette
- Baker Aaron C
- Baker Aaron C
- Baker Aaron C
- Baker Aaron C
- Baker Aaron C
- Baker Tim
- Bander Joseph
- Banner Christina
- Barbeiro Hermes Vieira
- Barbosa Decio Sabbatini
- Barbosa Decio Sabbatini
- Barel Remy
- Barel Remy
- Barnett Adrian G
- Barnett Adrian G
- Barouk Jerome D
- Barton Michelle H
- Barton Michelle H
- Barton Michelle H
- Barton Michelle H
- Bauer Seth R
- Beale Richard J
- Beale Richard J
- Beale Richard J
- Beale Richard J
- Beale Richard J
- Behrend Ellen N
- Behrend Ellen N
- Bein Thomas
- Beishuizen Albertus
- Beishuizen Albertus
- Beishuizen Albertus
- Beishuizen Albertus
- Beishuizen Albertus
- Beishuizen Albertus
- Beishuizen Albertus
- Belkouchi Abdelkader
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellomo Rinaldo
- Bellomo Rinaldo
- Bellomo Rinaldo
- Bellomo Rinaldo
- Benbenishty Julie
- Bendel Stepani
- Benkabbou Amine
- Bennett Stephanie
- Bennett Stephanie
- Benson Sven
- Benson Sven
- Bercker Sven
- Bercker Sven
- Berger Mette M
- Berghall Elisabeth
- Berghall Elisabeth
- Berghaus R
- Berghaus R
- Bergt Stefan
- Bernardin Gilles
- Bernardin Gilles
- Bersten Andrew D
- Bertin-Maghit Marc
- Berton Christine
- Bertrand Jean Claude
- Best Al M
- Bhadada Sanjay
- Bhansali Anil
- Bhatia Vijaylaxmi
- Bhojwani K
- Bijkerk Ronald M
- Bilkovski Robert
- Bingel Ulrike
- Bingisser Roland
- Bingisser Roland
- Bissell Brittany D
- Bissell Brittany D
- Blanchard Anne
- Blanchard Anne
- Bloomfield Roxanna
- Blum Claudine A
- Boden L A
- Bogatsch Holger
- Bogatsch Holger
- Bohe Julien
- Bohe Julien
- Bokhari Faran
- Bollaert Pierre Edouard
- Bollaert Pierre Edouard
- Bollaert Pierre Edouard
- Bollaert Pierre Edouard
- Boney Charlotte M
- Boonen Eva
- Borba Evandro Lucas de
- Bornstein Stefan R
- Bosman Rob J
- Bosman Rob J
- Bosson Jean-Luc
- Botoula E
- Botoula E
- Boucly Catherine
- Boucly Catherine
- Boudou Philippe
- Bouloux Pierre-Marc
- Bouloux Pierre-Marc
- Boutron Carole M
- Bouzat Pierre
- Bozkurt Ahmet
- Bozkurt Ahmet
- Brett Stephen J
- Brett Stephen J
- Brett Stephen J
- Brett Stephen J
- Brett Stephen J
- Brett Stephen J
- Briassouli E
- Briassouli E
- Briassoulis G
- Briassoulis G
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Brierley Joe
- Brindley Peter G
- Brito Vinicius Nahime
- Brito Vinicius Nahime
- Brits Riette
- Brits Riette
- Britt L D
- Britt R C
- Brocas E
- Brockmeier Diane
- Broux Christophe
- Broux Christophe
- Brown Glen
- Brun-Buisson Christian
- Brun-Buisson Christian
- Brunkhorst Frank M
- Brunkhorst Frank M
- Brunkhorst Frank M
- Brunkhorst Frank M
- Brunkhorst Frank M
- Bruno Jeffrey Joseph
- Bruno Jeffrey Joseph
- Bruno Jeffrey Joseph
- Bruno Jeffrey Joseph
- Bubser Florian
- Buchele Gustavo Luiz
- Buchman Timothy G
- Buisson Christian Brun
- Buno Antonio
- Burkitt Jamie M
- Burroughs Andrew Kenneth
- Burroughs Andrew Kenneth
- Burroughs Andrew Kenneth
- Burroughs Andrew Kenneth
- Burry Lisa
- Burry Lisa
- Busch K H
- Butcher Stephen K
- Butschkau Antje
- Caillaud Denis
- Cakir E
- Calandra Thierry
- Calandra Thierry
- Caldera Maria V
- Caldwell Ellen
- Caldwell Ellen
- Calvano Steve E
- Calvano Steve E
- Candido-Vitto Cristina
- Caputo C
- Carcillo Joseph A
- Carcillo Joseph A
- Cariou Alain
- Cariou Alain
- Cariou Alain
- Cariou Alain
- Cariou Alain
- Carlier Robert
- Carlier Robert
- Carmean Amanda
- Carmean Amanda
- Carori Giampiero
- Carori Giampiero
- Carr Julie
- Carr Julie
- Carrilho Alexandre Jose Faria
- Carrilho Alexandre Jose Faria
- Carson Stephanie J
- Casanova Bonaventura
- Casanova Elena
- Casanova-Cardiel Luis Javier
- Cassar Charmaine
- Casserly Brian
- Casserly Brian
- Castanon-Gonzalez Jorge Alberto
- Castel Muriel
- Catravas John
- Cavaliere F
- Cazalis Marie-Angelique
- Cecconi Maurizio
- Cecconi Maurizio
- Cepkova Magda
- Cepkova Magda
- Cesari-Giordani Jean Francois
- Cesari-Giordani Jean Francois
- Cha Stephen S
- Chabre Olivier
- Chabre Olivier
- Chagnon Frederic
- Chagnon Frederic
- Chagnon Jean-Luc
- Chagnon Jean-Luc
- Chaney Whitney
- Chaney Whitney
- Chang Xiao
- Chang Xiao
- Chanques Gerald
- Chanques Gerald
- Chanques Gerald
- Chanques Gerald
- Chanques Gerald
- Chanson Anne Laure
- Chapman Marianne J
- Chapman Marianne J
- Chapman Marianne J
- Chapman Marianne J
- Chapman Marianne J
- Chappuis Philippe
- Charier David
- Charpentier Claire
- Charpentier Claire
- Chastre Jean
- Chastre Jean
- Chaudhury Prosanto
- Chaudry Irshad H
- Chen Huan-Wen
- Chen Luni
- Chen Ofer
- Chen Pang-Chi
- Chen Yung-Chang
- Chen Zhi
- Cherfan Antoine J
- Cherfan Antoine J
- Cherfan Antoine J
- Cherfan Antoine J
- Chevret Sylvie
- Chevret Sylvie
- Chevret Sylvie
- Chevret Sylvie
- Chevret Sylvie
- Chevret Sylvie
- Chew Victoria W
- Chew Victoria W
- Chew Victoria W
- Chew Victoria W
- Chew Victoria W
- Chia Wai-Kit
- Chiolero Rene
- Chiriac Stefan
- Chittawatanarat Kaweesak
- Chittawatanarat Kaweesak
- Cho Kiho
- Cho Kiho
- Cho Kiho
- Cho Kiho
- Cho Kiho
- Cho Kiho
- Chohnabayashi N
- Choi Hye-Sook
- Choi Hye-Sook
- Choi Seong-Soo
- Cholley Bernard P
- Choong Karen
- Choong Karen
- Chouinard Lucie
- Chouinard Lucie
- Chouker Alexander
- Chraibi Ahmed
- Chraibi Ahmed
- Christ-Crain Mirjam
- Christ-Crain Mirjam
- Christ-Crain Mirjam
- Christophoraki M
- Chronis Aris
- Chrousos George P
- Chung Jae Hoon
- Chung Man Pyo
- Chung Man Pyo
- Chung Man Pyo
- Chung Man Pyo
- Cisse Moussa
- Cisse Moussa
- Cisse Moussa
- Cisse Moussa
- Clark Adrian J L
- Clarke Iain J
- Clavieras Noemie
- Clavieras Noemie
- Clec'h Christophe
- Clec'h Christophe
- Clore John N
- Coates Thomas D
- Cohen Jeremy
- Cohen Jeremy
- Cohen Jeremy
- Cohen Jeremy
- Cohen Jeremy
- Cohen Jeremy
- Cohen Jeremy
- Cohen Jeremy
- Cohen Jeremy
- Cohen Jeremy
- Cohen Yves
- Cohen Yves
- Cole F J
- Coleman Jason
- Colin Gwenhael
- Colin Gwenhael
- Collier Andrew
- Collin S
- Collins J N
- Constantin Jean-Michel
- Constantin Jean-Michel
- Conti G
- Contrael Katlynd M
- Cook Deborah J
- Cooke Colin R
- Cooke Colin R
- Cooper D James
- Coopersmith Craig M
- Corbett Siobhan A
- Coret Francisco
- Coriat Pierre
- Cornell Tim
- Cortes-Puch Irene
- Cortes-Puch Irene
- Costigan Timothy M
- Costigan Timothy M
- Cotton Colleen
- Couppis Orestes
- Coursin Douglas B
- Coyle Susette M
- Coyle Susette M
- Craba A
- Crane Sean
- Creedon Jamie M Burkitt
- Criado Antonio
- Cruces R Pablo
- Crucian B E
- Cuthbertson Brian H
- Cuthbertson Brian H
- Cuthbertson Brian H
- Cuthbertson Brian H
- Cuthbertson Brian H
- Czepielewski Mauro Antonio
- Czepielewski Mauro Antonio
- Czepielewski Mauro Antonio
- Czepielewski Mauro Antonio
- Czeslick Elke
- D'honneur Gilles
- D'honneur Gilles
- D'Silva Celma
- da Cruz Neto Luiz Monteiro
- da Silva Fabiano Pinheiro
- Da Jiping
- Dabbagh Ousama
- Dabbagh Ousama
- Dalcin Diogo C
- Danner Robert L
- Danner Robert L
- Davidson Fraser
- Davis Alan
- De Backer Daniel
- De Gaudio A Raffaele
- de Jong Margriet Fleur Charlotte
- de Jong Margriet Fleur Charlotte
- de Jong Margriet Fleur Charlotte
- de Jong Margriet Fleur Charlotte
- de Jong Margriet Fleur Charlotte
- de Jong Margriet Fleur Charlotte
- de Sousa Santino Marcelo
- de Souza Heraldo Possolo
- de Wit Marjolein
- Deans Renae V
- Deans Renae V
- Decaen Allan
- Dee Brian M
- Dee Brian M
- Defranco Donald B
- Deger Orhan
- Dehne Marius G
- Deja Maria
- Dell-Kuster Salome
- Dellamonica Jean
- Dellamonica Jean
- Dellinger R Phillip
- Dellinger R Phillip
- Dellinger R Phillip
- Deshmukh C T
- Deutschman Clifford S
- Deutschman Clifford S
- Devaux Christian
- Deymann Andreas
- Dhar Rajat
- Diamantakis Argyris
- Dias Eduardo Pimentel
- Diaz R Franco
- Diconne Eric
- Diener K R
- Diener K R
- Dijstelbloem Hilde M
- Dimopoulou Ioanna
- Dimopoulou Ioanna
- Dimopoulou Ioanna
- Dimopoulou Ioanna
- Dimopoulou Ioanna
- Dimopoulou Ioanna
- Dimopoulou Ioanna
- Dimopoulou Ioanna
- Dimopoulou Ioanna
- Dimopoulou Ioanna
- Dimopoulou Ioanna
- Dizier Stephanie
- Dmello Dayton
- Dobb Geoffrey
- Dobb Geoffrey
- Doctor Allan
- Donal Erwan
- Donal Erwan
- Donal Erwan
- Donati Yannis
- Dondorp Arjen
- Dong Guijuan
- Dong Guijuan
- Donoso F Alejandro
- Dorin Richard I
- Dorin Richard I
- Dorin Richard I
- dos Santos Jose Wellington A
- Douglas Ivor S
- Douglas Ivor S
- Douka Evangelia
- Douka Evangelia
- Douka Evangelia
- Du Bin
- Ducrocq Nicolas
- Ducrocq Nicolas
- Duff John
- Dugas Marc-Andre
- Dumaine Robert
- Dumaine Robert
- Duncan Alan
- Dunser Martin W
- Dunser Martin W
- Dunser Martin W
- Dunser Martin W
- Dunser Martin W
- Dunser Martin W
- Dupuis Clement
- Durand Francois
- Durand Marie-Christine
- Dutta Pinaki
- Dyer Arron
- Edwards J
- Edwards J
- Edwards Ray
- Ehrhart-Bornstein Monika
- Eichacker Peter Q
- Eichacker Peter Q
- Eijsvogels Thijs M H
- Eikermann Matthias
- Einav Sharon
- Einav Sharon
- El Malki Hadj Omar
- Elatar Sayed L
- Elder Peter A
- Elhadd Tarik A
- Elsenbruch Sigrid
- Elsenbruch Sigrid
- Elsenbruch Sigrid
- Elsenbruch Sigrid
- Elsouri Naser
- Emonts Marieke
- Engel Christoph
- Engel Christoph
- Engeland William C
- Engelbrecht Elisa
- Engler Harald
- Engler Harald
- Engler Harald
- Engler Harald
- Engler Harald
- Erard Veronique
- Erdman Michael J
- Erdman Michael J
- Eriksson Mats B
- Eriksson Mats B
- Escorsell Angels
- Estrada-Y-Martin Rosa M
- Estrada-Y-Martin Rosa M
- Evans Barry
- Faivre V
- Fang Ji-Tseng
- Fartoukh Muriel
- Fartoukh Muriel
- Fatemi Mohammad Javad
- Faure Patrice
- Faure Patrice
- Fede Giuseppe
- Fede Giuseppe
- Fede Giuseppe
- Fede Giuseppe
- Feldman Jonathan
- Felipe Vanessa
- Felmet Kathryn
- Ferguson D C
- Ferguson D C
- Fernandez Javier
- Fernandez Javier
- Fernandez-Balsells Mercedes
- Fernandez-de-Castillo Ana G
- Fernandez-de-Castillo Ana G
- Ferreira Jason A
- Ferreira Jason A
- Festic Emir
- Festti Josiane
- Festti Josiane
- Festti Luciana
- Festti Luciana
- Fiaccadori E
- Fick Wilhelmina F
- Fiedler Fritz
- Finfer Simon
- Finfer Simon
- Finkielman Javier D
- Fiorese Bertilla
- Fiorese Bertilla
- Fisher Gene
- Fleseriu Maria
- Flores-Barrientos Oscar Israel
- Forceville Xavier
- Forceville Xavier
- Forst Helmuth
- Forsting Michael
- Forsting Michael
- Fortenberry James D
- Fortenberry James D
- Fortenberry James D
- Fortenberry James D
- Fouassier Marc
- Fouda Ossama M
- Fougerou Claire
- Frankel Lorry
- Fraser Gilles L
- Fraser John F Jonathan D
- Fraser John F Jonathan D
- Fraser John F Jonathan D
- Frasko R
- Fratto Melanie A
- Frazier Gregory J
- Frazier Gregory J
- Freche Annie
- Freche Annie
- Freichet M
- Freichet M
- Freire Amado X
- Freivogel Klaus
- Freivogel Klaus
- Freivogel Klaus
- French C
- Frere-Meunier Delphine
- Frey Ulrich H
- Frey Ulrich H
- Friedman Gilberto
- Friedman Gilberto
- Friedman Gilberto
- Friedman Gilberto
- Fries Michael
- Fritz H
- Frontera Guillem
- Frostell Claes
- Frostell Claes
- Fuchs Paul Ch
- Fuchs Paul Ch
- Fujita Motoki
- Fujita Motoki
- Fujita Takahiro
- Fuller Brian M
- Gaillard Jean-Luis
- Gallix Benoit
- Gallix Benoit
- Gallix Benoit
- Gallo-Payet Nicole
- Gallo-Payet Nicole
- Gan Quan
- Gan Quan
- Ganbat Tsenddorj
- Garcia Audwin J
- Garcia Laura
- Garcovich Matteo
- Garcovich Matteo
- Garfield Mark
- Garfield Mark
- Gaspari R
- Geffner Mitchell E
- Gellert M
- Gentilhomme Anne
- Gentilhomme Anne
- Genty Celine
- Gerlach Herwig
- Gerlach Herwig
- Gerlach Herwig
- Gerlach Herwig
- Gerlach Herwig
- Gerlach Herwig
- Germani Giacomo
- Germani Giacomo
- Gessner Sophia
- Gessner Sophia
- Geurts-Moespot Anneke
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- Giannoni Eric
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- Giguere Steeve
- Gilfoyle Elaine
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- Golden Emmel
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- Grander Wilhelm
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- Grion Cintia Magalhaes Carvalho
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- Hamitouche Noureddine
- Hammer Fabian
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- Harward Meg
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- Hazelzet Jan A
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- Imamoglu Mustafa
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- Ioakeimidou Aikaterini
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- Rabuazzo Agata Maria
- Radermacher Peter
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- Raja Sabudin Raja Zahratul Azma
- Rajbhandari Dorrilyn
- Rajbhandari Dorrilyn
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- Rajput Rajesh
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- Ramos-Gallardo Guillermo
- Ramsay Graham
- Ramsay Graham
- Ramsay Tim
- Rankin W
- Rankin W
- Ratanarat Ranistha
- Ratanarat Ranistha
- Rathia S K
- Raurich Joan Maria
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- Reade Michael C
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- Rebernik Laura
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- Rech Megan A
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- Reinhart Konrad
- Reinhart Konrad
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- Reinhart Konrad
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- Resener Kerstin
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- Retsas Theodoros A
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- Reverdy F
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- Rex Christopher
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- Richardson Paul
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- Rocco J R
- Roch Antoine
- Rochwerg Bram
- Rockliff Sue
- Roderigo Till
- Rodriguez Agustin
- Rodriguez Carlos J
- Roesner Jan P
- Roger Thierry
- Roquilly Antoine
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- Rosenberger Christina
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- Roth-Kleiner Matthias
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- Rubenfeld Gordon D
- Rubenfeld Gordon D
- Rubenfeld Gordon D
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- Rungruanghiranya Suthat
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- Ruokonen Esko
- Ruokonen Esko
- Ruokonen Esko
- Ruokonen Esko
- Rushing G D
- Russel J A
- Russell James A
- Saarela Timo
- Saberi Mohsen
- Sablotzki Armin
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- Sadahiro Tomohito
- Saharee A A
- Saladino Richard A
- Salgado D R
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- Santre Charles
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- Sarquis Marta Maria S
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- Sarret Philippe
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- Satoh Mamoru
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- Scalea Thomas M
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- Schafer Simon T
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- Schmittinger Christian A
- Schmittinger Christian A
- Schmittinger Christian A
- Schnitzler Eduardo
- Schoonhoven Lisette
- Schrader Ronald M
- Schrader Ronald M
- Schroder Daniel C H
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- Schuerholz Tobias
- Schuerholz Tobias
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- Schultz Marcus J
- Schutz Stefanie
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- Sen Nagamani
- Sennoun N
- Sevransky Jonathan E
- Sevransky Jonathan E
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- Shaaban Yasser Hassan
- Shafarin M S
- Shanley Tom
- Sharma Navneet
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- Sharshar Tarek
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- Sharshar Tarek
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- Shekar Kiran
- Sherlock C E
- Sherwin Robert Leigh
- Shibata Audrey R Ogawa
- Shigeta Osamu
- Shih Chung-Hung
- Shih Kuang-Chung
- Shim Tae Sun
- Shim Tae Sun
- Shinozaki Koichiro
- Shiratsuka H
- Shmuelevitz Lev
- Shmuelevitz Lev
- Shorten Paul R
- Siami Shidasp
- Siami Shidasp
- Siami Shidasp
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- Siffert Winfried
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- Singer Mervyn
- Singer Mervyn
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- Singh S N
- Singhi Sunit
- Sirola Joonas
- Sirola Joonas
- Sjolin Jan
- Skippen Peter
- Slack Sally
- Sleight Kirsten
- Slovis N M
- Slovis N M
- Slovis N M
- Smeekens Sanne P
- Smeets R
- Smielewski Peter
- Smith Dominic
- Smith Melissa Lassig
- Smith Melissa Lassig
- Smitz Johan
- Smitz Johan
- Smotherman Carmen
- Smotherman Carmen
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- Soderberg Ewa
- Sogawa Kazuyuki
- Sollevi Alf
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- Solomkin Joseph S
- Solomon Steven B
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- Soop Anne L
- Soop Anne L
- Sotiropoulou Ch
- Souweine Bertrand
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- Spadaro Luisa
- Spadaro Luisa
- Spadaro Luisa
- Spies Claudia D
- Spijkstra Jan-Jaap
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- Spranger Joachim
- Spreitzer Ingo
- Sprung Charles L
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- Spuler Simone
- Srivijitkamol Apiradee
- Srivijitkamol Apiradee
- Stanciu Carol
- Stein Deborah M Dan J
- Stein Deborah M Dan J
- Steinau H-U
- Steiner Luzius A
- Steingrub Jay S
- Steingrub Jay S
- Steinmann Jorg
- Steinmann Jorg
- Steinstrasser L
- Stellini Roberto
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- Sterk Ethan
- Sterk Ethan
- Stern Naftali
- Stevens N E
- Stevens N E
- Stewart Paul M
- Stiefelhagen Peter
- Stockwell Jana A
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- Stoffels Monique
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- Stolz Daiana
- Stolz Daiana
- Stone Angela
- Storms Michelle M
- Stotz Martin
- Stotz Martin
- Stowe R P
- Strack van Schijndel Rob J M
- Strauss Julian
- Strebel Stephan P
- Stromeyer Hans G
- Sturgess David J
- Sturgess David J
- Su Deng-Huang
- Suh Gee Young
- Suh Gee Young
- Suh Gee Young
- Suh Gee Young
- Sun Jiaxiao Junfeng
- Sun Jiaxiao Junfeng
- Sun Jiaxiao Junfeng
- Sun Jiaxiao Junfeng
- Suter Fredy
- Suter Fredy
- Sweeney Daniel A
- Sweeney Daniel A
- Sweeney Lori B
- Sweep Fred C G J
- Tabah Alexis
- Tabah Alexis
- Taccone F S
- Tajiri Takashi
- Takahashi O
- Takano Kazue
- Takano Kazue
- Takata Katsuyoshi
- Takata Katsuyoshi
- Takeda Shinhiro
- Tamim Hani M
- Tamim Hani M
- Tamim Hani M
- Tamim Hani M
- Tamim Hani M
- Tamim Hani M
- Tamimi Waleed
- Tamimi Waleed
- Tamimi Waleed
- Tamimi Waleed
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- Tamm Michael
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- Tan Terrence
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- Tassin C
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- Tesniere Antoine
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- Thalassinos N C
- Theodorakopoulou Maria
- Theodorakopoulou Maria
- Theodorakopoulou Maria
- Thiel Manfred
- Thierry S
- Thirunavukkarasu Neeraja
- Thirunavukkarasu Neeraja
- Thomas Michael
- Thomas Michael
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- Thomas Zachariah
- Thomasy Sara M
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- Timsit Jean-Francois Francois
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- Timsit Jean-Francois Francois
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- Tol Maneesha M
- Tol Maneesha M
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- Torpy David J
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- Torpy David J
- Torpy David J
- Torpy David J
- Torpy David J
- Torpy David J
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- Townsend Sean R
- Townsend Sean R
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- Trips Evelyn
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- Tsagarakis Stylianos
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- Tsekouras A
- Tseng Jo-Chi
- Tseng Jo-Chi
- Tsirantonaki M
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- Tsochatzis Emmanuel
- Tsochatzis Emmanuel
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- Tsuruta Ryoske
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- Tung Kelly
- Tung Kelly
- Tung Kelly
- Tung Kelly
- Tung Kelly
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- Um Sang-Won
- Umberger Reba
- Ungerer Jacobus P J
- Ungerer Jacobus P J
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- Urban Frank K 3rd
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- Uusaro Ari
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- Vallet Benoit
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- Valoor Harsha T
- van Alfen Nens
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- van Stijn Ilse
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- van Zanten Mark
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- Vardas K
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- Vassiliadi Dimitra Argyro
- Vassiliadi Dimitra Argyro
- Vassiliadi Dimitra Argyro
- Vassiliadi Dimitra Argyro
- Vassiliadi Dimitra Argyro
- Vassiliadi Dimitra Argyro
- Vassiliagkou Spyridoula D
- Vassiliagkou Spyridoula D
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- Venkatesh Balasubramanian
- Venkatesh Balasubramanian
- Venkatesh Balasubramanian
- Venkatesh Balasubramanian
- Venkatesh Balasubramanian
- Venkatesh Balasubramanian
- Venkatesh Balasubramanian
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- Vermes Istvan
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- Vicaut Eric
- Villa F
- Villagran Maria J
- Vincent Jean Louis J-L Jean-Louis L
- Vincent Jean Louis J-L Jean-Louis L
- Vincent Jean Louis J-L Jean-Louis L
- Vincent Jean Louis J-L Jean-Louis L
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- Vincent Jean Louis J-L Jean-Louis L
- Vincent Jean Louis J-L Jean-Louis L
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- Wagner Nana-Maria
- Walker Mark L
- Walley Keith R
- Wang Chun-Hua Changsong
- Wang Chun-Hua Changsong
- Wang Chun-Hua Changsong
- Wang Ling
- Wang Ling
- Wang Miaomiao
- Wang Miaomiao
- Wang Ti-Hao
- Ward Gregory
- Ward Gregory
- Watson Dale
- Webb Ian
- Webb Steven A R
- Webb Steven A R
- Webb Steven A R
- Webb Steven A R
- Webb Steven A R
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- Wegner Alexander
- Wegner Alexander
- Wegner Alexander
- Weiler Norbert
- Weiler Norbert
- Weingarten Jacki
- Weireter L J
- Weis Florian
- Weis Florian
- Weiss Manfred
- Weiss Yoram G
- Weiss Yoram G
- Weiss Yoram G
- Weiss Yoram G
- Weiss Yoram G
- Weiss Yoram G
- Weiss Yoram G
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- Wensley David
- Wenzel Volker
- Werdan K
- Wernecke Klaus D
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- Westendorf Astrid M
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- Westermeyer Hans D
- Westphal Martin
- Wetterslev J
- Weyland Andreas
- Weyland Andreas
- Whitley Elizabeth M
- Whitley Elizabeth M
- Wiaterek Gregory K
- Williams Mark D
- Williams Mark D
- Winkler Margaret
- Wirtz Stefan P
- Wirtz Stefan P
- Witchel Selma F
- Wolf Anna M
- Wolf Irene M
- Wolf Michel
- Wolf Michel
- Wolf Oliver T
- Wolter Timm
- Won Justin Ging-Shing
- Wong Chieh-Lee
- Wong Hector R
- Wong Hector R
- Wong Hector R
- Wood John C
- Wouters Pieter J
- Woyciechowsky Tiago G
- Wright Robert
- Wu Cheng-Shyong
- Wu Huang-Pin
- Wu Huang-Pin
- Wu Ling-Yi
- Wu Ta-Wei
- Wynn James L
- Xirouchakis Elias
- Xu Jun
- Xu Mujuan
- Xu Mujuan
- Yamamoto Masakazu
- Yamamoto Masakazu
- Yamashita Kiyohiko
- Yang Chunli
- Yang Chunli
- Yee Kristen S
- Yee Kristen S
- Yeh Timothy
- Yu Chung-Chieh
- Yu Chung-Chieh
- Yu Jihion
- Yu Teng-Jen
- Yu Teng-Jen
- Yu Xuezhong
- Yu Yuan-Bin
- Yu Zhui
- Yu Zhui
- Yuan Ying
- Zabalza Michel
- Zakynthinos Spyros
- Zakynthinos Spyros
- Zaloga Gary
- Zaman Muhammad
- Zampieri Fernando Godinho
- Zamri-Saad M
- Zandstra Durk F
- Zandstra Durk F
- Zaritsky Arno
- Zeni Fabrice
- Zervou Maria
- Zhang Fengmin
- Zhang Fengmin
- Zhang Haibo
- Zhang Haibo
- Zhang Qian
- Zhang Qian
- Zhang Yang
- Zhang Yang
- Zhang Zhong
- Zhang Zhong
- Zhao Xin
- Zhao Xin
- Zheng Juanjuan
- Zheng Juanjuan
- Zheng Liangliang
- Zhou Qing
- Zhou Qing
- Zhu Huadong
- Ziegenfuss Marc
- Ziegenfuss Marc
- Zijlstra J G
- Zimmerman Jerry J
- Zimmerman Jerry J
- Zuckerberg Aaron
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/10/2007
- Field of study
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdag Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
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- NA N.A.
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- Nsengiyumva Carlos
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- Nyangoh Timoh Krystel
- O'Connor Donal B
- O'Neill Maeve
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- Ogundoyin Olakayode
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- Perivoliotis Konstantinos
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- Sayed Mohamed Marwa
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- Shah Reena
- Shaheen Ahmad
- Shaheen Nureddin
- Shahien Fatma
- Shahzad Noman
- Shaker Nancy
- Shakhmatov Dmitry
- Shalaby Hind I.
- Shalaby Mostafa
- Sharif Randa
- Sharma Parivrudh
- Shaw Catherine A
- Shaw Mike
- Shawqi Muhammad
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- Wong Jane J
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- Yaghi Yasmine
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- Yakushkina Al'ona
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- Yang P Zichu
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- Yanni Fady
- Yates Charlotte
- Ye Geoffrey
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- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
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- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Šatkauskas Mindaugas
- Škimelyte Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdağ Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
- Alvi Abdul
- Alwaheidi Malak
- Alwali Abdallah
- Alwerfally AbdulMawlay
- Alwhaidi Noor
- Alyafi Amr
- Alzabti Fatima
- Alzahaf Ahmed
- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
- Amjad Talal
- Amorim Edgar
- Amro Adham
- Anandan Premkumar
- Anas khalifa Rawda
- Anastasio Lorenzo
- Andersson Yvette
- Andreotti Dario
- Andrew David
- André Benoît
- Ang Sue Ean
- Angel Miguel
- Anggita Gultom Phebe
- Annapureddy Naga
- Anokhin Evgeny
- Ansaloni Luca
- Ansarei Dhirar
- Ansari Abdul Basit
- Antaky Marco
- Anthony Natasha
- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
- Anyanwu Mercy Chinemerem
- Anyomih Theophilus Teddy Kojo
- Appukuttan Akhila
- Aquilino Fabrizio
- Archibald Jess
- Arciénega Yañez María del pilar
- Argentou Maria-Ioanna
- Argudo Nuria
- Argyriou Eleftherios Orestis
- Arias Madrid Natalia
- Aribi Sarra
- Arifin Ghafur Rasyid
- Arizpe Daniel
- Arnaud Alexis P
- Arora Bharti
- Arora Deeksha
- Arowolo Olukayode
- Arrangoiz Rodrigo
- Arslan Ekin
- Artigau Eva
- Ashfaq Ahsan
- Ashour Dina
- Ashour Firas
- Ashoushan Hana
- Ashraf Ahmed
- Ashraf Alaa
- Asif Ashar
- Asnel Dorisme
- Asok Anjitha
- Assa Rawan
- Assalhi Mohamed
- Asta Martina
- Asti Emanuele Luigi Giuseppe
- Atakul Onur
- Atallah Khalid
- Atanasov Boyko
- Atawneh Mohammad
- Athamneh Sarah
- Ather Muaaz
- Athisayaraj Thomas
- Atkociunas Aivaras
- Attia Mohamed
- Au Angela
- Awad Israa
- Awadallah Haneen
- Awaji Kholoud
- Awesat Eman
- Awolowo Ajibola
- Ayandipo Omobolaji
- Ayash Mohammad
- Ayau Fernanda
- Ayesh Kholoud
- Ayman El-sawy Esraa
- Ayoub Rami
- Aytac Erman
- Ayub Bushra
- Ayub Saima
- Ayyad Rawan
- Azevedo José
- Azodo Ijeoma
- Azzubia Joma
- B L Ashika
- Ba Mouhamadou Bachir
- Babaa Basheer
- Babirye Lilian
- Bacic Ivan
- Badr Esraa Tarek
- Badr Helmy
- Badran Abdul
- Badwe Rajendra
- Bafford Andrea Chao M.D.
- Baggaley Caitlin
- Bahroun Sumayyah Ghayth
- Baiao José Miguel
- Baiocchi Daniella
- Bairos Menezes Maria
- Baiu Ioana
- Bajilan Mohammad
- Bajomo Oreoluwa
- Bake Jacques
- Baki Bahadir Emre
- Bakoleas Panagiotis
- Balaawi Reem
- Balalis Dimitrios
- Balata Mohamed
- Balkarov Artem
- Ballouhey Quentin
- Balogun Olanrewaju
- Baloyiannis Ioannis
- Baltaci Ege
- Bamaca Ixcajoc Elvis Benjamin
- Banaz Tuba
- Banda Bitiel
- Banglani Muntaha
- Bani Hani Farah
- Bani hani Mohammad
- Bani hani Zeina
- Baniowda Muath
- Banks Alexander
- Bannister Sharon
- Baranyai Zsolt
- Barati Nastaran
- Barbosa Camacho Francisco José
- Barbosa José
- Bardos David
- Barendegere Venerand
- Barghuthi Lutfi
- Barhoush Ola
- Barnes Nicole
- Baronio Gianluca
- Barreda Zelaya Lilian Elizabeth
- Barrera López Francisco Javier
- Barsic Neven
- Barter Charlotte
- Bartosiak Katarzyna
- Basarab Maksym
- Basso Stefano Maria Massimiliano.
- Bastiaenen Vivian
- Batashki Ilia
- Bath Michael
- Beattie Miriam
- Bedada Alemayehu Ginbo
- Belais Fanny
- Belal qadomi Asef
- Belev Nikolay
- Belli Andrea
- Beltrán de Heredia Juan
- Belvedere Angela
- Ben Dallah Najah
- Ben Saoud Abdulsalam Ali
- Bengur Fuat Baris
- Benkabbou Amine
- Benke Marton
- Benyaiche Chaymae
- Bergeat Damien
- Bernstein Mitchell
- Beshtawi Doha
- Besli Sevval
- Beuran Mircea
- Bhandare Manish
- Bhangu Aneel
- Bhatti Muhammad Iqbal
- Bianchini Stefania
- Bianco Francesco
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- Forero-Torres Alexander
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- Ghosh Dhruv
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- Haji Reema
- Hajjaj Ahmed N K
- Hall Timothy
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- Tashkandi Hanaa
- Tashkandi Wail
- Tatar Ozan Can
- Tavlas Panagiotis
- Tawalbeh Ra'fat
- Tawalbeh Tamara
- Tayar Serkan
- Tayler Viki
- Teasdale Ella
- Teh Jen
- Tejeda Garrido Jorge Carlos Guillermo
- Tennakoon Athula
- Tepe Mustafa Deniz
- Teppo Sandra
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- Tereshchenko Maksym
- Tew Yong Yong
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- Thalgaspitiya Sujeewa Priyantha Bandara
- Tharanath Kavya
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- Theodoropoulos Charalampos
- Theodorou Dimitrios
- Theodosopoulos Theodosios
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- Trujillo Díaz Jeancarlos
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- van Berge Henegouwen Mark I.
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- Warwicker Sean
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- Watts Daniel
- Weiser Thomas G
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- Wilson Michael
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- Wogensen Fredrik
- Wondoh Paul M.
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- Wong Tsz Lun Ernest
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- Yoong Andrel
- Yorke Joseph
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- You Lucia
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- Yu Kristin
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- Yusuf Baasil
- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Čepuliené Daiva
- Şahin Can
- Šatkauskas Mindaugas
- Škimelytè Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/2022
- Field of study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research