46 research outputs found
Exposure to environmental microbiota explains persistent abdominal pain and irritable bowel syndrome after a major flood
Collection of non-meconium stool on fecal occult blood cards is an effective method for fecal microbiota studies in infants
Knowledge gained from a 31-h power outage in Berlin Köpenick—medical problems and challenges
Common methods for fecal sample storage in field studies yield consistent signatures of individual identity in microbiome sequencing data
Design and Synthesis of 2-Methyl-2-{4-[2-(5-methyl-2-aryloxazol- 4-yl)ethoxy]phenoxy}propionic Acids: A New Class of Dual PPARα/γ Agonists
Involvement of Phosphorylase Kinase Inhibition in the Effect of Resorcinol and Proglycosyn on Glycogen Metabolism in the Liver
Molecular Modelling Studies of 1,4-Diaryl-2-Mercaptoimidazole Derivatives for Antimicrobial Potency
Coffee, tea, caffeine intake, and the risk of cancer in the PLCO cohort
Background: The association between coffee intake, tea intake and cancer has been extensively studied, but associations are not established for many cancers. Previous studies are not consistent on whether caffeine may be the source of possible associations between coffee and cancer risk. Methods: In the Prostate, Lung, Colorectal, and Ovarian cancer screening trial, of the 97 334 eligible individuals, 10 399 developed cancer. Cancers included were 145 head and neck, 99 oesophageal, 136 stomach, 1137 lung, 1703 breast, 257 endometrial, 162 ovarian, 3037 prostate, 318 kidney, 398 bladder, 103 gliomas, and 106 thyroid. Results: Mean coffee intake was higher in lower education groups, among current smokers, among heavier and longer duration smokers, and among heavier alcohol drinkers. Coffee intake was not associated with the risk of all cancers combined (RR=1.00, 95% confidence interval (CI)=0.96-1.05), whereas tea drinking was associated with a decreased risk of cancer overall (RR=0.95, 95% CI=0.94-0.96 for 1+ cups per day vs <1 cup per day). For endometrial cancer, a decreased risk was observed for coffee intake (RR=0.69, 95% CI=0,52-0.91 for 652 cups per day). Caffeine intake was not associated with cancer risk in a dose-response manner. Conclusions: We observed a decreased risk of endometrial cancer for coffee intake, and a decreased risk of cancer overall with tea intake