Gold Nanoparticles on Yttrium Modified Titania: Support Properties and Catalytic Activity

A series of titanium oxide catalysts modified with yttrium has been prepared by sol¿gel method and their structural properties have been studied. The incorporation of yttrium in the titania lattice favors the formation of oxygen vacancies while at low Y loadings the anatase structure is preserved. The catalytic activity of these solids for CO oxidation is found to be significantly dependent on their physical properties. In particular the amount of dopant controls the number of surface oxygen vacancies created as well as the gold particle size, which directly affects the catalytic activity. Also, a linear relationship between the catalytic activity and the band gap values, which depend on the Y loading, is observed. Density functional theory based calculations show that Y atoms are incorporated at the TiO2 surface at substitutional positions only, while the preferred oxygen vacancies arise by removing the bridge surface oxygen atoms. These O-vacancies are the preferential adsorption sites for Au atoms and nanoparticles, acting as nucleation centers that favor the dispersion of the catalyst active phase over the support surface. In agreement with experiment, Y doping is found to decrease the band gap of the support due to a destabilization of the valence band of the oxide.Ministerio de Ciencia e Innovación ENE2009-14522-C05-01, MAT2008-04918, CSD-00023Junta de Andalucía P08-FQM-0366

Hernia de Spiegel. A propósito de un caso

Introducción: La Hernia de Spiegel es un raro defecto de la pared abdominal generalmente mal diagnosticado. En la experiencia de los cirujanos, las hernias de la pared abdominal constituyen una enfermedad cuyo diagnóstico es esencialmente clínico. Sin embargo, la Hernia de Spiegel por su infrecuente presentación (0,1-2%) pasa fácilmente inadvertida. Objetivo: Informar un tipo de hernia poco frecuente.Presentación del caso: En este artículo presentamos un paciente masculino de 51 años, quien fuera hospitalizado para tratamiento quirúrgico con diagnóstico de hernia inguinal derecha directa y en el acto operatorio se le diagnosticó Hernia de Spiegel. Conclusiones: Por las dificultades diagnósticas que presenta esta enfermedad es importante realizar una correcta anamnesis y examen físico, sin olvidar estudios de imagen. El tratamiento definitivo de la Hernia de Spiegel es el quirúrgico. Palabras clave: Hernia de Spiegel, Cirugía, Hernia abdominal. Normal 0 21 false false false ES X-NONE X-NONE </p

Arquitectura de software para el desarrollo de videojuegos sobre el motor de juego Unity 3D

En los últimos años la arquitectura de software se ha consolidado como una disciplina que intenta contrarrestar los efectos negativos que pueden surgir durante el desarrollo de un producto informático, ocupando un rol significativo en la estrategia de negocio de una organización que basa sus operaciones en el software, volviéndose necesaria para todo tipo de desarrollo, incluyendo los videojuegos. La presente investigación tiene como objetivo desarrollar una arquitectura de software para videojuegos desarrollados sobre el motor de juego Unity 3D, que permita organizar y estructurar sus características funcionales básicas. A partir del estudio de arquitecturas usadas en videojuegos se agruparon las clases candidatas de la solución propuesta, identificándose los paquetes principales, dependencias entre ellos, patrones de diseño y buenas prácticas empleadas, concretando una arquitectura de software basada en la integración de los tipos de arquitectura: en capas y basada en componentes. Se desarrolla un prototipo funcional de un videojuego del género plataformas, empleando para describirlo elementos del diseño de videojuegos, especificación de mecanismos y las vistas propuestas por Robert Nord: conceptual, de módulos, de código y de implementación. La arquitectura propuesta fue validada a través de las técnicas de evaluación basadas en prototipos, en escenarios y en conjunto con la aplicación del método de Análisis de Acuerdos de Arquitectura de Software. Con la aplicación de esta técnica se identificaron los riesgos presentes en la arquitectura propuesta, teniendo en cuenta el comportamiento de atributos de calidad sobre la solución, según el modelo ISO/IEC 25010

Dynamics and numerical simulations to predict empirical antibiotic treatment of multi-resistant Pseudomonas aeruginosa infection

This work discloses an epidemiological mathematical model to predict an empirical treatment for dogs infected by Pseudomonas aeruginosa. This dangerous pathogen is one of the leading causes of multi-resistant infections and can be transmitted from dogs to humans. Numerical simulations and appropriated codes were developed using Matlab software to gather information concerning long-time dynamics of the susceptible, infected and recovered individuals. All data compiled from the mathematical model was used to provide an appropriated antibiotic sensitivity panel for this specific infection. In this study, several variables have been included in this model to predict which treatment should be prescribed in emergency cases, when there is no time to perform an antibiogram or the cost of it could not be assumed. In particular, we highlight the use of this model aiming to become part of the convenient toolbox of Public Health research and decision-making in the design of the mitigation strategy of bacterial pathogens

Systematic Review of Patient-Reported Outcome Measures for Patients with Exercise-Induced Leg Pain

Background and Objectives: To determine the most commonly used patient-reported outcome measures (PROMs) in exercise-induced leg pain (EILP) and to identify specific PROMs for EILP in order to evaluate their psychometric properties and methodological quality. Materials and Methods: A strategic search was performed in different databases to identify and extract the characteristics of studies based on the use of PROMs in patients with EILP. Specific PROMs were evaluated according to the Terwee et al. and COSMIN criteria. Results: Fifty-six studies were included in the review. The Medial Tibial Stress Syndrome Score (MTSSS), Lower Extremity Functional Scale (LEFS) and Exercise-Induced Leg Pain Questionnaire (EILP-Q) were identified as specific PROMs for EILP. The Visual Analog Scale (VAS) was the most widely used instrument in the assessment of EILP. The methodological quality assessment showed six positive values for the LEFS, four for the MTSSS and three for the EILP-Q for the eight psychometric properties analyzed according to the COSMIN criteria. The evaluation of the nine psychometric properties according to Terwee showed five positive values for the LEFS and MTSSS, and three for the EILP-Q. Conclusions: The overall methodological quality of the PROMs used was low. The VAS was the most widely used instrument in the assessment of EILP, and the LEFS was the highest quality PROM available for EILP, followed by the MTSSS and EILP-Q, respectively.Castillo-Domínguez A, García-Romero JC, Alvero-Cruz JR, Ponce-García T, Benítez-Porres J, Páez-Moguer J. Systematic Review of Patient-Reported Outcome Measures for Patients with Exercise-Induced Leg Pain. Medicina. 2022; 58(7):841. https://doi.org/10.3390/medicina5807084