312 research outputs found

    Validity of a contact mat and accelerometric system to assess countermovement jump from flight time

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    Countermovement jump (CMJ) height is an important parameter in physical performance. This study compared CMJ height measured using ChronoJump contact mat (CJ) and Myotest accelerometer (MT) systems with a force platform (FP). Thirty recreationally active adults (32.1 ± 10.4 years, 75.9 ± 12.0 kg, 173.2 ± 6.3 cm) completed a CMJ protocol where height was simultaneously recorded using the three systems. CJ and MT measures were strongly and significant correlated (r = 0.65, 0.66, respectively; p  0.05), yet MT-derived measures were significantly different from those obtained using the FP (p < 0.05). Systematic bias was observed between FP and the CJ and between FP and MT. This study demonstrates the validity of CJ and MT systems for the assessment of CMJ height. Systematic bias and between-device differences in measurement should be considered when interpreting and comparing data from these devices

    Comparison of Forward, Backward, and Conventional Training in the Learning of a List of CVC Trigrams

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    Ss were instructed to learn a list of 10 CVC trigrams by either the conventional serial anticipation method, backward conditioning or forward conditioning. The F ratio failed to show a significant difference between the three experimental groups. The results contradict previous results which shown that forward training is more efficient than the other two methods

    Monitoring Driver Drowsiness and Stress in a Driving Simulator

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    Driver drowsiness, compounded by the high workloads and stress of the ever-increasing complexity of car and traffic environments, is a major cause of severe accidents. The objective of the project described in this paper is to develop reproducible and flexible methods for studying the relationships between physiological driver states and human-factor issues in a driving environment. For reasons of safety and reproducibility, a laboratory-based driving simulator is being used for the project experiments. Initial experiments were conducted with a cohort of about 60 healthy male subjects aged 22 to 28 under carefully controlled conditions. Performance was measured before, during, and after a 120 km stretch of stimulus-deprived, foggy highway that was intended to induce fatigue and stress. Across all trials 69% of the subjects experienced sleep events lasting several seconds, and 7 potentially fatal crashes occurred. Lane tracking behavior degraded by a factor of 2 to 3 prior to each crash. Much of the extensive data acquired by these experiments remains to be analyzed using both standard statistical techniques and highdimensional clustering algorithms. ALISA image-processing software is being applied to video images of the driver eyes and face to detect the onset of sleep and other critical situation

    Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity

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    Trehalose biosynthesis is found in fungi but not humans. Proteins involved in trehalose biosynthesis are essential for fungal pathogen virulence in humans and plants through multiple mechanisms. Loss of canonical trehalose biosynthesis genes in the human pathogen Aspergillus fumigatus significantly alters cell wall structure and integrity, though the mechanistic link between these virulence-associated pathways remains enigmatic. Here we characterize genes, called tslAand tslB, which encode proteins that contain domains similar to those corresponding to trehalose-6-phosphate phosphatase but lack critical catalytic residues for phosphatase activity. Loss of tslA reduces trehalose content in both conidia and mycelia, impairs cell wall integrity, and significantly alters cell wall structure. To gain mechanistic insights into the role that TslA plays in cell wall homeostasis, immunoprecipitation assays coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) were used to reveal a direct interaction between TslA and CsmA, a type V chitin synthase enzyme. TslA regulates not only chitin synthase activity but also CsmA sub-cellular localization. Loss of TslA impacts the immunopathogenesis of murine invasive pulmonary aspergillosis through altering cytokine production and immune cell recruitment. In conclusion, our data provide a novel model whereby proteins in the trehalose pathway play a direct role in fungal cell wall homeostasis and consequently impact fungus-host interactions

    Scientific, Technical and Economic Committee for Fisheries (STECF) - Report of the STECF Study Group on the Evaluation of Fishery Multi-annual Plans (SGMOS 09-02)

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    SG-MOS 09-02 was held in IPIMAR, Lisbon, (Portugal), on 23-27 November 2009. The aim of the workshop was to provide Evaluations of three multiannual fisheries management plans:- R(EC) No 388/2006 ¿ multi-annual plan for sole in the Bay of Biscay; R(EC) No 209/2007 ¿ multi-annual plan for sole in the Western Channel R(EC) No676/2007 ¿ multi-annual plan for sole and plaice in the North Sea. STECF reviewed the report during its Plenary meeting on 26-30 April 2010.JRC.DG.G.4-Maritime affair

    Adverse events related to ultrasound-guided regional anesthesia performed by Emergency Physicians: Systematic review protocol

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    The use of ultrasound-guided regional anesthesia for pain management has become increasingly prevalent in Emergency Medicine, with studies noting excellent pain control while sparing opioid use. However, the use of ultrasound-guided regional anesthesia may be hampered by concern about risks for patient harm. This systematic review protocol describes our approach to evaluate the incidence of adverse events from the use of ultrasound-guided regional anesthesia by Emergency Physicians as described in the literature. This project will also seek to document the scope of ultrasound-guided regional anesthesia applications being performed in Emergency Medicine literature, and potentially serve as a framework for future systematic reviews evaluating adverse events in Emergency Medicine
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