Magnetic aspect sensitivity of high‐latitude E region irregularities measured by the RAX‐2 CubeSat

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106761/1/jgra50801.pd

Radar detection of a localized 1.4 Hz pulsation in auroral plasma, simultaneous with pulsating optical emissions, during a substorm

Many pulsating phenomena are associated with the auroral substorm. It has been considered that some of these phenomena involve kilometer-scale Alfvén waves coupling the magnetosphere and ionosphere. Electric field oscillations at the altitude of the ionosphere are a signature of such wave activity that could distinguish it from other sources of auroral particle precipitation, which may be simply tracers of magnetospheric activity. Therefore, a ground based diagnostic of kilometer-scale oscillating electric fields would be a valuable tool in the study of pulsations and the auroral substorm. In this study we attempt to develop such a tool in the Poker Flat incoherent scatter radar (PFISR). The central result is a statistically significant detection of a 1.4 Hz electric field oscillation associated with a similar oscillating optical emission, during the recovery phase of a substorm. The optical emissions also contain a bright, lower frequency (0.2 Hz) pulsation that does not show up in the radar backscatter. The fact that higher frequency oscillations are detected by the radar, whereas the bright, lower frequency optical pulsation is not detected by the radar, serves to strengthen a theoretical argument that the radar is sensitive to oscillating electric fields, but not to oscillating particle precipitation. Although it is difficult to make conclusions as to the physical mechanism, we do not find evidence for a plane-wave-like Alfvén wave; the detected structure is evident in only two of five adjacent beams. We emphasize that this is a new application for ISR, and that corroborating results are needed

Regulation of spindle orientation and neural stem cell fate in the Drosophila optic lobe.

BACKGROUND: The choice of a stem cell to divide symmetrically or asymmetrically has profound consequences for development and disease. Unregulated symmetric division promotes tumor formation, whereas inappropriate asymmetric division affects organ morphogenesis. Despite its importance, little is known about how spindle positioning is regulated. In some tissues cell fate appears to dictate the type of cell division, whereas in other tissues it is thought that stochastic variation in spindle position dictates subsequent sibling cell fate. RESULTS: Here we investigate the relationship between neural progenitor identity and spindle positioning in the Drosophila optic lobe. We use molecular markers and live imaging to show that there are two populations of progenitors in the optic lobe: symmetrically dividing neuroepithelial cells and asymmetrically dividing neuroblasts. We use genetically marked single cell clones to show that neuroepithelial cells give rise to neuroblasts. To determine if a change in spindle orientation can trigger a neuroepithelial to neuroblast transition, we force neuroepithelial cells to divide along their apical/basal axis by misexpressing Inscuteable. We find that this does not induce neuroblasts, nor does it promote premature neuronal differentiation. CONCLUSION: We show that symmetrically dividing neuroepithelial cells give rise to asymmetrically dividing neuroblasts in the optic lobe, and that regulation of spindle orientation and division symmetry is a consequence of cell type specification, rather than a mechanism for generating cell type diversity.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are

Regulation of spindle orientation and neural stem cell fate in the Drosophila optic lobe

BACKGROUND: The choice of a stem cell to divide symmetrically or asymmetrically has profound consequences for development and disease. Unregulated symmetric division promotes tumor formation, whereas inappropriate asymmetric division affects organ morphogenesis. Despite its importance, little is known about how spindle positioning is regulated. In some tissues cell fate appears to dictate the type of cell division, whereas in other tissues it is thought that stochastic variation in spindle position dictates subsequent sibling cell fate. RESULTS: Here we investigate the relationship between neural progenitor identity and spindle positioning in the Drosophila optic lobe. We use molecular markers and live imaging to show that there are two populations of progenitors in the optic lobe: symmetrically dividing neuroepithelial cells and asymmetrically dividing neuroblasts. We use genetically marked single cell clones to show that neuroepithelial cells give rise to neuroblasts. To determine if a change in spindle orientation can trigger a neuroepithelial to neuroblast transition, we force neuroepithelial cells to divide along their apical/basal axis by misexpressing Inscuteable. We find that this does not induce neuroblasts, nor does it promote premature neuronal differentiation. CONCLUSION: We show that symmetrically dividing neuroepithelial cells give rise to asymmetrically dividing neuroblasts in the optic lobe, and that regulation of spindle orientation and division symmetry is a consequence of cell type specification, rather than a mechanism for generating cell type diversity

Solubility, Light Output and Energy Resolution Studies of Molybdenum-Loaded Liquid Scintillators

The search for neutrinoless double-beta decay is an important part of the global neutrino physics program. One double-beta decay isotope currently under investigation is 100Mo. In this article, we discuss the results of a feasibility study investigating the use of molybdenum-loaded liquid scintillator. A large, molybdenum-loaded liquid scintillator detector is one potential design for a low-background, internal-source neutrinoless double-beta decay search with 100Mo. The program outlined in this article included the selection of a solute containing molybdenum, a scintillating solvent and the evaluation of the mixture's performance as a radiation detector.Comment: 8 pages, 3 figure

The challenge of embedding an ecosystems approach:patterns of knowledge utilisation in public policy appraisal

The ‘ecosystem services approach’ (ESA) to policy making has refocused attention on how knowledge is embedded in policy. Appraisal has long been identified as an important venue for embedding, but suffers from well-known difficulties. This paper examines the extent to which an ESA appears in UK policy appraisal documents, and how far implementing an ESA via appraisal may encounter the same difficulties. A clear understanding of this is vital for interrogating claims that improving knowledge necessarily leads to more sustainable ecosystem management. The paper reports on the content of seventy-five national-level policy appraisals undertaken in the United Kingdom between 2008 and 2012. Only some elements of an ESA appear, with even the environment ministry failing to systematically pick up the concept, which is indeed subject to many of the familiar barriers to embedding environmental knowledge in appraisals. Policy initiatives attempting to institutionalise ecosystem values need to be conversant with these barriers

Comment on "Evidence for Neutrinoless Double Beta Decay"

We comment on the recent claim for the experimental observation of neutrinoless double-beta decay. We discuss several limitations in the analysis provided in that paper and conclude that there is no basis for the presented claim.Comment: A comment written to Modern Physics Letters A. 4 pages, no figures. Updated version, accepted for publicatio