Features of the financial market participants strategy

У статті досліджено зміст стратегії, підходи до її вивчення, складові елементи, засади для розбудови. Розглянуто значення стратегії щодо учасників фінансового ринку, особливості стратегії у досягненні цілей та роль стратегії у їх діяльності. Досліджено напрямки стратегії учасників фінансового ринку.В статье исследовано содержание стратегии, подходы к ее изучению, составные элементы, принципы для развития. Рассмотрены значение стратегии в отношении участников финансового рынка, особенности стратегии в достижении целей и роль стратегии в их деятельности. Исследованы направления стратегии участников финансового рынка.The article examines the content of the strategy, approaches to its study, the components, the foundations for the development. The importance of the strategy for participants in the financial market, the peculiarities of the strategy in achieving the goals and the role of the strategy in their activity are considered. The directions of the strategy of participants in the financial market are explored

Academic Writing for Publication Purposes and Machine Translation: Is the Symbiosis Possible?

The abstracts in Russian and in English are written according to certain rules. For articles written in Russian, an abstract in English is the only means of informing the world scientific community about the authors’ research results. However, the quality of abstracts written in Russian and then translated into English does not always meet the criteria for readability and comply with the accepted academic and publication conventions. This situation might result from the intensive usage of machine translation (MT) systems by authors who do not take into account the guidelines for the input text quality and the limitations inherent in MT systems. The author analyzed the requirements for the input texts and some typical errors in the target ones. The article describes the stages of training masters, postgraduate students and university staff in the effective use of MT systems. The training is based on a bilingual approach, which implies a constant comparison of vocabulary, grammar and style in the native and English languages. The author comes to the conclusion that the effective use of MT systems for writing an abstract in English is possible if the authors have the command of Russian and English at the level sufficient for a concise and unambiguous expression of their thoughts and ideas. Self-censoring is a prerequisite for creating a text that is “understandable” for MT systems. Students must follow simple rules: write sentences of 15-20 words; express one thought per one sentence; use more active verbs; choose nouns that express a specific concept; exclude unnecessary words. At the post-editing stage, learners can use the tools available on the Internet, which allow not only editing the target text, but also will enable learners to acquire independent editing skills

Mapping of multiple muscles with transcranial magnetic stimulation: Absolute and relative test-retest reliability

The spatial accuracy of transcranial magnetic stimulation (TMS) may be as small as a few millimeters. Despite such great potential, navigated TMS (nTMS) mapping is still underused for the assessment of motor plasticity, particularly in clinical settings. Here, we investigate the within‐limb somatotopy gradient as well as absolute and relative reliability of three hand muscle cortical representations (MCRs) using a comprehensive grid‐based sulcus‐informed nTMS motor mapping. We enrolled 22 young healthy male volunteers. Two nTMS mapping sessions were separated by 5–10 days. Motor evoked potentials were obtained from abductor pollicis brevis (APB), abductor digiti minimi, and extensor digitorum communis. In addition to individual MRI‐based analysis, we studied normalized MNI MCRs. For the reliability assessment, we calculated intraclass correlation and the smallest detectable change. Our results revealed a somatotopy gradient reflected by APB MCR having the most lateral location. Reliability analysis showed that the commonly used metrics of MCRs, such as areas, volumes, centers of gravity (COGs), and hotspots had a high relative and low absolute reliability for all three muscles. For within‐limb TMS somatotopy, the most common metrics such as the shifts between MCR COGs and hotspots had poor relative reliability. However, overlaps between different muscle MCRs were highly reliable. We, thus, provide novel evidence that inter‐muscle MCR interaction can be reliably traced using MCR overlaps while shifts between the COGs and hotspots of different MCRs are not suitable for this purpose. Our results have implications for the interpretation of nTMS motor mapping results in healthy subjects and patients with neurological conditions

Development of the infrastructure of the stock market of Ukraine to ensure efficient investment activity: theoretical aspects

Метою статті є визначення особливостей інфраструктури фондового ринку України в контексті забезпечення ефективної інвестиційної діяльності. Досліджено теоретичні основи формування інфраструктури фондового ринку. У статті наведено визначення інфраструктури фондового ринку. Досліджено складові інфраструктури фондового ринку. Визначено цілі та пріоритети розвитку суб’єктів інфраструктури з урахуванням внутрішнього та зовнішнього середовища. Досліджено функціонування фінансових посередників в контексті забезпечення ефективного функціонування фондового ринку. Наведено класифікаційні ознаки фінансових посередників як суб’єктів інфраструктури фондового ринку. Доведено, що інфраструктура фондового ринку інтегрована в інвестиційне середовище учасників фінансового ринку. Практична значимість даної роботи полягає у надані рекомендації щодо удосконалення посередницької діяльності та модернізації інфраструктури фондового ринку України.The purpose of the article is to determine the features of the infrastructure of the stock market of Ukraine in the context of ensuring effective investment activities. The theoretical bases of stock market infrastructure formation are investigated. The article defines the infrastructure of the stock market. The components of the stock market infrastructure are studied. The goals and priorities for the development of infrastructure entities, taking into account the internal and external environment, have been identified. The functioning of financial intermediaries in the context of ensuring the effective functioning of the stock market is studied. The classification features of financial intermediaries as subjects of the stock market infrastructure are given. It is proved that the infrastructure of the stock market is integrated into the investment environment of financial market participants. The practical significance of this work lies in the recommendations provided for the improvement of intermediary activities and modernization of the infrastructure of the stock market of Ukraine

Recurrent versus first cervical artery dissection - a retrospective study of clinical and vascular characteristics

Background and purpose Most recurrent cervical artery dissection (CeAD) events occur shortly after the acute first CeAD. This study compared the characteristics of recurrent and first CeAD events and searched for associations between subsequent events of an individual person. Methods Cervical artery dissection patients with a new CeAD event occurring during a 3-6 month follow-up were retrospectively selected in seven specialized stroke centers. Clinical and vascular characteristics of the initial and the recurrent CeADs were compared. Results The study sample included 76 patients. Recurrent CeADs were occlusive in one (1.3%) patient, caused cerebral ischaemia in 13 (17.1%) and were asymptomatic in 39 (51.3%) patients, compared to 29 (38.2%) occlusive, 42 (55.3%) ischaemic and no asymptomatic first CeAD events. In 52 (68.4%) patients, recurrent dissections affected both internal carotid arteries or both vertebral arteries, whilst 24 (31.6%) patients had subsequent dissections in both types of artery. Twelve (28.6%) of 42 patients with an ischaemic first dissection had ischaemic symptoms due to the recurrent CeADs, too. However, only one (1.3%) of 34 patients with a non-ischaemic first CeAD suffered ischaemia upon recurrence. Conclusion Recurrent CeAD typically affects the same site of artery. It causes ischaemic events less often than the first CeAD. The risk that patients who presented with solely non-ischaemic symptoms of a first CeAD will have ischaemic symptoms in the case of a recurrent CeAD seems very small.Peer reviewe

Дизайн и синтез гидрофобных производных RGD-пептидов

Hydrophobic peptide derivatives containing RGD-amino acids sequence have been synthesized and ability of cationic liposomes to form complexes with DNA has been investigated.Осуществлен синтез гидрофобных производных RGD- и RGDS-пептидов и исследована способность катионных липосом с их включением образовывать комплексы с ДНК

Возможность использования диквертина для лечения остеоартроза в гериатрической практике

Complex treatment of aged and old patients ( n = 60) suffering from deforming osteoarthrosis complicated with reactive synovitis in combination with associated pathology of cardiovascular system is studied. Natural antioxidant dicvertase introduced by ultrasonic waves was used. Positive combined action of ultraphonophoresis by dicvertase was revealed which resulted in lowering pain syndrome, increasing motions range in the affected joint, normalizing of immunity status which allows to broaden indications for the treatment of these patients by lowering the risk of development of pathologic response of the organism on the treatment and facilitates lowering drug loading on patients.Изучена возможность комплексного лечения больных деформирующим остеоартрозом, в том числе осложненным реактивным синовитом, пожилого и старческого возраста (60 пациентов) в сочетании с сопутствующей патологией сердечно-сосудистой системы с использованием природного антиокcиданта диквертина, вводимого ультразвуковыми волнами. Выявлено положительное сочетанное действие ультрафонофореза диквертина, проявившееся в уменьшении болевого синдрома, увеличении объема движений в пораженном суставе, нормализации иммунного статуса, что позволяет расширить показания для лечения этой группы больных, уменьшая риск развития патологической ответной реакции организма на лечение, и способствует снижению медикаментозной нагрузки на пациентов

Pilot Project «All-Russian Registry of Patients with Severe Bronchial Asthma.» The First Results in a Children’s Group of Patients (Moscow’s Observation Program)

The article presents the first results of the pilot observation program «The All-Russian Severe Asthma Patient Registry» which was started in Moscow. Objectives. The objective of this initiative is the accumulation of clinical data on patients with severe bronchial asthma in the Russian Federation. Methods. The chosen method was a registry, the rights holders of which were 3 professional associations — Interregional Public Organization «Russian Respiratory Society», Public Organization «Union of Pediatricians of Russia», All-Russian Public Organization «Association of Allergologists and Clinical Immunologists». Results. The results of the pilot project are presented by the data analysis of electronic case report forms of 36 children (totally, the project included 100 patients, 64 adults and 36 children) enrolled in the program from June to December 2016. Using the registry, a detailed analysis of the clinical characteristics of a group of children with severe atopic bronchial asthma was carried out, the results of a pharmacoepidemiological evaluation of therapy were given. Obtained by the researchers, a high frequency of the assignment of a genetically engineered biologic drug of omalizumab meets the international recommendations but does not reflect the all-Russian reality and can be explained by inclusion in the registry of pediatric patients observed only in the Federal State Autonomous Institution «National Scientific and Practical Center of Children’s Health» of the Ministry of Health of the Russian Federation. Conclusion. To determine true indicators that characterize bronchial asthma in children in the Russian Federation it is necessary, undoubtedly, to expand the geography of project participants