quality of life, sexual satisfaction, anxiety and depression status in lymphoma survivors

Objective: The progressive development of lymphoma therapies has led to an important prolongation of patient survival. We aimed to investigate anxiety, depression, sexual satisfaction and health-related quality of life status in these lymphoma survivors. We examined the effects of depression, anxiety and sexual satisfaction on the quality of life.Materials and methods: In a prospective study, the data were collected from fifty lymphoma survivors. We used six forms. These forms consist of sociodemographic features, the Beck Depression Inventory (BDI), Beck Hopelessness Scala (BHS), State-Trait Anxiety Inventory (STAI I-II), Golombock-Rust Inventory of Sexual Satisfaction (GRISS) and European Organization for Research on the treatment of Cancer Questionnaires Quality of Life (QoL) - C30 questionnaires.Results: The mean age of the patients was 50,2 ± 14,8 (20 – 75) years, and 50% of them were females. In our study, we found that 26% of the patients had high depression values above the cutoff (≥ 17 of BDI score). The mean depression score of the patients was 10,6 ± 8 (0 - 32) and the mean hopelessness score was 5,7 ± 4,5 (0 - 19). The patients whose anxiety and depression scores were high role, cognitive and emotional functioning of EORTC-QLQ-C30 was found statistically significantly low. The mean STAI-I score of the patients was 35,6 ± 11,3 (22-73) and the mean STAI-II score was 41,4 ± 10,6 (23 - 67). Statistical significance in terms of emotional and social functioning was found in the patients with high anxiety scores. When all patients were evaluated with respect to GRISS, we found high scores (&gt; 5) for frequency, communication, vaginusmus and premature ejaculation. We compared the EORTC-QoL-C30 scores and GRISS of the patients. There was an association between emotional dysfunction with high scores of frequency (p = 0.040). Also, there was an association between low scores of role functioning with high scores of avoidance and premature ejaculation (p = 0.015, p = 0.003). However, there was a significant correlation between low scores of global QoL with high scores of avoidance, communication, and touch. There was no statistically significant difference between the anxiety and depression levels of the patient according to gender. But, some functional scales including role function (p = 0.001), social function (p = 0.001) and cognitive function (p = 0.027) were lower in female patients.Conclusion: The lymphoma survivors had high anxiety and depression scores, reduced sexual functioning and low functioning scales of QoL. There was an association between sexual dysfunction low role, emotional functioning and global QoL scores in patients.</p

Prognostic Factors in Elderly Patients with Diffuse Large B-Cell Lymphoma and Their Treatment Results

Objective: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma (NHL). The treatment of older NHL patients has always been a struggle; however, treatment statistics have begun showing favorable results similar to those of younger DLBCL patients thanks to newer treatment protocols. Here, we analyze the progress of our own elderly DLBCL patients who were followed between 2000 and 2016 in our center. Materials and Methods: Eighty-seven DLBCL patients, who were diagnosed and treated in the Dokuz Eylül University Department of Hematology between 2000 and 2016, were included in this study. Median age was 72 (65-89) years and 13 (14.9%) patients were older than 80 years. Results: Median follow-up time was 19 months and 45 patients (51.7%) died during the follow-up period. Median overall survival (OS) was 55 months and median progression-free survival was calculated as 27 months. Sixty-three patients (72.4%) received standard R-CHOP therapy. Complete response was seen in 46 (52.9%) patients. The median survival time for patients who had complete response was 136 months (p80 years) and younger patients (p=0.236). Conclusion: According to our findings, we think that being able to complete standard R-CHOP therapy is vital for the survival rate of elderly DLBCL patients

Disappearance of Biodiversity and Future of Our Foods

“I. Uluslararası Organik Tarım ve Biyoçeşitlilik Sempozyumu 27-29 Eylül Bayburt