420 research outputs found

    Chemical Characterization and Source Apportionment of Household Fine Particulate Matter in Rural, Peri-urban, and Urban West Africa

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    Household air pollution in sub-Saharan Africa and other developing regions is an important cause of disease burden. Little is known about the chemical composition and sources of household air pollution in sub-Saharan Africa, and how they differ between rural and urban homes. We analyzed the chemical composition and sources of fine particles (PM2.5) in household cooking areas of multiple neighborhoods in Accra, Ghana, and in peri-urban (Banjul) and rural (Basse) areas in The Gambia. In Accra, biomass burning accounted for 39–62% of total PM2.5 mass in the cooking area in different neighborhoods; the absolute contributions were 10–45 μg/m3. Road dust and vehicle emissions comprised 12–33% of PM2.5 mass. Solid waste burning was also a significant contributor to household PM2.5 in a low-income neighborhood but not for those living in better-off areas. In Banjul and Basse, biomass burning was the single dominant source of cooking-area PM2.5, accounting for 74–87% of its total mass; the relative and absolute contributions of biomass smoke to PM2.5 mass were larger in households that used firewood than in those using charcoal, reaching as high as 463 μg/m3 in Basse homes that used firewood for cooking. Our findings demonstrate the need for policies that enhance access to cleaner fuels in both rural and urban areas, and for controlling traffic emissions in cities in sub-Saharan Africa

    Experimental and theoretical study of line mixing in methane spectra. IV. Influence of the temperature and of the band

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    The infrared bands line-mixing effects of methane perturbed by nitrogen were discussed at different pressures. The spectral shapes of the ν2, ν4 and ν3 bands were compared at room temperature while the ν3 region was employed for the investigation of thermal effects. The effects of collisions in the ν4 region's spectra were calculated at the room temperature. The Coriolis coupling between ν2 and ν4 vibrational states resulted in the failure of evolution modeling with increasing pressure of absorption.© 2000 American Institute of PhysicsPeer Reviewe

    Seedlings quality of Bertholletia excelsa Bonpl. (Lecythidaceae) produced in forest nursery.

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    Neste estudo, a qualidade das mudas de Bertholletia excelsa foi avaliada em relação ao tamanho da muda transplantada. Trinta dias após o transplante das mudas para o viveiro florestal, foi realizada a primeira medição de altura. A partir do 30º dia, as avaliações foram realizadas a cada 15 dias, sendo nove no total. O Índice de Qualidade de Dickson (DQI) foi avaliado para determinar a qualidade das mudas, onde todas as mudas tiveram suas raízes podadas. O delineamento experimental, totalizando 160 indivíduos, foi totalmente casualizado com quatro tratamentos e quatro repetições, incluindo o corte da parte aérea e três tamanhos de plântulas sem corte da parte aérea. As mudas cortadas pela parte aérea apresentaram um DQI de 0,66 ± 0,23, significativamente maior do que as mudas grandes (<17 cm de altura) sem corte da parte aérea (F3,76 = 2,762, p = 0,047). O transplante teve efeitos significativos sobre o desenvolvimento, crescimento e qualidade das mudas de Bertholletia excelsa durante os primeiros 165 dias de produção de mudas. Portanto, a poda da parte aérea resultou em melhor desempenho das mudas de B. excelsa para serem plantadas no campo

    What traits are carried on mobile genetic elements, and why?

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    Although similar to any other organism, prokaryotes can transfer genes vertically from mother cell to daughter cell, they can also exchange certain genes horizontally. Genes can move within and between genomes at fast rates because of mobile genetic elements (MGEs). Although mobile elements are fundamentally self-interested entities, and thus replicate for their own gain, they frequently carry genes beneficial for their hosts and/or the neighbours of their hosts. Many genes that are carried by mobile elements code for traits that are expressed outside of the cell. Such traits are involved in bacterial sociality, such as the production of public goods, which benefit a cell's neighbours, or the production of bacteriocins, which harm a cell's neighbours. In this study we review the patterns that are emerging in the types of genes carried by mobile elements, and discuss the evolutionary and ecological conditions under which mobile elements evolve to carry their peculiar mix of parasitic, beneficial and cooperative genes

    Civil society mobilisation after Cyclone Tracy, Darwin 1974

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    Major disasters challenge or exceed the capacity of the official emergency management sector to provide needed rescue services, support and relief. Emergency services in most jurisdictions do not have the surge capacity for unusual or extreme events without drawing on other jurisdictions or local people from outside the formal emergency management organisations. In such circumstances, those in the affected area need to organise themselves and make maximum use of local resources to cope with the immediate aftermath of impact. To find the required surge capacity, this suggests a whole of society response with the official system working with the capacities of people, commerce and organisations outside the emergency sector. An example is provided by the destruction of the northern Australian capital city of Darwin by Cyclone Tracy in December 1974. Informal volunteering and emergent leadership in Darwin and across Australia were critical to the immediate response and relief. Volunteering was widespread and worked well alongside official emergency management. With today’s information and communication technologies and a strong national resilience narrative, we would expect to do at least as well. However, governments now exercise much more control over civil society. We examine the implications for surge capacity and adaptability

    Processamento e estabilidade de uma bebida de caju e yacon durante o armazenamento sob refrigeração.

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    Made available in DSpace on 2018-05-26T00:36:59Z (GMT). No. of bitstreams: 1 ART18019.pdf: 661145 bytes, checksum: 89b2f029a8a4dd9a67ddee6c52f6efe1 (MD5) Previous issue date: 2018-05-24bitstream/item/177700/1/ART18019.pd

    Proteômica plasmática quantitativa de pacientes sobreviventes e não sobreviventes de COVID-19 internados no hospital revela potenciais biomarcadores prognósticos e alvos terapêuticos

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    O desenvolvimento de novas abordagens que permitam a avaliação precoce de quais casos de COVID-19 provavelmente se tornarão críticos e a descoberta de novos alvos terapêuticos são importantes. Neste estudo de coorte, foi avaliado o perfil proteômico e laboratorial do plasma de 163 pacientes internados no Hospital Estadual de Bauru (Bauru, SP, Brasil) entre 4 de maio e 4 de julho de 2020, que foram diagnosticados com COVID-19 por RT-PCR a partir de amostras de swab nasofaríngeo amostras. Amostras de plasma foram coletadas na admissão para análises laboratoriais de rotina e análise proteôomica quantitativa shotgun livre de marcadores. De acordo com o curso da doen ça, os pacientes foram divididos em 3 grupos: a) Sintomas leves, com alta sem interna ção em unidade de terapia intensiva (UTI) (n=76); b) Sintomas graves, alta após admissão em UTI (n=56); c) Críticos, faleceram após admissão em UTI (n=31). Os glóbulos brancos e os neutrófilos foram significativamente maiores em pacientes graves e críticos em compara ção com os leves. Os linfócitos foram significativamente menores nos pacientes críticos em rela ção aos leves e as plaquetas foram significativamente menores nos pacientes críticos em rela ção aos leves e graves. Ferritina, TGO, uréia e creatinina foram significativamente maiores nos pacientes críticos em rela ção aos leves e graves. Albumina, CPK, LDH e dímero D foram significativamente maiores nos pacientes graves e críticos em compara ção aos leves. A PCR foi significativamente maior em pacientes graves em compara ção com os leves. A análise proteómica revelou mudan ças marcantes entre os grupos nas proteínas plasmáticas relacionadas à ativa ção do complemento, coagula ção sanguínea, resposta inflamatória aguda e resposta imune. Pacientes críticos apresentaram níveis mais elevados de proteínas associadas CLEC4, CCL24, SAA1, SAA2, 2-M, PCR e níveis reduzidos de proteínas associadas ao sistema imune e complemento, como CD5L e VDBP, AHSG e PGLYRP2. Pacientes com sintomas leves apresentaram maiores níveis de proteínas protetoras, como PGLYRP2, APOH e PON-1. Nossos resultados indicam várias proteínas plasmáticas envolvidas na patogênese da COVID-19 que podem serúteis para predizer o prognóstico da doen ça quando analisadas na admissão dos pacientes no hospital. A valida ção de algumas destas. Confirmando-se o seu papel, as vias envolvendo estas proteínas podem ainda ser novos alvos terapêuticos em potencial para a COVID-19
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