Long-Term Outcomes Of Vitrectomy And Internal Limitıng Membrane Peeling For Myopic Foveschisis

INTRODUCTION: To evaluate the long-term results of pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) peeling in patients with myopic foveoschisis (MF) METHODS: In this retrospective study, the medical records of the patients who underwent PPV combined with ILM peeling due to myopic foveoschisis were examined. The best corrected visual acuity (BCVA) and the change in BCVA were evaluated. Preoperatively fovea detachment (FD), presence of postoperative ellipsoid zone defect (EZD), and preoperative and postoperative central macular thickness (SMC) were evaluated using optical coherence tomography (OCT). RESULTS: Twenty-five eyes of 20 patients were included in the study. The mean preoperative BCVA was 1.41 +- 0.32 logMAR (1.0-1.8 logMAR) and postoperative BCVA was 0.87 +- 0.41 logMAR (0.3-1.8 logMAR). Postoperative visual acuity improved in 20 eyes (80%). Postoperatively, 4 eyes (16%) had no change in visual acuity and 1 eye (4%) had a decrease in visual acuity. The mean CMT was 683.8 µm +- 155.4 and 262.6 µm +- 46.5 preoperatively and postoperatively, respectively. There was a significant decrease in CMT in the first year after surgery when it was compared with the preoperative CMT (p <0.001). In 20 (80%) eyes, foveoschisis was completely resolved anatomically in the first year after surgery. In 5 eyes (20%), there was a decrease in CMT in the OCT, and a partial improvement in the foveoschisis. DISCUSSION AND CONCLUSION: It is concluded that vitrectomy combined with ILM peeling in the treatment of myopic foveoschisis is an effective and reliable surgical method for increasing visual acuity and providing anatomical improvement

Flow Field Investigation of Rib Roughened Serpentine channel

This paper presents numerical flow field and heat transfer analysis of a channel consisting of upstream and downstream channels and a 180° bend. Turbulators (rib) with a square cross-section are placed in the straight part of the channels in order to enhance the heat transfer while flow enters to the model at fully developed conditions at Reynolds numbers of 20000. A constant heat flux boundary condition is provided from the bottom wall of the model. Numerical simulations are performed by a commercial solver using realizable k-ε turbulence model with enhanced wall treatment. The flow field development and evaluation of pressure drop accounted by each rib are analyzed along the channel. The effects of ribs to the flow field are characterized by wall shear distribution. The effect of u-bend on the downstream flow field is investigated

Dexamethasone Implant as an Adjunct Therapy in Refractory Diabetic Macular Edema: Real-World Experience in a Turkish Population.

INTRODUCTION: To evaluate,in a real-world setting, the effects of intravitreal dexamethasone (DEX) implants in patients with refractory diabetic macular edema after 3 initial anti-vascular endothelial growth factor (anti-VEGF) injections. METHODS: Each enrolled patient received a DEX implant after suboptimal response to 3 monthly anti-VEGF injections and was followed for 12 months. A second DEX implant was allowed at least 6 months later. Anti-VEGF injections were administered on a pro re nata (PRN) regimen after DEX implant. Predictive factors for visual and morphological outcomes and additional therapies during follow-up were evaluated. RESULTS: Among 81 included eyes, mean central macular thickness (CMT) decreased from 583+-178 µm to 259+-119 µm, and 28 eyes (35%) gained more than 5 ETDRS letters after 1 month. Visual acuity significantly improved most commonly in patients with intact ellipsoid zones. The decrease in CMT was positively correlated with baseline CMT and cyst size. Despite the PRN protocol, significant losses in improvements were seen after 6 months compared to 1 month in the percentage of eyes with CMTs smaller than 300 µm (47% vs 75%) and losing at least5 ETDRSletters (16% vs 5%; P <0.001). The values at 6 and 12 months were not statistically different. DISCUSSION AND CONCLUSION: A DEX implant is an option in eyes with suboptimal responses to 3 monthly anti-VEGF injections. In a real-world setting, anti-VEGF injections on a PRN regimen is not sufficient to preserve the benefits of a DEX implant for a period of 6 months

Patient-controlled analgesia - Comparison of morphine to Dexmedetomidine plus morphine in patients undergoing laminectomy

WOS: 000258715700005The aim of this study was to compare the analgesic effect of patient-controlled morphine with that of patient-controlled morphine plus dexmedetomidine oil postoperative pain in patients undergoing laminectomy. Ethics committee of the institute approved this Study. and after a written informed consent obtained from each participant, 64 patients with American Society of Anesthesiologist physical status I and II, scheduled for laminectomy were recruited for this prospective, randomized controlled Study. A standardized load morphine dose of 0.15 mg/kg was given to all patients. Patients were randomized into 2 groups postoperatively. The settings were IV morphine, bolus dose 0.02mg/kg, with a lock out time of 15 minutes in group morphine (n = 32). The settings were bolus dose 0.02 mg/kg and 0.1 mu g/k dexmedetomidine with a lock out time of 15 minutes in group morphine Plus dexmedetomidine (n = 32). Hemodynamic variables, pain scores, and sedation scores were recorded postoperatively. No differences were detected in the demographic data, hemodynamic variables, and pain scores. Total morphine consumption was 46.37 +/- 12.05 mg in group morphine and 16.03 +/- 8.55 mg in group morphine plus dexmedetomidine. Sedation scores were significantly higher ill group morphine plus dexmedetomidine after the first hour. Using morphine or morphine plus dexmedetomidine in patient-controlled analgesia provided effective postoperative analgesia. In the morphine plus dexmedetomidine group, postoperative morphine consumption was lesser than that of the group with only morphine. This result may be explained as a synergistic effect of dexmedetomidine with the analgesic action of morphine

Awareness of patients with impacted teeth about impacted teeth in Turkey: A questionnaire study

Objective: The aim of this study is to evaluate the knowledge and awareness levels of patients who have at least one impacted tooth and who had previously applied to the dentist. Study design: This study was conducted in patients aged 15 years and older who applied to Ordu University Faculty of Dentistry for routine examination and agreed to fill out the questionnaire form. A total of 325 people participated in the survey conducted to determine the awareness of patients applying to the faculty of dentistry about their existing impacted teeth. A Pearson's chi-square test was used for hypothesis testing when expected frequencies exceeded 5. Results: It was determined that 56.9 % (185) of the participants were aware of their existing teeth, while 43.1 % (140) were not aware. When the patients were evaluated according to the institutions they had visited, it was seen that the group who were most aware of the presence of impacted tooth were those who apply to the faculty of dentistry (74.4 %). The rate of being informed by dentists in the institutions that they had previously visited was higher in patients with university or post-university graduates (p < 0.05). The most common information given by the dentists to the patients about their impacted dental problems was that the tooth should be followed up (40.4 %), while the removal of the tooth constituted 28.4 % of the information given. Conclusion: This study showed that although patients are aware of their existing impacted teeth, their level of knowledge about the risks it may pose is low. For a healthy oral care and health, patients should be adequately informed about impacted teeth

Severity of Maternal SARS-CoV-2 Infection in Pregnancy Predicts Neonatal Outcomes

Objective The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak had an enormous global impact. Pregnant women with SARS-CoV-2 appear to have higher morbidity and mortality. This study aimed to evaluate the effect of the severity of maternal SARS-CoV-2 infection on neonatal outcomes. Study Design The clinical and laboratory data of 40 women and neonates evaluated retrospectively. Results This retrospective study showed that SARS-CoV-2 infection had an adverse impact on neonatal outcomes proportionally with the maternal disease severity including increased prematurity rates, postnatal resuscitation need, prolonged hospital stay and longer ventilatory support requirement in infants born to mothers with moderate or severe disease. Conclusion Maternal disease severity had adverse effects on neonatal outcomes. The severity of maternal disease was found to be associated with increased rates of prematurity, requirement of postnatal resuscitation, prolonged hospital stay, and longer ventilatory support