Development and parametric evaluation of the prototype 2 and 3 flash evaporators

Development of the Prototype 2 and 3 flash evaporator heat sinks which vaporize an expendable fluid to cool a heat transport fluid loop is reported. The units utilize Freon 21 as the heat transport fluid and water as the expendable fluid to meet the projected performance requirements of the space shuttle for both on-orbit and ascent/reentry operations. The evaporant is pulse-sprayed by on-off control onto heat transfer surfaces containing the transport fluid and exhausted to the vacuum environment through fixed area exhaust ducts

Sociocultural Risk Factors for Elevated Perceived Stress among African American Smokers

Introduction: African Americans experience unique stressors that may inhibit smoking cessation and enhance relapse rates. Few studies, however, have focused on risk factors for perceived stress among treatment seekers. Because African Americans are less likely to quit compared to the larger community, understanding factors associated with perceived stress among smokers has the potential to improve intervention outcomes. This study examined psychosocial and cultural correlates of stress in a sample of African American participants in a randomized controlled trial. Methods: At baseline, participants reported demographic factors and completed assessments of smoking history, alcohol use, friend and household smoking, weight concerns, acculturation, depressive symptoms, and perceived stress (N = 325). Bivariate associations were examined, followed by multiple regression analyses to test independent relationships. The sample was comprised of mostly middle-aged males, with at least a high school education, who were single, and reported low household income. Participants were moderately nicotine dependent and smoked 18 cigarettes per day for 26 years. Results: Perceived stress was inversely associated with age (r = -.16, p = .004), education (r = -.11, p = .04), household income (r = -.11, p = .047), and positively associated with being male (r = .13, p = .02). Stress perceptions were positively related to cigarettes per day (r = .11, p = .049), nicotine dependence (r = .20, p = .001), drinking frequency (r = .15, p = .008), drinking intensity (r = .14, p=.02), and inversely related to smoking duration (r = -.12, p = .03). We found positive associations between perceived stress and household smokers (r = .18, p = .004), and friends who smoke (r = .15, p = .01). Perceived stress was also positively associated with post-cessation weight concern (r = .14, p = .01), a traditional African American cultural orientation; r = .12, p = .04), and depressive symptoms (r = .65, p Conclusion: These findings have important intervention implications. Many of the risk factors for distress among African American smokers are modifiable. Interventions should prioritize addressing depression, household smoking environment, and stress among younger smokers, in addition to managing other stress-enhancing concerns like alcohol use

Governing Legal Embodiment: On the Limits of Self-Declaration

This article presents the first empirically-based and theoretically-informed investigation of the effectiveness of the ‘self-declaration model’ of legal gender recognition in Denmark, the first European state to adopt it. Drawing upon analysis of legislative materials, as well as interviews with stakeholders in the legislative process and trans and intersex legal subjects, it contends that self-declaration is not without its limitations. By conceptualising embodiment as an ontological and epistemological process of becoming, and emphasising the institutional dimensions and effects of such processes, it demonstrates that self-declaration may not address the complexities of legal embodiment, particularly concerning restrictions on trans and intersex people’s access to health care. The article’s empirical findings are directed towards the policymakers and activists tasked with shaping reforms of gender recognition legislation in the UK and elsewhere. The analytical agenda it develops may be adopted, and adapted, by scholars working in this area and other regulatory contexts

Mandibuloacral Dysplasia Caused by LMNA Mutations and Uniparental Disomy.

Mandibuloacral dysplasia (MAD) is a rare autosomal recessive disorder characterized by postnatal growth retardation, craniofacial anomalies, skeletal malformations, and mottled cutaneous pigmentation. Hutchinson-Gilford Progeria Syndrome (HGPS) is characterized by the clinical features of accelerated aging in childhood. Both MAD and HGPS can be caused by mutations in the LMNA gene. In this study, we describe a 2-year-old boy with overlapping features of MAD and HGPS. Mutation analysis of the LMNA gene revealed a homozygous missense change, p.M540T, while only the mother carries the mutation. Uniparental disomy (UPD) analysis for chromosome 1 showed the presence of maternal UPD. Markers in the 1q21.3-q22 region flanking the LMNA locus were isodisomic, while markers in the short arm and distal 1q region were heterodisomic. These results suggest that nondisjunction in maternal meiosis followed by loss of the paternal chromosome 1 during trisomy rescue might result in the UPD1 and homozygosity for the p.M540T mutation observed in this patient

Neural correlates of intrusion of emotion words in a modified Stroop task

Behavioural studies have demonstrated that the emotional Stroop task is a valuable tool for investigating emotion-attention interactions in a variety of healthy and clinical populations, showing that participants are typically more distracted by negative stimuli as compared to neutral or positive stimuli. The main aim of this study was to find and examine the neural correlates of this greater intrusion from negative emotional stimuli. Reliable reaction time (RT) and event-related potential (ER-P) data were collected from 23 participants who performed a manual emotional Stroop, task with short (40 ins) and long (500 ms) inter-trial intervals. In the short interval condition, participants were found to produce longer RTs for negative than neutral words, suggesting that these stimuli were more difficult to ignore. This RT effect disappeared in the long interval condition, although larger PI amplitudes were found for the negative words. This suggests that differences in early attention allocation may be unrelated to the degree of intrusion at the behavioural level. In addition, a larger negative slow wave around 300-700 ms post-stimulus was observed in the long interval condition, but only for those negative words that produced prolonged RTs as compared to their matched controls. This late and broadly distributed effect is believed to reflect suppression of meaning representations

Radiator design system computer programs

Minimum weight space radiator subsystems which can operate over heat load ranges wider than the capabilities of current subsystems are investigated according to projected trends of future long duration space vehicles. Special consideration is given to maximum heat rejection requirements of the low temperature radiators needed for environmental control systems. The set of radiator design programs that have resulted from this investigation are presented in order to provide the analyst with a capability to generate optimum weight radiator panels or sets of panels from practical design considerations, including transient performance. Modifications are also provided for existing programs to improve capability and user convenience