The interaction of images and text during comprehension of garden-path sentences: is integration better than good enough?

One of the main goals of reading is to construct a discourse representation. However, when information in the discourse is confusing or ambiguous, readers are often not able to create a fluid, accurate understanding of the text. Decades of research on temporarily ambiguous garden-path sentences have given the field of psycholinguistics a comprehensive understanding of how readers process, and often misinterpret, garden-path sentences. Both online and offline data demonstrate that when reading garden-path sentences (e.g., As the guard and officer wrestled the thief that was fleeing fell down the stairs), readers may not arrive at the correct, syntactically-licensed interpretation (i.e., that the guard and officer are wrestling each other) despite apparent reanalysis. The garden-path sentence processing model claims that readers often parse sentences by developing only shallow representations of the structure, and thus never return from "down the garden path" to arrive at the correct, syntactically licensed interpretation (Ferreira, Ferraro, & Bailey, 2002; Ferreira & Patson, 2007). In this dissertation, I seek to test the bounds of the garden-path model of sentence processing by investigating contextual influences on language processing. Specifically, how are reading processes are affected by the presence of extralinguistic information (e.g., imagery) with garden-path sentences. If readers are able to properly make use of linguistic (words) and nonlinguistic (pictorial) information, does it help them avoid inaccurate interpretation? For means of comparison, a related question is the role of imagery on linguistic disambiguation for less proficient readers who might rely more on the nonlinguistic code (e.g., nonnative speakers). I approach the issue of visual and linguistic (multimedia) processing by investigating specifically whether or not nonnative speakers of English, compared to native speakers, rely differently on non-linguistic information to parse and understand ambiguous, garden-path sentences

Results and adverse events of personalized peptide receptor radionuclide therapy with 90Yttrium and 177Lutetium in 1048 patients with neuroendocrine neoplasms

Peptide receptor radionuclide therapy (PRRT) of patients with somatostatin receptor expressing neuroendocrine neoplasms has shown promising results in clinical trials and a recently published phase III study.In our center, 2294 patients were screened between 2004 and 2014 by 68Ga somatostatin receptor (SSTR) PET/CT. Intention to treat analysis included 1048 patients, who received at least one cycle of 90Yttrium or 177Lutetium-based PRRT. Progression free survival was determined by 68Ga SSTR-PET/CT and EORTC response criteria. Adverse events were determined by CTCAE criteria.Overall survival (95% confidence interval) of all patients was 51 months (47.0-54.9) and differed significantly according to radionuclide, grading, previous therapies, primary site and functionality. Progression free survival (based on PET/CT) of all patients was 19 months (16.9-21), which was significantly influenced by radionuclide, grading, and origin of neuroendocrine neoplasm. Progression free survival after initial progression and first and second resumption of PRRT after therapy-free intervals of more than 6 months were 11 months (9.4-12.5) and 8 months (6.4-9.5), respectively. Myelodysplastic syndrome or leukemia developed in 22 patients (2.1%) and 5 patients required hemodialysis after treatment, other adverse events were rare.PRRT is effective and overall survival is favorable in patients with neuroendocrine neoplasms depending on the radionuclide used for therapy, grading and origin of the neuroendocrine neoplasm which is not exactly mirrored in progression free survival as determined by highly sensitive 68Ga somatostatin receptor PET/CT using EORTC criteria for determining response to therapy

Redesigning urban infrastructures for a low-emission future : an overview of urban low-carbon technologies

Preventing the worst consequences of climate change would require that GHG emissions be reduced to levels near zero by the middle of the century. To respond to such a daunting challenge, we need to rethink and redesign the currently highly energy-dependent infrastructures of industrial societies and particularly the urban infrastructures to become low- or even zero-carbon cities. Sustainable urban infrastructures need technology. In this paper focused on Western European Cities, we discuss a wide set of technologies in the fields of building, energy and transport infrastructures that can significantly contribute to a reduction of energy and/or GHG emissions and are already available or are in the pipeline. Based on the review of a recent study for the city of Munich, we then present how a mix of these technologies could reduce CO2-emissions by up to 90% for the metropolis of 1.3 million inhabitants and that this strategy could be economically attractive despite a high initial investment. All of the residential buildings of a city like Munich could be entirely redesigned for EUR 200 per inhabitant annually, which is about one third of an average annual natural gas bill

Strompreise Ost - West

Available from Bibliothek des Instituts fuer Weltwirtschaft, ZBW, D-21400 Kiel C 203165 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

Smart City - Bausteine auf dem Weg zu einer CO2-armen Stadt

Die Städte tragen weltweit am stärksten zum Klimawandel bei. Wer mit dem Klimaschutz ernst machen will, muss also dort ansetzen. Eine Metropole in einen weitgehend CO2-freien Ballungsraum umzuwandeln, ist eine sehr anspruchsvolle, aber machbare Aufgabe, die natürlich nicht umsonst zu haben ist, sich im Großen und Ganzen aber rechnet. Wie eine aktuelle Studie zeigt, lässt sich die weitgehende CO2-Freiheit aber nur realisieren, wenn der gesamte Entwicklungsprozess der urbanen Infrastrukturen in die Stadt-, Gebäude-, Verkehrs- und Energieplanung sowie in die Investitionsentscheidungen der privaten Akteure vorrangig integriert wird. Und wenn alle mitziehen: Verwaltungen, Stadtplaner, Energieversorger und der Bürger

Effizienz von Maßnahmen zur Verbrauchseinschränkung bei Mineralölversorgungsstörungen

Ziel der Studie ist es, die auf der Basis des Energiesicherungsgesetzes von 1975 vorgesehenen Verordnungen, mit denen im Falle von Versorgungsproblemen bei Mineralöl und Mineralölerzeugnissen drosselnd in den inländischen Ölmarkt eingegriffen werden kann, auf ihr Einsparpotential hin zu überprüfen. Die Berechnung der Effizienz von verbrauchseinschränkenden Maßnahmen erfolgte für das Referenzjahr 1992 sowie perspektivisch für 2005.Alle vom Gesetzgeber für den Krisenfall vorgesehenen Maßnahmen der sogenannten "leichten Hand" wurden zunächst daraufhin überprüft, welche Einsparpotentiale bei jeweils isoliertem Einsatz zu erwarten wären, und zwar getrennt für den nicht-verkehrlichen Bereich (private Haushalte, Kleinverbraucher, Industrie) und den Verkehrsbereich (z.B. Tempolimits und Fahrverbote). Anschließend wurden diese Maßnahmen bei simultanem Einsatz (in plausiblen Kombinationen) auf ihre mengenmäßigen Wirkungen hin untersucht.In einem weiteren Arbeitsschritt wurden die Einsparpotentiale von Rationierungsmaßnahmen geschätzt. Diese Maßnahmen der sogenannten "harten Hand" zur Deckung des lebenswichtigen Bedarfs sollen dann zur Anwendung kommen, wenn es sich um eine gravierende Mineralölversorgungskrise handelt, die mit den zuvor untersuchten Maßnahmen der "leichten Hand" nicht mehr überbrückt werden kann.Darüber hinaus wurde im Verkehrsbereich auf Monats- und Quartalsebene geprüft, inwieweit der Zeitpunkt des Eintritts einer Krise jeweils die Höhe der Einsparpotentiale beeinflußt und welche Auswirkungen von durch Einschränkungen des motorisierten Individualverkehrs bewirkten Verkehrsverlagerungen zum öffentlichen Verkehr dort zu erwarten sind.Abschließend sind die je nach verbrauchseinschränkender Maßnahme unterschiedlichen ökonomischen Rückwirkungen einer qualitativen Würdigung unterzogen worden

Neoadjuvant peptide receptor radionuclide therapy for an inoperable neuroendocrine pancreatic tumor

Pancreatic endocrine tumors are rare but are among the most common neuroendocrine neoplasms of the abdomen. At diagnosis many of them are already advanced and difficult to treat. We report on an initially inoperable malignant pancreatic endocrine tumor in a 33-year-old woman, who received neoadjuvant peptide receptor radionuclide therapy (PRRT) as first-line treatment. This resulted in a significant downstaging of the tumor and allowed its subsequent complete surgical removal. Follow-up for eighteen months revealed a complete remission. This is the first report on neoadjuvant PRRT in a neuroendocrine neoplasm with subsequent successful complete resection

Geochemistry of lower and middle Keuper sediments in the Central Thuringian Syncline

Cuttings of Lower and Middle Keuper sediments of the INFLUINS-drilling in the central Thuringian Syncline were geochemically analysed. Indications about shifting depositional environments are interpreted from ratios of whole-rock element contents. For the middle part of sandstone cycle S 2 high heavy metal contents imply precipitation of sufidic ores during a short marine interval. Element contents are compared with potential source rocks in the southern part of the Baltic Shield, in the Lausitz Anticline Zone, in the Erzgebirge, in the moldanubian part, in the broad sense, of the Bohemian Massif, in the Münchberg Gneiss Massif and the Fichtelgebirge. The geochemical coincidence of investigated Keuper sediments is highest with grantioid and gabbroic rocks of southern Scandinavia. Granodiorite rocks of the Lausitz are also possible sources, whereas granites of the Fichtelgebirge and the Bohemian Massif are less probable