Lentivirus tethering to the genome is associated with transcription factor binding sites that favour virus survival

Poster Presentation PXXX, presented at the ESGCT 28th Annual Congress In collaboration with BSGCT Virtual Conference, October 19–22, 2021...

The global distribution and population at risk of malaria: past, present, and future

The aim of this review was to use geographic information systems in combination with historical maps to quantify the anthropogenic impact on the distribution of malaria in the 20th century. The nature of the cartographic record enabled global and regional patterns in the spatial limits of malaria to be investigated at six intervals between 1900 and 2002. Contemporaneous population surfaces also allowed changes in the numbers of people living in areas of malaria risk to be quantified. These data showed that during the past century, despite human activities reducing by half the land area supporting malaria, demographic changes resulted in a 2 billion increase in the total population exposed to malaria risk. Furthermore, stratifying the present day malaria extent by endemicity class and examining regional differences highlighted that nearly 1 billion people are exposed to hypoendemic and mesoendemic malaria in southeast Asia. We further concluded that some distortion in estimates of the regional distribution of malaria burden could have resulted from different methods used to calculate burden in Africa. Crude estimates of the national prevalence of Plasmodium falciparum infection based on endemicity maps corroborate these assertions. Finally, population projections for 2010 were used to investigate the potential effect of future demographic changes. These indicated that although population growth will not substantially change the regional distribution of people at malaria risk, around 400 million births will occur within the boundary of current distribution of malaria by 2010: the date by which the Roll Back Malaria initiative is challenged to halve the world's malaria burden

Biodiversity and Taxonomy of the Parasitic Crustacea

Crustaceans have independently adopted a parasitic mode of life on numerous occasions, and this chapter reviews the classification and species richness of each of the parasitic clades, which lie within two major pancrustacean lineages, the Multicrustacea and the Oligostraca. Tabulated data are presented on the genera, species richness and host usage of the whale lice (Cyamidae); the generic and species richness of the families of hyperiidean amphipods; the generic and species richness and the host usage of the families and subfamilies of epicaridean isopods; the species richness, salinity regime and host taxon of cymothoid isopods; the generic and species richness and the host usage of the families of Ascothoracida and Rhizocephala; the species of Tantulocarida and their hosts; the generic and species richness and the host usage of the families and family-level groupings of cyclopoid and siphonostomatoid copepods; the species richness and salinity regimes of the genera of Branchiura; and the species richness and host usage of the genera of tongue worms (Pentastomida). Parasitic crustaceans use a total of 15 different phyla as hosts