2,763 research outputs found
Organic cathode for a secondary battery
A liquid catholyte for a battery based on liquid metal such as sodium anode and a solid, ceramic separator such as beta alumina (BASE) comprises a mixture of a Group I-III metal salt such as sodium tetrachloroaluminate and a minor amount of an organic carbonitrile depolarizer having at least one adjacent ethylenic band such as 1 to 40 percent by weight of tetracyanoethylene. The tetracyanoethylene forms an adduct with the molten metal salt
Resonant Scattering and Recombination in CAL 87
The eclipsing supersoft X-ray binary CAL 87 has been observed with Chandra on
August 13/14, 2001 for nearly 100 ksec, covering two full orbital cycles and
three eclipses. The shape of the eclipse light curve derived from the
zeroth-order photons indicates that the size of the X-ray emission region is
about 1.5 solar radii. The ACIS/LETG spectrum is completely dominated by
emission lines without any noticeable continuum. The brightest emission lines
are significantly redshifted and double-peaked, suggestive of emanating in a
2000 km/s wind. We model the X-ray spectrum by a mixture of recombination and
resonant scattering. This allows us to deduce the temperature and luminosity of
the ionizing source to be kT = 50-100 eV and L_X = 5E37 erg/s.Comment: To appear in Proceedings of IAU Coll. 194 "Compact binaries in the
Galaxy and beyond" (Rev. Mex. A&A Conf. Series), eds. G. Tovmassian and E.
Sio
Functional Characterization of the Plasmacytoma Variant Translocation 1 Gene (PVT1) in Diabetic Nephropathy
We previously observed association between variants in the plasmacytoma variant translocation 1 gene (PVT1) and end-stage renal disease (ESRD) attributed to both type 1 and type 2 diabetes, and demonstrated PVT1 expression in a variety of renal cell types. While these findings suggest a role for PVT1 in the development of ESRD, potential mechanisms for involvement remain unknown. The goal of this study was to identify possible molecular mechanisms by which PVT1 may contribute to the development and progression of diabetic kidney disease. We knocked-down PVT1 expression in mesangial cells using RNA interference, and analyzed RNA and protein levels of fibronectin 1 (FN1), collagen, type IV, alpha 1 (COL4A1), transforming growth factor beta 1 (TGFB1) and plasminogen activator inhibitor-1 (SERPINE1 or PAI-1) by qPCR and ELISA, respectively. PVT1 expression was significantly upregulated by glucose treatment in human mesangial cells, as were levels of FN1, COL4A1, TGFB1, and PAI-1. Importantly, PVT1 knockdown significantly reduced mRNA and protein levels of the major ECM proteins, FN1 and COL4A1, and two key regulators of ECM proteins, TGFB1 and PAI-1. However, we observed a higher and more rapid reduction in levels of secreted FN1, COL4A1, and PAI-1 compared with TGFB1, suggesting that at least some of the PVT1 effects on ECM proteins may be independent of this cytokine. These results indicate that PVT1 may mediate the development and progression of diabetic nephropathy through mechanisms involving ECM accumulation
Cluster of legionnaires’ disease in an Italian prison
Background: Legionella pneumophila (Lp) is the most common etiologic agent causing Legionnaires’ Disease (LD). Water systems offer the best growth conditions for Lp and support its spread by producing aerosols. From 2015 to 2017, the Regional Reference Laboratory of Clinical and Environmental Surveillance of Legionellosis of Palermo monitored the presence of Lp in nine prisons in Western Sicily. During this investigation, we compared Lp isolates from environmental samples in a prison located in Palermo with isolates from two prisoners in the same prison. Methods: We collected 93 water samples from nine Sicilian prisons and the bronchoalveolar lavages (BALs) of two prisoners considered cases of LD. These samples were processed following the procedures described in the Italian Guidelines for the Prevention and Control of Legionellosis of 2015. Then, genotyping was performed on 19 Lp colonies (17 from water samples and 2 from clinical samples) using the Sequence-Based Typing (SBT) method, according to European Study Group for Legionella Infections (ESGLI) protocols. Results: Lp serogroup (sg) 6 was the most prevalent serogroup isolated from the prisons analyzed (40%), followed by Lp sg 1 (16%). Most of all, in four penitentiary institutions, we detected a high concentration of Lp >104 Colony Forming Unit/Liter (CFU/L). The environmental molecular investigation found the following Sequence Types (STs) in Lp sg 6: ST 93, ST 292, ST 461, ST 728, ST 1317 and ST 1362, while most of the isolates in sg 1 belonged to ST 1. We also found a new ST that has since been assigned the number 2451 in the ESGLI-SBT database. From the several Lp sg 1 colonies isolated from the two BALs, we identified ST 2451. Conclusions: In this article, we described the results obtained from environmental and epidemiological investigations of Lp isolated from prisons in Western Sicily. Furthermore, we reported the first cluster of Legionnaires’ in an Italian prison and the molecular typing of Lp sg 1 from one prison’s water system and two BALs, identified the source of the contamination, and discovered a new ST
Evaluating techniques for sampling stream crayfish (paranephrops planifrons)
We evaluated several capture and analysis techniques for estimating abundance and size structure of freshwater crayfish (Paranephrops planifrons) (koura) from a forested North Island, New Zealand stream to provide a methodological basis for future population studies. Direct observation at night and collecting with baited traps were not considered useful. A quadrat sampler was highly biased toward collecting small individuals. Handnetting at night and estimating abundances using the depletion method were not as efficient as handnetting on different dates and analysing by a mark-recapture technique. Electrofishing was effective in collecting koura from different habitats and resulted in the highest abundance estimates, and mark-recapture estimates appeared to be more precise than depletion estimates, especially if multiple recaptures were made. Handnetting captured more large crayfish relative to electrofishing or the quadrat sampler
Detection potential to point-like neutrino sources with the NEMO-km3 telescope
The NEMO Collaboration is conducting an R&D activity towards the construction
of a Mediterranean km3 neutrino telescope. In this work, we present the results
of Monte Carlo simulation studies on the capability of the proposed NEMO
telescope to detect and identify point-like sources of high energy muon
neutrinos.Comment: To be published on BCN06 proceedings (Barcelona, July 4-7, 2006
Signatures of Galaxy-Cluster Interactions: Spiral Galaxy Rotation Curve Asymmetry, Shape, and Extent
The environmental dependencies of the characteristics of spiral galaxy
rotation curves are studied in this work. We use our large, homogeneously
collected sample of 510 cluster spiral galaxy rotation curves to test the claim
that the shape of a galaxy's rotation curve strongly depends on its location
within the cluster, and thus presumably on the strength of the local
intracluster medium and on the frequency and strength of tidal interactions
with the cluster and cluster galaxies. Our data do not corroborate such a
scenario, consistent with the fact that Tully-Fisher residuals are independent
of galaxy location within the cluster; while the average late-type spiral
galaxy shows more rise in the outer parts of its rotation curve than does the
typical early-type spiral galaxy, there is no apparent trend for either subset
with cluster environment. We also investigate as a function of cluster
environment rotation curve asymmetry and the radial distribution of H II region
tracers within galactic disks. Mild trends with projected cluster-centric
distance are observed: (i) the (normalized) radial extent of optical line
emission averaged over all spiral galaxy types shows a 4%+/-2% increase per Mpc
of galaxy-cluster core separation, and (ii) rotation curve asymmetry falls by a
factor of two between the inner and outer cluster for early-type spirals (a
negligible decrease is found for late-type spirals). Such trends are consistent
with spiral disk perturbations or even the stripping of the diffuse, outermost
gaseous regions within the disks as galaxies pass through the dense cluster
cores.Comment: 17 pages; to appear in the April 2001 Astronomical Journa
Adaptive reuse of built heritage in Hong Kong: integrated conservation approach for development
In this paper, references will be drawn from discussions at the one-day international conference organised by RICS on 9 January 2015. Several important case studies in Hong Kong and overseas were shared and discussed at the conference, from which good practices could be distilled for Hong Kong’s unique challenges. References will also be made to good practice where useful.published_or_final_versio
Quantitative assessment of workflow performance through PH reduction
Copyright © 2016 EAI. Workflows are logical abstraction of processes widely adopted in several contexts. Design and operation of workflows are critical stages where issues not manifested by the single block arise from compositions. To deal with such issues, proper techniques and tools should be implemented as support for workflow designers and operators. This paper proposes a solution for the evaluation of the workflow performance starting from the components' ones. Based on the stochastic characterization of the workflow tasks, phase type distributions and stochastic workflow reduction rules, our approach allows to overcome the limits of existing solutions, considering general response time distributions while providing parametric analysis on customer usage profiles and design alternatives. To demonstrate the effectiveness of the proposed solution an example from literature is evaluated
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